EVAL OF PLANT STEROL ESTER & PLACEBO ON LOW-DENSITY LIPOPROTEIN CONCENTRATIONS

植物甾醇酯的评价

• 批准号: 7719474
• 负责人: SUNNY LINNEBUR
• 金额: $ 0.4万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-04-01 至 2008-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7719474
• 关键词: Cessation of life; Cholesterol; Colesevelam hydrochloride; Computer Retrieval of Information on Scientific Projects Database; Drug Interactions; Funding; Goals; Grant; Heart; Heart Diseases; Institution; Juice; Low-Density Lipoproteins; Marketing; Myocardial Infarction; Oranges; Pharmaceutical Preparations; Phytosterols; Placebos; Research; Research Personnel; Resources; Source; United States National Institutes of Health; Woman; men; sterol ester

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Lowering cholesterol has been shown to reduce heart attacks and deaths related to heart disease. There are many medications available in the U.S. to lower cholesterol. Some medications are absorbed into the body and cause drug interactions with other medications. However, some medications lower cholesterol without being absorbed into the body. Recently, orange juice that lowers cholesterol has been marketed in the U.S. by the Minute Maid Corporation. The goal of this study is to better understand the effects of the cholesterol-lowering drug Welchol¿, which is not absorbed into the body, in combination with cholesterol-lowering orange juice (Minute Maid Heart Wise¿) in men and women with high cholesterol.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 降低胆固醇已被证明可以减少心脏病发作和与心脏病相关的死亡。 在美国有许多药物可以降低胆固醇。 有些药物被吸收到体内并导致与其他药物的药物相互作用。 然而，有些药物可以降低胆固醇，但不会被体内吸收。 最近，美汁源公司在美国销售了降低胆固醇的橙汁。 这项研究的目的是更好地了解降胆固醇药物 Welchol（不被人体吸收）与降胆固醇橙汁（美汁源 Heart Wise）联合使用对高胆固醇男性和女性的影响。