B-CLL SUBGROUPS: MATURATION STAGE & GENE EXPRESSION

B-CLL 亚群：成熟阶段

• 批准号: 8167214
• 负责人: Nicholas Chiorazzi
• 金额: $ 0.04万
• 依托单位: FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-04-01 至 2011-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8167214
• 关键词: Categories; Chronic Lymphocytic Leukemia; Clinical; Computer Retrieval of Information on Scientific Projects Database; Disease; Funding; Gene Expression; Gene Mutation; Grant; Institution; Patients; Research; Research Personnel; Resources; Source; Staging; Subgroup; United States National Institutes of Health; base; design

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Recent studies have found that the disease B-type chronic lymphocytic leukemia (B-CLL) can be divided into two subgroups based on lg V gene mutation status and CD 38 expression. The patients in these two groups follow different clinical courses. This proposal is designed to understand more precisely how these two broad categories of B-CLL cases differ.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 近年来研究发现，B型慢性淋巴细胞白血病（B-CLL）可根据IgV基因突变和CD 38表达分为两个亚群。两组患者的临床病程不同。 该提案旨在更准确地了解这两大类B-CLL病例的不同之处。