GUIDED IMAGERY STRESS REDUCTION INTERVENTION FOR OBESE LATINO ADOLESCENTS: TH

该子项目是利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得主要资金， 因此可以在其他CRISP条目中表示。列出的机构是 中心，不一定是研究者的机构。 这项试点和可行性研究的总体目标是：1）开发一种为期12周的、基于理论的、引导性意象生活方式干预，以减少超重拉丁裔青少年中2型糖尿病和心血管疾病的风险因素; 2）测试意象干预的前4周对研究人群中压力、压力激素（皮质醇）水平和糖尿病风险因素的影响。焦点小组定性方法将用于开发引导性图像干预，之后12名受试者将被随机分配到非干预对照组和研究组，研究组将接受每周4次的减压引导性图像课程。将在研究组和对照组之间比较干预前和干预后的压力、唾液和尿液游离皮质醇、葡萄糖耐量、胰岛素敏感性和分泌指数、身体成分和血脂评估。如果引导图像被证明是有效的，在减少压力，压力激素水平和糖尿病的危险因素，这将是一个重要的，创新的，行为干预的方法，肥胖和2型糖尿病超重的拉丁美洲青少年日益严重的问题。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The overall aim of this pilot and feasibility study is to 1)develop a 12-week, theory-based, guided imagery lifestyle intervention to reduce risk factors for type 2 diabetes and cardiovascular disease in overweight Latino adolescents; and 2) to test the effects of the first 4 weeeks of the imagery intervention on stress, stress hormone (cortisol) levels, and diabetes risk factors in the study population. Focus group qualitative methodologies will be used to develop the guided imagery intervention, after which 12 subjects will be randomized into a non-intervention control group, and a study group that will receive 4 weekly stress-reduction guided imagery sessions. Pre- and post-intervention assessments of stress, salivary and urinary free cortisol, glucose tolerance, indices of insulin sensitivity and secretion, body composition, and plasma lipids will be compared between study and control groups. If guided imagery is shown to be effective at reducing stress, stress hormone levels, and diabetes risk factors, this would represent a significant, and innovative, behavioral intervention approach to the increasing problem of obesity and type 2 diabetes in overweight Latino adolescents.