Data Management and Statistics

a.目标 Core B在多中心临床试验研究中扮演传统数据协调中心的角色。因此，在本发明中， 核心项目B旨在为核心项目A和C以及项目1-4在三个广泛界定的领域提供支持- 数据采集、数据管理和通信以及数据分析。核心的具体目标 B将（a）促进项目1-4的数据和项目特定数据的获取，（B）开发工具， 确保和监测所有收集数据的准确性和保密性的程序，（c）开发工具 和程序，以帮助主要研究者，执行委员会和科学顾问委员会， 对计划项目进行科学监督和管理，（d）促进沟通， 通过最先进的计算机网络在调查人员之间共享数据，以及（e）提供统计数据， 支持研究人员评估项目1-4的假设。

a. Objectives Core B plays the role of the traditional Data Coordinating Center in multi-site clinical trials research. As such, Core B was designed to provide support to Cores A and C and Projects 1-4 in three broadly defined areas - Data Acquisition, Data Management and Communications, and Data Analysis. The specific objectives of Core B are to (a) facilitate acquisition of data and project specific data for Projects 1-4, (b) develop tools and procedures for ensuring and monitoring the accuracy and confidentiality of all collected data, (c) develop tools and procedures to aid the Principal Investigator, the Executive Committee, and the Scientific Advisory Board in providing scientific oversight and administration of the Program Project, (d) facilitate communication and sharing of data among investigators through state of the art computer networking, and (e) provide statistical support to investigators in the evaluation of Project 1-4 hypotheses.