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中文摘要
翻译
描述:(申请人?s描述)面对美国癌症的好转 生存率,癌症死亡率在美国印第安人正在增加。文化 这些差异使得解决这一差距具有挑战性。的缺乏 美国印第安人的卫生保健提供者,几乎没有肿瘤学家,化合物, 形势美国印第安人患者,无法有效沟通 提供者,成为孤立的癌症诊断和治疗,很少 招募到临床试验中虽然美国印第安人的需求 因此,肿瘤学家是迫切的,很少有美国印第安人进入医疗保健 职业。虽然大多数大学的招聘和保留情况令人沮丧, 率,北方亚利桑那大学(NAU)有一个杰出的历史, 美国原住民毕业生然而,在NAU, 研究中心为美国印第安学生提供癌症教育, 社区.在这种伙伴关系中,我们将把 亚利桑那州癌症中心(AZCC)提供美洲印第安学生培训计划 和环境研究虽然存在非正式的教师互动,但目前还没有全面的计划来加强NAU的癌症研究, 协调NAU的美国印第安学生招聘和保留, UofA/AZCC。该提案的目标是(1)启动强大的癌症 在NAU研究,以提高教师的职业发展和培养学生在 癌症研究基础;(2)建立稳定,长期的癌症研究, 教育和外联合作;以及(3)改善体制 有效地影响了美国印第安人的癌症差异, 西南研究计划将集中在致癌作用的 与采矿业有关的化学品。美国 印度学生对这些数据非常感兴趣。因此,这种既得利益 大大提高了我们招募和留住这些学生的潜力, 提供未来的美国印第安人癌症研究人员和肿瘤学家。的 该计划是由行政,规划和发展的核心,在每个 机构。研究活动包括基础科学,癌症教育, 社区外展部分。我们提出了6个试点项目,4个全面项目, 并在项目生命周期内招聘2名新教师。
英文摘要
DESCRIPTION: (Applicant?s Description) In the face of improved US cancer survival, cancer mortality in American Indians is increasing. Cultural differences make addressing this disparity challenging. The paucity of American Indian health care providers, almost none oncologists, compounds the situation. American Indian patients, unable to effectively communicate with providers, become isolated from cancer diagnosis and treatment and are rarely recruited into clinical trials. While the need for American Indian oncologists is therefore urgent, few American Indians enter health care professions. While most universities have dismal recruitment and retention rates, Northern Arizona University (NAU) has a distinguished history of graduating Native American students. At NAU, however, there is no cancer research core to provide cancer education to American Indian students and communities. In this partnership, we will link research programs of the Arizona Cancer Center (AZCC) with American Indian student training programs and environmental research at NAU. While informal faculty interaction exists, there is currently no comprehensive plan to enhance cancer research at NAU or to coordinate American Indian student recruitment and retention at NAU and UofA/AZCC. The objectives of this proposal are to (1)initiate robust cancer research at NAU to enhance faculty career development and train students in cancer research fundamentals; (2) create stable, long-term cancer research, education, and outreach collaboration; and (3) improve institutional effectiveness in impacting the disparity in cancer in American Indians of the Southwest. Research programs will focus on the carcinogenic effects of chemicals associated with the mining industry on reservations. American Indian students have a vital interest in the data. Thus this vested interest greatly enhances our potential to recruit and retain these students and to provide future American Indian cancer researchers and oncologists. The program is guided by administrative, planning and developmental cores at each institution. Research activities include basic science, cancer education, and community outreach components. We propose 6 pilot projects, 4 full projects, and recruitment of 2 new faculty over the project lifetime.
期刊论文(6)
专著(0)
科研奖励(0)
会议论文
DOI: 10.1016/j.bbapap.2013.01.010
发表时间: 2013-04
期刊: BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
影响因子: 3.2
作者: [Ma, Wai Kit, Hendrix, Rachel, Stewart, Claire, Campbell, Eric V., Lavarias, Mitchell, Morris, Kolyn, Nichol, Shauna, Gage, Matthew J.]
通讯作者: Gage, Matthew J.
DOI: 10.1016/j.atmosenv.2011.01.051
发表时间: 2011-04
期刊: ATMOSPHERIC ENVIRONMENT
影响因子: 5
作者: [Robinson, Mann S., Zhao, Min, Zack, Lindsay, Brindley, Christine, Portz, Lillian, Quarterman, Matthew, Long, Xiufen, Herckes, Pierre]
通讯作者: Herckes, Pierre
DOI: 10.1016/j.jinorgbio.2010.10.010
发表时间: 2011-02
期刊: JOURNAL OF INORGANIC BIOCHEMISTRY
影响因子: 3.9
作者: [Heintze, Ellie, Aguilera, Camille, Davis, Malia, Fricker, Avery, Li, Qiang, Martinez, Jesse, Gage, Matthew J.]
通讯作者: Gage, Matthew J.
Conformational detection of p53's oligomeric state by FlAsH Fluorescence.
通过 FlaAsH 荧光对 p53 寡聚状态进行构象检测。
DOI: 10.1016/j.bbrc.2009.04.073
发表时间: 2009
期刊: Biochemical and biophysical research communications
影响因子: 3.1
作者: [Webber,TawnyaM, Allen,AndrewC, Ma,WaiKit, Molloy,RhettG, Kettelkamp,CharisseN, Dow,CaitlinA, Gage,MatthewJ]
通讯作者: Gage,MatthewJ
Investigator Development Core
  • 批准号:
    10207308
  • 项目类别:
  • 资助金额:
    $6.15万
  • 财政年份:
    2017
  • 负责人:
    Diane M Stearns
  • 依托单位:
Investigator Development Core
  • 批准号:
    10207300
  • 项目类别:
  • 资助金额:
    $93.98万
  • 财政年份:
    2017
  • 负责人:
    Diane M Stearns
  • 依托单位:
Developmental Core
  • 批准号:
    8323497
  • 项目类别:
  • 资助金额:
    $111.97万
  • 财政年份:
    2011
  • 负责人:
    Diane M Stearns
  • 依托单位:
CELLULAR GENOTOXICITY OF PHOTOACTIVATED URANIUM
  • 批准号:
    8036952
  • 项目类别:
  • 资助金额:
    $44.7万
  • 财政年份:
    2010
  • 负责人:
    Diane M Stearns
  • 依托单位:
海外基金