ASU Prevention Research Center for Families in Stress

描述（由申请人提供）：本提案旨在资助亚利桑那州立大学的高级干预和服务研究中心。该中心的重点是对由于面临父母离婚、父母死亡和市中心墨西哥裔美国人向高中过渡的高压力情况而有发展精神健康问题风险的儿童采取预防性干预措施。这些压力因素增加了出现严重精神健康问题的风险，如抑郁症、行为问题、药物滥用和社会适应问题。该建议建立在对这些人群进行了9年富有成效的研究的基础上，这些研究已证明对减少精神健康问题、精神障碍诊断、药物使用和提高学业成绩有效。该提案的总体目标是从以大学为基础的预防干预有效性研究过渡到对社区机构实施的项目有效性的评估。引导这种转变的是一种创新模式，它将疗效试验的结果与营销和质量功能部署的概念和方法相结合。由此产生的在社区机构中主动预测和解决高质量实施预防计划的障碍的系统过程，可以作为一种模式，加速将有效的干预措施运送到能够影响公共卫生的环境中。中心由四个核心组成。主要研究核心采用跨学科的方法来准备在社区机构实施的干预措施。从服务营销，质量管理和教育设计的概念和方法被用来重新设计方案，然后在社区机构实施。跨文化适应方面的专家通力合作，采取既具有文化敏感性又具有文化广泛性的干预措施。多学科小组与家庭法院的主要利益攸关方、与丧亲儿童打交道的机构以及经验丰富的有效性研究人员合作。研究方法核心开发了方法论学家和实质性研究人员的合作工作组，重点关注五个方法论问题；测量、结果的可变性、干预措施的实施和依从性、多层次数据和经济分析。研究网络发展核心与家庭法院、提供者机构和丧亲机构开展合作，在社区环境中实施基于证据的预防方案。运营核心为中心决策和管理、基于网络的数据收集、数据管理、统计分析、道德问题分析和培训提供关键基础设施。

DESCRIPTION (provided by applicant): This proposal is to fund an Advanced Center for Intervention and Services Research at Arizona State University. The Center focuses on preventive interventions for children who are at risk for developing mental health problems because of exposure to the high stress situations of parental divorce, parental death and inner-city, Mexican American children in transition to high school. These stressors increase risk for development of serious mental health problems such as depression, conduct problems, substance abuse and social adaptation problems. The proposal builds on a 9-year history of productive research with these populations, which has demonstrated efficacy to reduce mental health problems, diagnosis of mental disorder, substance use and to improve academic achievement. The overall objective of the proposal is transition from University-based studies of the efficacy of preventive interventions to the evaluation of effectiveness of programs implemented in community agencies. Guiding this transition is an innovative model that integrates findings from efficacy trials with marketing and quality function deployment concepts and methods. The resulting systematic process of proactively anticipating and resolving barriers to high quality implementation of prevention programs in community agencies can serve as a model to speed the transportation of efficacious interventions into settings where they can affect public health. The Center consists of four Cores. The Principal Research Core utilizes an interdisciplinary approach to prepare the interventions for delivery in community agencies. Concepts and methods from service marketing, and quality management and educational design are used to redesign the programs fore implementation in community agencies. Experts on cross-cultural adaptation collaborate to make interventions that are culturally sensitive yet culturally broad. The multidisciplinary teams work with key stakeholders in Family Courts and agencies that work with bereaved children and experienced effectiveness researchers. The Research Methods Core develops collaborative workgroups of methodologists and substantive researchers to focus on five methodological issues; measurement, variability in outcomes, implementation and compliance with interventions, multilevel data, and economic analysis. The Research Network Development Core develops collaborations with Family Courts, provider agencies and Bereavement Agencies to implement evidence based prevention programs in community settings. The Operations Core provides critical infrastructure for Center decision making and management, web-based data collection, data management, statistical analysis, analysis of ethical issues and training. OPERATIONS CORE