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B-CLL SUBGROUPS: MATURATION STAGE & GENE EXPRESSION

B-CLL SUBGROUPS: MATURATION STAGE & GENE EXPRESSION
B-CLL 亚群：成熟阶段
批准号：
7719248
负责人：
Nicholas Chiorazzi
金额：
$15.29万
依托单位：
FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH
依托单位国家：
美国
项目类别：
财政年份：
2008
资助国家：
美国
项目状态：
已结题
起止时间：
2008-04-22 至 2009-03-31
来源：
https://reporter.nih.gov/project-details/7719248
关键词：
CategoriesChronic Lymphocytic LeukemiaClinicalComputer Retrieval of Information on Scientific Projects DatabaseDiseaseFundingGene ExpressionGene MutationGrantInstitutionPatientsResearchResearch PersonnelResourcesSourceStagingSubgroupUnited States National Institutes of Healthbasedesign

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中文摘要
翻译
该子项目是利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得主要资金， 因此可以在其他CRISP条目中表示。列出的机构是 中心，不一定是研究者的机构。 近年来研究发现，B型慢性淋巴细胞白血病（B-CLL）可根据IgV基因突变和CD 38表达分为两个亚群。两组患者的临床病程不同。 该提案旨在更准确地了解这两大类B-CLL案件的区别。
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Recent studies have found that the disease B-type chronic lymphocytic leukemia (B-CLL) can be divided into two subgroups based on lg V gene mutation status and CD 38 expression. The patients in these two groups follow different clinical courses. This proposal is designed to understand more precisely how these two broad categories of B-CLL cases differ.
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