SBIR 246 - Integrating Patient-Reported Outcomes in Hospice and Palliative

SBIR 246 - 整合临终关怀和姑息治疗中患者报告的结果

• 批准号: 7698293
• 金额: $ 15万
• 依托单位: BRIGHTOUTCOME INC.
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-09-30 至 2009-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7698293
• 关键词: SBIR; 246; Integrating; Patient; Reported

Our long-term objective is to develop a computer system facilitating the use of patient-reported outcomes (PRO) information to monitor patient status and assist clinical decision making for cancer patients under palliative and hospice care. This system will integrate PRO and other clinical data with evidence-based treatment guidelines and pathways to care and interface with and foster collaborative decision making between the patient, caregivers, and the medical care team. This project will leverage the Adapteval architecture for PRO management developed in our other SBIR efforts, already implementing CAT/IRT capability, multiple delivery platforms, graphical reports highlighting clinically meaningful PRO score changes, alert/reminder mechanisms, and CCOW-compliant integration. Considering the project goals and our past and current R&D efforts, we define the specific Phase I technical objectives as follows: 1) define a palliative/hospice care model to integrate PRO assessment results with evidence-based pathways to provide clinical decision support for clinicians and education opportunities for patients and caregivers via literature review, focus groups, and interviews; 2) design a system architecture facilitating the sharing the transfer of PRO-related medical data between cancer clinics, hospices, and patients' homes; 3) develop a working prototype following object-oriented and knowledge-based software development methodologies; and 4) evaluate the usability and usefulness of the prototype solution via controlled pilot tests. It is expected that Phase I results will validate the feasibility of the proposed solution from the perspectives of both practicality and technology for the purpose of Phase II execution and ultimate commercialization.

我们的长期目标是开发一个计算机系统，促进使用患者报告的结果（PRO）的信息，以监测患者的状态，并协助姑息治疗和临终关怀癌症患者的临床决策。该系统将PRO和其他临床数据与循证治疗指南和途径相结合，以进行护理，并与患者、护理人员和医疗护理团队进行交互，促进他们之间的协作决策。该项目将利用我们在其他SBIR工作中开发的用于PRO管理的Adapteval架构，该架构已经实现了CAT/IRT功能、多个交付平台、突出显示有临床意义的PRO评分变化的图形报告、警报/提醒机制以及符合CCOW的集成。考虑到项目目标和我们过去和现在的研发工作，我们确定了具体的I期技术目标如下：1）定义姑息/临终关怀模式，将PRO评估结果与循证路径相结合，通过文献综述、焦点小组和访谈为临床医生提供临床决策支持，为患者和护理人员提供教育机会; 2）设计一个系统架构，以促进癌症诊所、临终关怀机构和病人家庭之间的PRO相关医疗数据的共享传输; 3）按照面向对象和基于知识的软件开发方法开发一个工作原型;以及4）通过受控的试点测试来评估原型解决方案的可用性和有用性。预计第一阶段的结果将从实用性和技术两个角度验证拟议解决方案的可行性，以便第二阶段执行和最终商业化。