SNP PROFILE OF RADIOSENSITIVE-RELEVANT GENES/ADVERSE REACTION IN PROSTATE CANCER

前列腺癌中放射敏感相关基因/不良反应的 SNP 谱

• 批准号: 7719630
• 负责人: YUAN ZHU
• 金额: $ 0.08万
• 依托单位: MEDICAL UNIVERSITY OF SOUTH CAROLINA
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-05-01 至 2009-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7719630
• 关键词: Adverse event; Adverse reactions; African American; Computer Retrieval of Information on Scientific Projects Database; Dose; Funding; Genes; Genetic Polymorphism; Genetic Variation; Goals; Grant; Institution; Malignant neoplasm of prostate; Predisposition; Radiation; Radiation therapy; Research; Research Personnel; Resources; Source; United States National Institutes of Health; men

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The goal of this study is investigate the association between genetic variations that influence susceptibility to adverse events associated with radiation therapy in African-American men with prostate cancer. The PI hypothesizes that if they identify polymorphism in genes that correlate with adverse events associated with radiotherapy, it is possible to alter the radiation dose given to the subject to reduce or eliminate these adverse events.

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 这项研究的目的是调查在患有前列腺癌的非裔美国男性中，影响放射治疗相关不良事件易感性的基因变异之间的联系。PI假设，如果他们发现与放射治疗相关的不良事件相关的基因多态性，就有可能改变给予受试者的辐射剂量，以减少或消除这些不良事件。