Boston-Area Research Training Program in Biomedical Informatics

描述（由申请人提供）：这份哈佛信息学培训计划（HITP）的提案认识到，生物医学信息学领域对于医学和健康科学研究来说，即使不是必不可少的，也是越来越相关的。因此，本提案的主要目的是为生物医学信息学领域训练有素的独立和成功的研究人员做出贡献。哈佛符合当前国家医学图书馆（NLM） RFA的所有要求，该RFA侧重于与健康相关的应用领域直接相关的基本信息学领域。我们的研究实验室的广度和深度，现实世界的临床系统，研究活动，正式的学术课程，和经验丰富的教师提供了一个优秀的环境，指导和指导学员在所有四个nlm确定的重点领域-医疗保健/临床信息学，转化生物信息学，临床研究信息学和公共卫生信息学。受训者不仅在课堂环境中，而且通过在实验室研究环境中的直接经验，接受基础信息学方法和每个重点领域的深入培训。

DESCRIPTION (provided by applicant): This proposal for the Harvard Informatics Training Program (HITP) recognizes that the field of biomedical informatics is an increasingly relevant, if not essential, field for medicine and research in the health sciences. As such, the primary aim of this proposal is to contribute to the cadre of highly-trained independent and successful researchers in the field of biomedical informatics. Harvard meets all requirements of the current National Library of Medicine (NLM) RFA, which focuses on those basic informatics areas that directly pertain to health-related application domains. The breadth and depth of our research laboratories, real-world clinical systems, research activities, formal academic programs, and experienced faculty provide an outstanding environment to mentor and instruct trainees in all four of the NLM-identified focus areas - healthcare/clinical informatics, translational bioinformatics, clinical research informatics, and public health informatics. Trainees receive in-depth training in foundational informatics methodologies and in each of the focus areas not only in the classroom setting but also through direct experience in the laboratory research setting. Our proposal builds on the strengths of our many years of NLM fellowship training and extends and improves our successful program through three innovations that considerably enhance the program. The HITP program 1) consolidates all of the major Harvard informatics laboratories under the umbrella of the Harvard Center for Biomedical Informatics (CBMI), centrally located on the Harvard Medical School campus, with dedicated space for HITP activities; 2) includes a research seminar - required of all trainees each semester throughout their training - that is a focal point for sustained interactions among all HITP trainees and mentors, regardless of their laboratory setting; 3) provides foundational academic training through the newly established Harvard Medical School Master in Medical Science (MMSc) in Biomedical Informatics. We request support for fifteen NLM trainees each year, 12 at the postdoctoral level and 3 at the predoctoral level. The formal academic component includes the Harvard MMSc for all postdoctoral trainees, and the PhD degree through the MIT Department of Electrical Engineering and Computer Science, with which the Harvard training program has been fully integrated for many years. The HITP program consists of four interrelated components: 1) formal coursework, 2) research mentorship, 3) thesis project, 4) mentored research grant. Trainees' overall progression throughout the training period is closely monitored. Trainees are regularly evaluated through their course work and through progress on their research projects. Progress on the thesis is ensured by the thesis committee, and trainees are regularly encouraged to submit papers for publication.