Molecular mechanisms controlling mitochondrial dynamics

控制线粒体动力学的分子机制

• 批准号: nhmrc : 1049968
• 负责人: Dr Diana Stojanovski
• 金额: $ 36.59万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/molecular-mechanisms-controlling-mitochondrial-dynamics/112129
• 关键词: Molecular; mechanisms; controlling; mitochondrial; dynamics

Mitochondria are both the powerhouses and the poison cupboard of our cells. They have evolved from bacteria and still possess the ability to grow and divide. Unregulated mitochondrial division is seen in dying cells and in cells from patients with neurodegenerative diseases. We have identified new molecules involved in mitochondrial division and are investigating how they function in normal and unhealthy cells.

线粒体既是我们细胞的发电站，也是我们细胞的毒柜。它们是从细菌进化而来的，仍然具有生长和分裂的能力。在垂死细胞和神经退行性疾病患者的细胞中观察到不受调节的线粒体分裂。我们已经确定了参与线粒体分裂的新分子，并正在研究它们在正常和不健康细胞中的功能。