Cooperative Multicenter Reproductive Medicine Network (U10)
多中心生殖医学合作网络(U10)
基本信息
- 批准号:7489437
- 负责人:
- 金额:$ 30.55万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2007
- 资助国家:美国
- 起止时间:2007-08-24 至 2012-07-31
- 项目状态:已结题
- 来源:
- 关键词:AndrologyAreaAssisted Reproductive TechnologyBasic ScienceBiomedical ResearchClinicalClinical ProtocolsClinical ResearchClinical Trials DesignCollaborationsCommitComplementComplexCouplesDiscipline of obstetricsEpidemiologistFacultyFundingGoalsGrantGynecologyHealthHealth educationHealth systemHousingHumanInfertilityInstitutionJointsLaboratory ResearchLeiomyomaMedicalMedical centerMichiganMissionMulti-Institutional Clinical TrialNational Institute of Child Health and Human DevelopmentNumbersNursing ResearchObstetrics DepartmentsOperative Surgical ProceduresOvarianPalpablePatient CarePatientsPerformancePharmacologic SubstancePopulationPregnancyPrincipal InvestigatorProtocols documentationPublicationsQualifyingRandomizedRandomized Clinical TrialsRandomized Controlled Clinical TrialsRateReproductive EndocrinologyReproductive MedicineResearchResearch PersonnelResourcesScienceSeminal fluidServicesSiteSyndromeUnited States National Institutes of HealthUniversitiesUrologyUterine hemorrhageUterusVaricoceleWomanWomen&aposs HealthWorkbaseclinical research sitecompare effectivenessconceptdesignendometriosisexperiencefootinterestintrauterine inseminationmalemembermenpatient oriented researchprogramsprotocol developmentresearch facilityresponsesymposiumtrial comparing
项目摘要
DESCRIPTION (provided by applicant): There has been a long standing research and clinical collaboration between Urology and Reproductive Endocrinology at the University of Michigan. This proposal describes the qualifications and experience of the Reproductive Endocrinology and Urology faculty as a clinical research team at the jointly supported Center for Reproductive Medicine (CRM). We outline the tremendous experience of the research staff, and detail the patient population available for carrying out clinical protocols to be designed by the NICHD Reproductive Medicine Unit (RMU) Network. The University of Michigan CRM includes 8 clinicians, who are board certified in Obstetrics and Gynecology, Reproductive Endocrinology or Urology. Working within the Center is a well qualified doctoral epidemiologist and biostatistician and 3 research nurses led by our research nurse coordinator with over 10 years experience in protocol development and implementation available for RMU network protocols. This research team has successfully completed an extensive number of randomized and non randomized clinical trials, some of which were supported by NIH grant support as well as multi-center randomized trials supported by pharmaceutical companies. Faculty in the Center for Reproductive Medicine have extensive translational and clinical research experience in areas of interest to the Network including infertility, andrology, abnormal uterine bleeding, endometriosis, leiomyomata uteri, polycystic ovarian syndrome, and assisted reproductive technology. Six faculty members are currently supported or funded by the NIH in patient oriented research. We bring to the RMU network the full support of the NIH supported General Clinical Research Center, the Departments of Obstetrics and Gynecology and Urology at the University of Michigan and the Women's Program at the Ann Arbor VA Medical Center. A concept protocol is included which proposes to investigate the effect of corrective varicocele surgery in men with an abnormal semen analysis. This trial compares the effectiveness of surgical treatment versus observation to achieve a spontaneous pregnancy or with the aid of intrauterine insemination. It is proposed that varicocele surgery will clearly benefit couples with infertility when the male partner has an abnormal semen analysis and a palpable varicocele. In summary, the research team at the Center for Reproductive Medicine is experienced in multi-center clinical trials and is committed to collaborative protocol development and study consistent with the goals of the RMU network.
