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EFFECT OF HYDROXYUREA ON BLOOD COAGULATION IN PATIENT WITH SICKLE CELL DISEASE

EFFECT OF HYDROXYUREA ON BLOOD COAGULATION IN PATIENT WITH SICKLE CELL DISEASE
羟基脲对镰状细胞病患者凝血的影响
批准号：
7716787
负责人：
Kenneth I Ataga
金额：
$0.05万
依托单位：
UNIV OF NORTH CAROLINA CHAPEL HILL
依托单位国家：
美国
项目类别：
财政年份：
2008
资助国家：
美国
项目状态：
已结题
起止时间：
2008-04-02 至 2008-05-31
来源：
https://reporter.nih.gov/project-details/7716787
关键词：
AffectBlood coagulationCoagulation ProcessComputer Retrieval of Information on Scientific Projects DatabaseFundingGrantInstitutionPatientsPurposeResearchResearch PersonnelResourcesSickle Cell AnemiaSourceSystemUnited States National Institutes of Healthhydroxyurearesearch study

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中文摘要
翻译
这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 这项研究的目的是找出：1)羟基尿素治疗如何影响镰状细胞病患者在稳定、非危象期的凝血系统；以及2)在镰状细胞病患者中，凝血系统的激活与血管闭塞并发症(血管阻塞并发症)之间有什么关系。
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this research study is to find out: 1) how hydroxyurea therapy affects the coagulation system in sickle cell disease patients during stable, non-crisis periods; and 2) what the relationship is between activation of the coagulation system and vaso-occlusive complications (complications from blockage of vessels) in patients with sickle cell disease.
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会议论文
Predicting Progression of Chronic Kidney Disease in Sickle Cell Anemia Using Machine Learning Models (PREMIER)
Predicting Progression of Chronic Kidney Disease in Sickle Cell Anemia Using Machine Learning Models (PREMIER)
THE ASSOCIATION OF BIOMARKERS OF ENDOTHELIAL FUNCTION WITH PROSPECTIVE CHANGES IN KIDNEY FUNCTION IN SICKLE CELL ANEMIA
THE ASSOCIATION OF BIOMARKERS OF ENDOTHELIAL FUNCTION WITH PROSPECTIVE CHANGES IN KIDNEY FUNCTION IN SICKLE CELL ANEMIA
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