Molecular Mechanisms of Malaria Parasite Entry

疟疾寄生虫进入的分子机制

• 批准号: nhmrc : 1143187
• 负责人: Dr Wai-Hong Tham
• 金额: $ 41.21万
• 依托单位: The Walter and Eliza Hall Institute of Medical Research
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-01-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/molecular-mechanisms-malaria-parasite-entry/1319893
• 关键词: Molecular; Mechanisms; Malaria; Parasite; Entry

Plasmodium vivax is a parasite that invades the youngest of human red blood cells. Our work will reveal how this malaria parasite enters our blood cells and the molecular mechanisms that allows successful invasion. This proposal will redefine our understanding of P. vivax invasion and explore novel ways to block its entry into red blood cells and therefore prevent malaria infection.

间日疟原虫是一种寄生虫，它入侵人类最年轻的红细胞。我们的工作将揭示这种疟疾寄生虫是如何进入我们的血细胞的，以及允许成功入侵的分子机制。这项提议将重新定义我们对间日疟原虫入侵的理解，并探索阻止其进入红细胞从而预防疟疾感染的新方法。