课题基金 / 基金详情

REPLICATING VIRAL VECTOR AS NEONATAL VACCINE TO PREVENT ORAL SIV TRANSMISSION

REPLICATING VIRAL VECTOR AS NEONATAL VACCINE TO PREVENT ORAL SIV TRANSMISSION
复制病毒载体作为新生儿疫苗以预防 SIV 口腔传播
批准号：
7715604
负责人：
Marta L Marthas
金额：
$16.9万
依托单位：
UNIVERSITY OF CALIFORNIA AT DAVIS
依托单位国家：
美国
项目类别：
财政年份：
2008
资助国家：
美国
项目状态：
已结题
起止时间：
2008-05-01 至 2009-04-30
来源：
https://reporter.nih.gov/project-details/7715604
关键词：
AttenuatedComputer Retrieval of Information on Scientific Projects DatabaseExposure toFundingGastrointestinal tract structureGrantHIVHIV vaccineHuman MilkImmunityInfantInstitutionNeonatalOralOral cavityProteinsResearchResearch PersonnelResourcesSiteSourceUnited States National Institutes of HealthVaccinesViral VectorViruspreventtransmission process

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中文摘要
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英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Objective: To provide protection against repeated exposure to HIV in breast milk, a neonatal HIV vaccine should elicit anti-HIV immunity at the initial site of virus exposure the oral cavity as well as throughout the infant's body. Attenuated viruses that stably express HIV proteins and replicate in the oral cavity and the gastrointestinal tract could be efficient HIV vaccines.
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REPLICATING VIRAL VECTOR AS NEONATAL VACCINE TO PREVENT ORAL SIV TRANSMISSION
REPLICATING VIRAL VECTOR AS NEONATAL VACCINE TO PREVENT ORAL SIV TRANSMISSION
VACCINE-ELICITED ANTIBODY DEPENDENT CELL CYTOTOXICITY IN PROTECTION AGAINST SIV
REPLICATING VIRAL VECTOR AS NEONATAL VACCINE TO PREVENT ORAL SIV TRANSMISSION