描述(由申请人提供):密歇根大学泌尿科和生殖内分泌科之间长期开展研究和临床合作。该提案描述了生殖内分泌学和泌尿科教师作为联合支持的生殖医学中心(CRM)的临床研究团队的资格和经验。我们概述了研究人员的丰富经验,并详细介绍了可用于执行NICHD生殖医学单位(RMU)网络设计的临床方案的患者人群。密歇根大学CRM包括8名临床医生,他们在妇产科,生殖内分泌学或泌尿科获得了认证。在中心内工作的是一名合格的流行病学博士和生物统计学家以及3名研究护士,由我们的研究护士协调员领导,他们在RMU网络协议的协议开发和实施方面拥有10多年的经验。该研究团队成功完成了大量的随机和非随机临床试验,其中一些得到了NIH的资助,以及制药公司支持的多中心随机试验。生殖医学中心的教师在该网络感兴趣的领域拥有广泛的转化和临床研究经验,包括不孕症、男科、异常子宫出血、子宫内膜异位症、子宫平滑肌瘤、多囊卵巢综合征和辅助生殖技术。目前有六名教师在以患者为导向的研究中得到NIH的支持或资助。我们为RMU网络带来了NIH支持的综合临床研究中心、密歇根大学妇产科和泌尿科以及安阿伯VA医疗中心妇女项目的全力支持。包括一个概念协议,提出了研究精索静脉曲张矫正手术的男性精液分析异常的影响。本试验比较了手术治疗与观察以实现自然妊娠或辅助宫腔内人工授精的有效性。有人建议,精索静脉曲张手术将明显有利于不育夫妇时,男性伴侣有一个异常的精液分析和明显的精索静脉曲张。总之,生殖医学中心的研究团队在多中心临床试验方面经验丰富,并致力于与RMU网络的目标一致的合作方案开发和研究。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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GREGORY MICHAEL CHRISTMAN其他文献
GREGORY MICHAEL CHRISTMAN的其他文献
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{{ truncateString('GREGORY MICHAEL CHRISTMAN', 18)}}的其他基金
RCT of GnRH-a for ovarian protection during CYC therapy for rheumatic disease
CYC 治疗风湿病期间 GnRH-a 对卵巢保护作用的随机对照试验
- 批准号:
7979892 - 财政年份:2010
- 资助金额:
$ 30.55万 - 项目类别:
RCT of GnRH-a for ovarian protection during CYC therapy for rheumatic disease
CYC 治疗风湿病期间 GnRH-a 对卵巢保护作用的随机对照试验
- 批准号:
8282643 - 财政年份:2010
- 资助金额:
$ 30.55万 - 项目类别:
RCT of GnRH-a for ovarian protection during CYC therapy for rheumatic disease
CYC 治疗风湿病期间 GnRH-a 对卵巢保护作用的随机对照试验
- 批准号:
8142846 - 财政年份:2010
- 资助金额:
$ 30.55万 - 项目类别:
Cooperative Multicenter Reproductive Medicine Network (U10)
多中心生殖医学合作网络(U10)
- 批准号:
7935598 - 财政年份:2009
- 资助金额:
$ 30.55万 - 项目类别:
Cooperative Multicenter Reproductive Medicine Network (U10)
多中心生殖医学合作网络(U10)
- 批准号:
7293133 - 财政年份:2007
- 资助金额:
$ 30.55万 - 项目类别:
Cooperative Multicenter Reproductive Medicine Network (U10)
多中心生殖医学合作网络(U10)
- 批准号:
8472059 - 财政年份:2007
- 资助金额:
$ 30.55万 - 项目类别:
Cooperative Multicenter Reproductive Medicine Network (U10)
多中心生殖医学合作网络(U10)
- 批准号:
7668010 - 财政年份:2007
- 资助金额:
$ 30.55万 - 项目类别:
Cooperative Multicenter Reproductive Medicine Network (U10)
多中心生殖医学合作网络(U10)
- 批准号:
7905117 - 财政年份:2007
- 资助金额:
$ 30.55万 - 项目类别:
Leiomyomata Uteri: Apoptosis and Cell Survival Pathways
子宫平滑肌瘤:细胞凋亡和细胞存活途径
- 批准号:
7271874 - 财政年份:2003
- 资助金额:
$ 30.55万 - 项目类别:
Leiomyomata Uteri: Apoptosis and Cell Survival Pathways
子宫平滑肌瘤:细胞凋亡和细胞存活途径
- 批准号:
6741156 - 财政年份:2003
- 资助金额:
$ 30.55万 - 项目类别:
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