Dual nanoparticles to distinguish between right and left biomolecules

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This project aims to enhance the sensitivity of optical activity to ultralow molecular concentration samples. Optical activity is a commercially available technique used to distinguish chemically identical and morphologically different biomolecules (enantiomers). Unlike other scattering techniques, near-field enhancing of optical activity has not been achieved, thus limiting these measurements to high molecular concentrations. There is evidence indicating that optical activity can be enhanced using dual nanoparticles (ie small particles with the same response to electric and magnetic fields). This project aims to advance our understanding of these dual nanoparticles and experimentally implement their use to enhance optical activity.