AEROBIC PERFORMANCE, MOBILITY LIMITATIONS & EXERCISE IN OLDER ADULTS W/ DIABETES

有氧运动表现、活动能力限制

• 批准号: 7603794
• 负责人: Caroline S Blaum
• 金额: $ 2.42万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-03-01 至 2007-09-16
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7603794
• 关键词: Aerobic; African American; Asian Americans; Behavior Therapy; Behavioral; Blood Tests; Code; Computer Retrieval of Information on Scientific Projects Database; Confidentiality; Consent; County; DEXA; Data; Diabetes Mellitus; Echocardiography; Elderly; Exercise; Funding; Goals; Grant; Health Insurance Portability and Accountability Act; Health education; Hispanics; Home environment; Hospitalization; Institution; Intervention; Interview; Kinetics; Location; Measures; Medical Records; Names; Numbers; Other Minority; Oxygen; Patient Self-Report; Performance; Physical activity; Physicians; Pliability; Population; Process; Protocols documentation; Purpose; Questionnaires; Randomized Controlled Trials; Recruitment Activity; Research; Research Personnel; Resources; Scanning; Source; Testing; Training Activity; United States National Institutes of Health; Visit; Writing; base; diabetic; human subject; improved; programs; response; sex

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is to conduct a randomized controlled trial in 240 older adults with diabetes to determine the effects of functional circuit training and activity tailored intervention/behavioral support (with a home program of behavioral support) or flexibility controls and a program of health education and no behavioral support) on measures of peak aerobic capacity, submaximal oxygen kinetics, functional mobility performance and self-reported function. Both sexes will be recruited. We will particularly encourage African Americans in our recruitment, with a goal of attaining a distribution similar to that of older diabetics. Other minorities will be recruited based on their percentage in Washtenaw county and western Wayne county, the primary recruitment region (3% Asian American, and 2% Hispanic). No vulnerable (such as demented) populations will be involved. We propose to test the hypothesis that aerobic performance is associated with mobility limitations, and that an intervention to improve aerobic performance will also improve mobility. Given the low physical activity levels of many older adults with diabetes we will specifically test whether exercise interventions that improve submaximal aerobic performance also improve mobility. The majority of data collected will be directly from the human subject, in the form of questionnaire responses, actual observed performance, blood tests, DEXA scan and echocardiogram. We will also request to corroborate the subject interview with inspection of their medical records which can include information about their number of physician visits and hospitalizations related to diabetes. All HIPAA requirements will be carefully followed. Confidentiality will be maintained to the fullest extent possible. Longstanding protocols have been in place, including data coding by subject number, locked in file cabinets, and cross-referenced by a name-number key in another location. A comprehensive written consent process will be employed.'

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 本研究的目的是在240名老年糖尿病患者中进行随机对照试验，以确定功能电路训练和活动定制干预/行为支持的效果（有行为支持的家庭计划）或灵活性控制和健康教育计划，没有行为支持）对峰值有氧能力，次最大氧动力学，功能移动性能和自我报告功能。男女都将被招募。我们将特别鼓励非裔美国人参与我们的招募，目标是实现与老年糖尿病患者相似的分布。其他少数族裔将根据他们在华盛顿县和西部韦恩县的比例招募，这是主要招募地区（3%亚裔美国人和2%西班牙裔）。不涉及弱势群体（如痴呆症）。我们建议测试的假设，有氧性能与流动性限制，并干预，以提高有氧性能也将提高流动性。鉴于许多老年糖尿病患者的体力活动水平较低，我们将专门测试改善次最大有氧运动能力的运动干预是否也能改善活动能力。收集的大部分数据将直接来自人类受试者，形式为问卷回答、实际观察到的性能、血液检查、DEXA扫描和超声心动图。我们还将要求通过检查受试者的医疗记录来证实受试者的访谈，其中可能包括与糖尿病相关的医生就诊和住院次数的信息。我们将严格遵守所有的HIPAA要求。将尽可能保持机密。长期以来的协议已经到位，包括按受试者编号进行数据编码，锁在文件柜中，并通过另一个位置的名称-编号键进行交叉引用。将采用全面的书面同意程序。'