DSPP Scholar Training at the University of Michigan School of Dentistry

摘要 头面部出生缺陷，例如唇裂和腭裂，是最常见的先天性疾病之一 人类的畸形。同样，影响头面部(如头部和颈部)的后天疾病 癌症)通过治疗方式(例如，手术和化疗和放射治疗)或事故(例如， 交通、枪支、烟花)通常会对面部造成严重的功能、结构和审美损害， 嘴巴和头盖骨。这些疾病的治疗通常是复杂的，涉及到 诊所和中心的多学科颅面团队为患者提供全面护理。 尽管最近在治疗方案上取得了进展，但对控制的分子机制缺乏了解 颅面发育和再生仍然是发展更复杂的技术的主要障碍 治疗或更有效地预防这些疾病。 这个NIDCR牙科专业和博士项目的目标是帮助确保一个多样化的人才库 训练有素的科学家可以满足国家的生物医学、行为和临床研究需求。我们 相信这一目标是可以通过将有效招聘、高级 科学和临床培训，精湛的导师，卓越的培训环境。我们利用我们的 现有的非常成功的口腔健康科学博士课程和久负盛名的、经过认可的临床 口腔医学院的专业项目，为专家提供先进的科学和技术支持 临床培训。具体地说，这个七年制项目提供博士培训，包括必修课和选修课， 研究轮换、论文研究、职业生涯和领导力发展，以及临床 支持学者的科学和职业规划的专业培训。我们建议支持我们现有的两个 目前正在攻读牙科专业和博士综合培训的学者，直到他们过渡到 在其专业培训的第二年期间的其他资助机制。在这一点上，我们将接纳两名 新学者，他们将根据出色的学术记录、研究成就和 致力于研究密集的学术生涯，重点是颅面部疾病和障碍 如上所述，支持它们。我们将特别努力从不同的领域和领域招募学者 代表不足的背景。 密歇根大学和牙医学院在研究生教育方面有着悠久的传统， 既以学生为中心，又以教师为主导。我们研究生培养的整体观不仅为学者们做好了准备 学术牙科的专业挑战，但也为他们提供了技能和经验 成为批判性的独立思考者和终身学习者。这使他们能够发展成为临床大师。 拥有公认的独立研究事业。我们的目标是培养一个多样化的和独特的合格的 这将加快我们预防和治疗颅面部疾病和紊乱的可能性。

ABSTRACT Craniofacial birth defects, e.g., cleft lip and cleft palate, are among the most common congenital malformations in humans. Similarly, acquired diseases affecting the craniofacial region (e.g., head and neck cancer) through treatment modalities (e.g., surgery and chemo- and radiation therapy) or accidents (e.g., traffic, firearms, fireworks) often cause significant functional, structural, and esthetic damage to the face, mouth, and cranium. The treatment of these conditions often is complex and involves the coordinated work of the multidisciplinary craniofacial teams at clinics and centers providing comprehensive care for patients. Despite recent advances in treatment options, the lack of knowledge in molecular mechanisms controlling craniofacial development and regeneration remains a major obstacle in development of more sophisticated therapies or more effective prevention of these conditions. The goal of this NIDCR Dental Specialty and PhD Program is to help ensure that a diverse pool of well- trained scientists is available to address the nation’s biomedical, behavioral, and clinical research needs. We are confident that this goal is achievable through programs that incorporate effective recruitment, advanced scientific and clinical training, superb mentors, and an outstanding training environment. We leverage our existing and highly successful Oral Health Sciences PhD program and the well-established, accredited clinical specialty programs at the School of Dentistry to provide a pipeline of experts with advanced scientific and clinical training. Specifically, this 7-year program offers PhD training with required and elective courses, research rotations, dissertation research and career and leadership development, coupled with clinical specialty training that supports scholars’ scientific and career plans. We propose to support our existing two scholars, who are currently pursuing the integrated dental specialty and PhD training, until they transition to other funding mechanisms during the second year of their specialty training. At that point, we will admit two new scholars, who will be selected based on strong academic records, research accomplishments, and commitment to a research-intensive academic career with a focus on craniofacial diseases and disorders and support them as outlined above. We will make a special effort to recruit scholars from diverse and underrepresented backgrounds. The University of Michigan and the School of Dentistry have a long tradition in graduate education, which is both “student-centered and faculty led”. Our holistic view in graduate training not only prepares scholars for professional challenges of the academic dentistry, but also furnishes them with skills and experiences to become critical independent thinkers and life-long learners. This allows them to develop as master clinicians with recognized independent research careers. Our goal is to educate a diverse and uniquely qualified workforce that will accelerate our possibilities to prevent and treat craniofacial diseases and disorders.