VisualSonics Vevo 2100

威视 Vevo 2100

• 批准号: 7794593
• 负责人: Burns C Blaxall
• 金额: $ 44.55万
• 依托单位: UNIVERSITY OF ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-01 至 2010-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7794593
• 关键词: Academic Medical Centers; Animal Experimentation; Animals; Arts; Cardiovascular system; Clinical and Translational Science Awards; Color; Commit; Discipline; Doctor of Philosophy; Faculty; Fostering; Functional disorder; Funding; Growth; Housing; Image; Individual; Lymphatic; Malignant Neoplasms; Medical center; Methods; Modality; Musculoskeletal Diseases; Nature; Operative Surgical Procedures; Perfusion; Physiologic pulse; Program Research Project Grants; Research; Research Design; Research Institute; Research Personnel; Resolution; Running; System; Time; Tissues; Training; Training Support; Transducers; Translational Research; Ultrasonography; Universities; base; cardiovascular imaging; cost; experience; fetal; hospice environment; imaging modality; instrument; instrumentation; interest; malformation; programs; public health relevance; reconstruction; skills

DESCRIPTION (provided by applicant): We are requesting funds to purchase a VisualSonics Vevo 2100 ultrasound imaging system for incorporation into the small animal Ultrasound Imaging Core at the University of Rochester Medical Center (URMC), an original awardee of the Clinical and Translational Science Award. VisualSonics is the only company in the world that manufactures high-resolution ultrasound imaging modalities targeted specifically to research animals. The newly introduced Vevo 2100 is a revolutionary, state of the art high-resolution ultrasound imaging system specifically designed for research animals. The Vevo 2100 has several enhancements over the earlier Vevo 770, including linear array transducers (probes), strain imaging, tissue doppler imaging, pulse wave Doppler, color Doppler, power Doppler, 3D reconstruction, contrast imaging, and contrast perfusion imaging. These new modalities provide unparalleled, revolutionary advancements regarding all aspects of non-invasive longitudinal cardiovascular imaging in particular, and small animal imaging in general. The Aab Cardiovascular Research Institute (Aab CVRI) at the University of Rochester Medical Center (URMC) currently has over three years experience operating a Vevo 770 in cardiovascular projects, including our Program Project Grant (B Berk, PI). This instrument is heavily used by investigators both within the Aab CVRI and throughout the URMC, and is near capacity. Due to the increased demand for non-invasive imaging of small animals, the current instrumentation within the URMC is no longer adequate. The Vevo 2100 provides unique imaging capabilities that are unavailable with the Vevo 770. To broaden access to the transformative nature of small animal ultrasound imaging, the current Vevo 770 will be upgraded using already committed institutional funds, and will be moved to the main URMC campus where it will broaden the availability of ultrasound imaging to a cadre of well funded investigators with well-established interest and expertise in ultrasound imaging. The availability of both machines will serve to expand the availability of high-resolution ultrasound imaging while at the same time expanding our imaging capabilities. The Vevo 2100 will housed in the Aab CVRI Surgery/Imaging Core under the hospice of the institutional Ultrasound Core. Within the Aab CVRI, the Vevo system is utilized, run and managed by a group of 18 well-funded PhD and MD investigators with extensive ultrasound imaging experience. In addition, well-trained support staff are in place to run the machine and to train new users of both the Vevo 2100 and Vevo 770. In summary, the transformative nature of the Vevo 2100 and expanded availability of small animal ultrasound imaging would not only maintain both the Aab CVRI and URMC at the cutting edge of translational research, but would further enhance our ability to attract the best and brightest cardiovascular investigators, produce sought-after trainees with cutting edge training and marketable skills, and foster continued, long-term growth of both the Aab CVRI and URMC funding and faculty, creating opportunities for numerous individual R01s and Program Project Grants across multiple disciplines. PUBLIC HEALTH RELEVANCE: Advanced small animal ultrasound imaging permits non-invasive tissue imaging, enabling enormous refinement in investigational methods that can also reduce the numbers of animals used. The Aab Cardiovascular Research Institute has an established ultrasound-based research program that will take full advantage of the VisualSonics Vevo 2100, a new state-of-the-art instrument. In a cost-effective expansion of ultrasound imaging to the entire University of Rochester Medical Center, the existing instrument will be upgraded and relocated to the main medical center campus, thus transforming both cardiovascular research and existing research programs in cancer, musculoskeletal disease, lymphatic dysfunction, and fetal malformation.

描述（由申请人提供）：我们要求资金购买Visualsics VEVO 2100超声成像系统，以融入罗切斯特医学中心（University of Rochester Medical Center）（URMC）的小型动物超声成像核心（URMC），这是临床和翻译科学奖的原始获奖者。 Visualsonics是世界上唯一制造专门针对研究动物的高分辨率超声成像方式的公司。新引入的VEVO 2100是一种革命性的，最先进的高分辨率超声成像系统，专门为研究动物设计。 VEVO 2100比较早的VEVO 770具有多种增强功能，包括线性阵列传感器（探针），应变成像，组织多普勒成像，脉搏波多普勒，颜色多普勒，功率多普勒，功率多普勒，3D重建，对比成像，对比成像和对比造成的灌注成像。这些新的方式尤其是非侵入性纵向心血管成像的所有方面以及一般的小动物成像，提供了无与伦比的革命性进步。罗切斯特大学医学中心（URMC）的AAB心血管研究所（AAB CVRI）目前拥有三年多的经验，经营着在心血管项目中的VEVO 770，包括我们的计划项目Grant（Berk，PI）。该仪器在AAB CVRI和整个URMC中都被研究人员大量使用，并且接近容量。由于对小动物的非侵入性成像的需求增加，URMC内的当前仪器不再足够。 The Vevo 2100 provides unique imaging capabilities that are unavailable with the Vevo 770. To broaden access to the transformative nature of small animal ultrasound imaging, the current Vevo 770 will be upgraded using already committed institutional funds, and will be moved to the main URMC campus where it will broaden the availability of ultrasound imaging to a cadre of well funded investigators with well-established interest and expertise in超声成像。两种机器的可用性都将有助于扩大高分辨率超声成像的可用性，同时扩大我们的成像功能。 VEVO 2100将安置在机构超声核心临终关怀的AAB CVRI手术/成像核心中。在AAB CVRI中，VEVO系统由一组拥有丰富超声成像经验的18个资金资助的博士和MD研究人员组成，运行和管理。 In addition, well-trained support staff are in place to run the machine and to train new users of both the Vevo 2100 and Vevo 770. In summary, the transformative nature of the Vevo 2100 and expanded availability of small animal ultrasound imaging would not only maintain both the Aab CVRI and URMC at the cutting edge of translational research, but would further enhance our ability to attract the best and brightest cardiovascular investigators, produce sought-after具有尖端培训和可销售技能的受训人员，以及福斯特（Foster）的持续，AAB CVRI和URMC资金和教职员工的长期增长，为跨多个学科的众多个人R01和计划项目提供了机会。 公共卫生相关性：先进的小动物超声影像学允许非侵入性组织成像，从而在研究方法中进行了巨大的完善，这也可以减少所使用的动物数量。 AAB心血管研究所拥有一项既定的超声研究计划，该计划将充分利用Visualsics Vevo 2100（一种新的最先进的工具）。在将超声成像扩展到整个罗切斯特大学医学中心的成本效益，现有仪器将被升级并迁移到主要的医疗中心校园，从而改变心血管研究和癌症，肌肉骨骼疾病，淋巴功能障碍和胎儿畸形的现有研究计划。