CLINICAL TRIAL: CLINICAL BEHAVIOR OF LITHIUM DISILICATE, SINGLE-UNIT, CAD/CAM CR

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 这项试验将检查40个单位冠(25个后冠和15个前冠)在至少2年的时间内的表现。牙冠将使用计算机辅助设计/计算机辅助加工(CAD/CAM)工艺由二硅酸锂微晶玻璃制成。材料和加工设备均通过FDA 510-K认证，可用于临床应用。首席研究员(PI)在康涅狄格州大学发起了这项试验，作为对正在进行的实验室工作的重要补充，以更好地了解临床行为，并帮助正在进行的研究，开发经过验证的陶瓷-陶瓷兼容性和整体断裂的实验室测试。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This trial will examine the performance of 40 single unit crowns (25 posterior and 15 anterior) for a period of at least 2 years. Crowns will be fabricated from a lithium disilicate glass-ceramic using a computer-aided design/computer-aided machining (CAD/CAM) process. Both the material and the processing equipment have FDA 510-K clearance for this clinical application. The principal investigator (PI) initiated this trial at UConn as an important complement to ongoing laboratory efforts to better understand clinical behavior and aid ongoing research into the development of validated laboratory tests of ceramic-ceramic compatibility and bulk fracture.