Light on a nanoscale: channelling energy through space and time to control neuronal activity

纳米级的光：通过空间和时间引导能量来控制神经元活动

• 批准号: DP140104458
• 负责人: Prof Judith Dawes
• 金额: $ 28.31万
• 依托单位: Macquarie University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP140104458
• 关键词: Light; nanoscale; channelling; energy; through

Quantum-mechanical effects of energy transfer and resonance will be harnessed to yield ultrabright nanoscale light sources. Research will unveil the intricate interplay between energy harvesting, transferring and emitting centres designed so that the flow of energy exhibits a directed character. This focussed intense energy will produce abundant visible photons from infrared light. Genetically engineered cells able to be stimulated optically by using an optogenetics method will be illuminated by our nanoscale light causing modulation of cell activity. This new capability will enable remote control of neuronal activity in specific circuits within the nervous system without the limitation of surgically inserted optical fibres.

能量转移和共振的量子力学效应将被利用来产生超亮纳米级光源。研究将揭示能源收集、转移和发射中心之间的复杂相互作用，这些中心的设计使能量流动呈现出定向特征。这种聚焦的强烈能量将从红外光中产生大量的可见光子。能够通过使用光遗传学方法进行光学刺激的基因工程细胞将被我们的纳米级光照亮，从而调节细胞活动。这一新能力将使远程控制神经系统内特定回路中的神经元活动成为可能，而不受通过手术插入的光纤的限制。