CLINICAL TRIAL: ALENDRONATE SODIUM IN JUVENILE OSTEOPOROSIS

临床试验：阿仑膦酸钠治疗青少年骨质疏松症

• 批准号: 7719577
• 负责人: L. LYNDON KEY
• 金额: $ 0.89万
• 依托单位: MEDICAL UNIVERSITY OF SOUTH CAROLINA
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-05-01 至 2009-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7719577
• 关键词: Adolescent; Bone Diseases; Child; Clinical Trials; Computer Retrieval of Information on Scientific Projects Database; Deformity; Female; Fosamax; Fracture; Funding; Grant; Institution; Investigational Drugs; Osteoporosis; Patients; Pharmaceutical Preparations; Puberty; Research; Research Personnel; Resources; Safety; Skeletal system; Source; Trihydrate Alendronate Monosodium Salt; United States Food and Drug Administration; United States National Institutes of Health; bone; design; male; prevent; treatment duration

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Juvenile Osteoporosis (soft or weak bones that can fracture) occurs in both male and female children and adolescents. It is an uncommon bone disease that occurs just before puberty and the cause is unknown. The rationale for the treatment is to prevent the occurrence of fractures and skeletal deformities. Twenty children with osteoporosis will participate in the study. The drug Fosamax was shown to be effective for the treatment of osteoporosis in children in our earlier study. This study is designed to determine further the safety and efficacy of Fosamax therapy. Fosamax is considered an investigational drug by the FDA for its use during this study. The duration of the project is 3 years and the duration of the patient treatment is 2 years involving 24 months treatment period and 24 months untreated period.

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