Comprehensive NAU/AZCC Cancer Research Partnership

描述：(申请人？S描述)面对美国癌症的改善 存活率，美国印第安人的癌症死亡率正在上升。文化性 差异使解决这一差距具有挑战性。稀缺的 美国印第安人医疗保健提供者，几乎没有肿瘤学家，使 情况。美国印第安人患者，无法有效地与 提供者，变得与癌症诊断和治疗隔离，很少 招募到临床试验中。虽然对美国印第安人的需求 因此肿瘤学家迫在眉睫，很少有美国印第安人进入医疗保健行业 职业。虽然大多数大学的招生和留住情况都很糟糕 北亚利桑那大学(NAU)拥有杰出的历史 毕业的美洲原住民学生。然而，在北大西洋公约大学，没有癌症。 研究核心，为美国印第安人学生和 社区。在这一合作伙伴关系中，我们将把 亚利桑那州癌症中心(AZCC)与美国印第安人学生培训计划 以及NAU的环境研究。虽然存在非正式的教员互动，但目前还没有全面的计划来加强北卡罗来纳大学或 协调美国印第安人学生在北卡罗来纳大学的招生和保留工作 UofA/AZCC。这项提议的目标是(1)启动强健的癌症 在北卡罗来纳大学进行研究，以促进教师职业发展和培训学生 癌症研究基础；(2)创建稳定、长期的癌症研究， 教育和外展协作；以及(3)改善体制 影响美国印第安人癌症差异的有效性 西南。研究项目将集中在三聚氰胺的致癌作用上 与保留地的采矿业有关的化学品。美国人 印度学生对这些数据有着至关重要的兴趣。因此，这种既得利益 极大地增强了我们招收和留住这些学生的潜力，并 提供未来的美国印第安人癌症研究人员和肿瘤学家。这个 计划由行政、规划和发展核心指导 机构。研究活动包括基础科学、癌症教育和 社区外展部分。我们提出了6个试点项目，4个全面项目， 并在项目生命周期内招聘2名新教师。

DESCRIPTION: (Applicant?s Description) In the face of improved US cancer survival, cancer mortality in American Indians is increasing. Cultural differences make addressing this disparity challenging. The paucity of American Indian health care providers, almost none oncologists, compounds the situation. American Indian patients, unable to effectively communicate with providers, become isolated from cancer diagnosis and treatment and are rarely recruited into clinical trials. While the need for American Indian oncologists is therefore urgent, few American Indians enter health care professions. While most universities have dismal recruitment and retention rates, Northern Arizona University (NAU) has a distinguished history of graduating Native American students. At NAU, however, there is no cancer research core to provide cancer education to American Indian students and communities. In this partnership, we will link research programs of the Arizona Cancer Center (AZCC) with American Indian student training programs and environmental research at NAU. While informal faculty interaction exists, there is currently no comprehensive plan to enhance cancer research at NAU or to coordinate American Indian student recruitment and retention at NAU and UofA/AZCC. The objectives of this proposal are to (1)initiate robust cancer research at NAU to enhance faculty career development and train students in cancer research fundamentals; (2) create stable, long-term cancer research, education, and outreach collaboration; and (3) improve institutional effectiveness in impacting the disparity in cancer in American Indians of the Southwest. Research programs will focus on the carcinogenic effects of chemicals associated with the mining industry on reservations. American Indian students have a vital interest in the data. Thus this vested interest greatly enhances our potential to recruit and retain these students and to provide future American Indian cancer researchers and oncologists. The program is guided by administrative, planning and developmental cores at each institution. Research activities include basic science, cancer education, and community outreach components. We propose 6 pilot projects, 4 full projects, and recruitment of 2 new faculty over the project lifetime.