Data Management and Statistics

A.目标 在多点临床试验研究中，Core B扮演着传统数据协调中心的角色。因此， 核心B旨在为核心A和C以及三个广泛定义领域的项目1-4提供支助-- 数据采集、数据管理和通信以及数据分析。CORE的具体目标 B将(A)便利项目1-4的数据和具体项目数据的获取，(B)开发工具和 确保和监测所有收集的数据的准确性和保密性的程序，(C)开发工具 协助首席调查员、执行委员会和科学咨询委员会 对方案项目进行科学监督和管理，(D)促进沟通和 通过最先进的计算机网络在调查人员之间共享数据，以及(E)提供统计 支持研究人员评估项目1-4假设。

a. Objectives Core B plays the role of the traditional Data Coordinating Center in multi-site clinical trials research. As such, Core B was designed to provide support to Cores A and C and Projects 1-4 in three broadly defined areas - Data Acquisition, Data Management and Communications, and Data Analysis. The specific objectives of Core B are to (a) facilitate acquisition of data and project specific data for Projects 1-4, (b) develop tools and procedures for ensuring and monitoring the accuracy and confidentiality of all collected data, (c) develop tools and procedures to aid the Principal Investigator, the Executive Committee, and the Scientific Advisory Board in providing scientific oversight and administration of the Program Project, (d) facilitate communication and sharing of data among investigators through state of the art computer networking, and (e) provide statistical support to investigators in the evaluation of Project 1-4 hypotheses.