Developing and Improving Institutional Animal Resources

开发和改善机构动物资源

• 批准号: 7629544
• 负责人: HARRY N SHAIR
• 金额: $ 50万
• 依托单位: NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-07-16 至 2012-09-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7629544
• 关键词: Animals; Arts; Biomedical Research; Caring; Floor; Goals; Government; Guidelines; Housing; Institutes; Institution; Laboratory Animals; Mental disorders; Mus; New York; Operative Surgical Procedures; Personal Satisfaction; Procedures; Quarantine; Rattus; Regulation; Request for Proposals; Research; Research Training; Rodent; Safety; Testing; Translational Research; animal care; animal facility; animal resource; design; improved; meetings

DESCRIPTION (provided by applicant): This proposal requests support for the renovation of the animal care facility of the New York State Psychiatric Institute (NYSPI), a non-federal institution that focuses on translational research and training related to a broad spectrum of mental disorders. The revised goals are 1) improve and increase housing and testing space for rodents by creating a barrier facility within which all housing and testing of mice and rats will take place, and 2) provide better support facilities. The existing main animal care facility occupies two floors of the Kolb Research Building. Species are intermingled. In the new design, all mice and rats will be housed and tested on a single floor. Housing space will be increased by the elimination of two corridors. Eight new testing rooms will be created, most adjacent to the housing rooms. Thus many rodents will not have to be carried through common corridors to and from testing rooms. There will be two new surgery/procedure rooms: one for mice, one for rats. The quarantine capabilities for importation of mice will be greatly expanded. The proposed renovations are the first step in a long term plan to create a state-of-the-art, expanded animal facility on the top three floors of the research building. The design will meet all government guidelines for the care of laboratory animals and safety regulations for staff. The more rational distribution of species with testing and housing spaces adjacent will improve animal well-being; increase efficiency of husbandry procedures; and facilitate biomedical research and training.

描述（由申请人提供）：本提案要求支持纽约州精神病研究所（NYSPI）的动物护理设施的翻新，NYSPI是一家非联邦机构，专注于与广泛的精神障碍相关的转化研究和培训。修订后的目标是：1）通过创建屏障设施来改善和增加啮齿动物的住房和测试空间，所有小鼠和大鼠的住房和测试都将在屏障设施内进行，以及2）提供更好的支持设施。现有的主要动物护理设施占据了Kolb研究大楼的两层。物种是混合的。在新的设计中，所有的小鼠和大鼠将被安置在一个楼层进行测试。取消两条走廊将增加住房空间。将创建8个新的测试室，大多数与住宿室相邻。因此，许多啮齿动物将不必通过公共走廊进出测试室。将有两个新的手术室：一个用于小鼠，一个用于大鼠。大幅度提高进口鼠的检疫能力。拟议中的翻修是长期计划的第一步，该计划旨在在研究大楼的最高三层建立一个最先进的、扩大的动物设施。该设计将符合所有政府关于实验室动物护理的指导方针和工作人员的安全规定。更合理地分布物种，使试验和饲养空间相邻，将改善动物的福祉;提高畜牧程序的效率;并促进生物医学研究和培训。