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Physical Activity, Disability, and Health Utility in Rheumatic Disease

风湿病中的体力活动、残疾和健康效用

基本信息

批准号：
7665022
负责人：
DOROTHY D. DUNLOP
金额：
$ 22.15万
依托单位：
NORTHWESTERN UNIVERSITY AT CHICAGO
依托单位国家：
美国
项目类别：
财政年份：
2008
资助国家：
美国
起止时间：
2008-08-01 至 2012-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7665022
关键词：
Activities of Daily Living Address Adult Affective American American College of Radiology Ancillary Study Arthritis Arts Attenuated Cardiovascular system Caring Clinical Clinical Trials Design Cognition Disorders Communities Control Groups Cost Effectiveness Analysis Counseling Daily Data Degenerative polyarthritis Demographic Aging Dependency Disabled Persons Disease Disease Management Economics Education Effectiveness Employment Enrollment Equilibrium Evaluation Exercise Faculty Foundations Funding Gender General Population Generic Drugs Goals Guidelines Health Health Care Costs Health Policy Health Status Healthcare Independent Living Individual Institutes Intervention Interview Investigation Joints Knee Osteoarthritis Light Link Maps Measures Mediating Medical Medicine Mission Observational Study Occupational Therapy Outcome Pain Patients Performance Persons Physical Function Physical Medicine Physical activity Physical environment Physical therapy Physicians Policies Policy Analysis Population Premature Mortality Preventive Medicine Process Productivity Public Health Public Policy Publications Purpose Quality of life Quality-Adjusted Life Years Questionnaires Race Randomized Randomized Clinical Trials Rate Reading Reporting Research Research Personnel Retirement Rheumatism Rheumatoid Arthritis Rheumatology Risk SF-36 Score Self Care Severity of illness Societies Speed Standards of Weights and Measures Surgeon Telephone Interviews Testing Translating Universities Upper arm Variant Walking Week Work base behavior change cohort college community living cost cost effectiveness day demographics disability fitness health related quality of life illness length improved indexing instrument instrumental activity of daily living interest light intensity multidisciplinary preference programs protective effect social symposium treatment planning

项目摘要

Arthritis is a costly disease to society and the individual. The annual costs in the US due to arthritis exceed $86 billion. Nearly 8 million Americans are disabled as a result of their arthritis, making arthritis a primary cause of disability in the US. Knee osteoarthritis (OA) and rheumatoid arthritis (RA) are major causes of arthritis-related disability. Physical activity is a promising weapon in the public health arsenal to improve the health of persons with arthritis. Our recent work indicates that increased levels of physical activity reduced disability progression in an observational cohort of adults with arthritis. Since medical costs due to arthritis are strongly driven by disability, identifying an implementable physical activity intervention that reduces disability among persons with arthritis may provide an effective strategy to contain rising health care costs due to arthritis To examine disability progression and economic issues relevant to the promotion of physical activity in rheumatic disease, an ancillary study to the Physical Activity Management (PAM) Trial is proposed. The PAM Trial is an NIH-funded randomized clinical trial enrolling 480 patients with knee OA and RA. The funded mission of the PAM Trial is to test the effectiveness in terms of health status of a physical activity management program to augment physician physical activity promotion (PAM group) compared to only physician promotion of physical activity (control group). This ancillary study extends this randomized clinical trial beyond clinical outcomes to factors relevant to pubic policy evaluations of this intervention. The proposed ancillary study requests funds to add 1) disability measures, 2) a community-based health utility assessment of health related quality of life, and 3) medical utilization measures to the funded PAM Trial. These new measures will extend the evaluation of PAM physical activity management beyond its effect on pain and health status to an assessment of policy-relevant outcomes. Specifically, this randomized clinical trial will be used to determine if PAM is a cost-effective intervention that reduces disability progression and improves health related quality of life of patients with arthritis. This is key information for policy evaluations related to the potential large scale dissemination of the PAM intervention into widespread practice. Findings from this study will advance public health and policy efforts to reduce disability, rising health care costs, and improve the quality of life among 48 million US adults having arthritis.

关节炎对社会和个人来说都是一种代价高昂的疾病。美国每年因关节炎的花费