Curricular and Pedagogical Innovations in Quantitative Biology

说明申请的广泛、长期目标和具体目标，并提及 该项目（即，与原子能机构的使命相关）。简要描述研究设计和实现这些目标的方法。描述 你将用来追求这些目标的基本原理和技术。 此外，用两三句话，用通俗的语言描述这项研究与公共卫生的相关性。如果申请得到资助， 这样的描述将成为公开信息。因此，不包括专有/机密信息。不要超过空间 提供了 目前的本科生物科学课程没有提供足够的计算/定量 为有兴趣从事生物医学研究的学生提供培训。亨特学院 纽约将通过扩大和实施 生物学和相关科学的课程改革始于其第一阶段项目， 定量生物学（QuBi）倡议。Qu Bi的跨学科教师小组的第一个目标将整合 计算和定量生物学内容纳入26个不同的课程，为大约6500人提供服务。 生物学、化学、计算机科学、数学和统计学每年的注册人数 部门其中一些修改后的课程将向我们的本科生介绍以下领域： Qu Bi预计，每年将有多达20名学生攻读新的生物信息学 在第一阶段期间开发的备选方案和浓度。曲壁的第二个目标是建立一个持久的 通过培训我们的科学教师，培养亨特的定量生物学家的教育基础设施， 新的教学方法，如以问题为基础的学习（PBL），合作课程开发， 协作教学我们的教师将参加教育会议，并参加夏季研讨会 由教育专家管理。在这一举措中获得的所有知识将与教师分享 猎人Qu Bi的第三个目标是建立一个临界质量的定量生物学学生，这对成功的 第二阶段项目。Qu Bi团队将与学院现有的成功的科学相关的 教育计划（MARC，MBRS/RISE，HHMI，NSF CSEMS和CollegeNow）为学生提供服务， 无论是高中还是大学。亨特大学拟议的课程改革的成功 大学将在增加定量训练生物学家的数量方面产生重大影响-特别是 少数民族科学家-在猎人和整个城市大学，因为猎人课程活动将与 其他CUNY校园 与公共卫生相关。当今可用的生物信息量，如人类基因组 序列和健康统计数据呈指数级增长。计算科学和定量科学是 因此在疾病预防和治疗中发挥着越来越重要的作用。拟建项目 将培养出具有生物医学研究所需定量技能的未来一代科学家， 21世纪。 性能

State the application's broad, long-term objectives and specific aims, making reference to the health relatedness of the project (i.e., relevance to the mission of the agency). Describe concisely the research design and methods for achieving these goals. Describe the rationale and techniques you will use to pursue these goals. In addition, in two or three sentences, describe in plain, lay language the relevance of this research to public health. If the application is funded, this description, as is, will become public information. Therefore, do not include proprietary/confidential information. DO NOT EXCEED THE SPACE PROVIDED. Current undergraduate biological sciences curricula do not provide adequate computational/quantitative training for students who are interested in pursuing a career in biomedical research. Hunter College of the City University of New York (CUNY) will address this lack of training by broadening and implementing a curricular transformation in biology and related sciences begun during its Phase I project, named the Quantitative Biology (QuBi) initiative. QuBi's interdisciplinary faculty panel's first aim will integrate computational and quantitative biology content into 26 different courses serving approximately 6,500 registrants per year across the Biology, Chemistry, Computer Science, Mathematics and Statistics departments. Several of these modified courses will introduce our undergraduates to the field of bioinformatics, and QuBi anticipates that up to 20 students per year will pursue the new bioinformatics options and concentrations developed during Phase I. QuBi's second aim is to establish an enduring educational infrastructure for producing quantitative biologists at Hunter by training our science faculty in new pedagogical approaches such as problem-based learning (PBL), collaborative course development and collaborative teaching. Our faculty will attend educational conferences and participate in summer workshops run by pedagogical experts. All knowledge acquired during this initiative will be shared with faculty across Hunter. QuBi's third aim, to build a critical mass of quantitative biology students, is vital for the success of the Phase II project. The QuBi team will collaborate with the College's existing successful science-related educational programs (MARC, MBRS/RISE, HHMI, NSF CSEMS and CollegeNow) for student outreach at both the high school and the college level. The success of the proposed curricular transformation at Hunter College will have a major impact in increasing the number of quantitatively trained biologists - especially minority scientists - at Hunter and across CUNY, since the Hunter curricular activities will be shared with other CUNY campuses. Relevance to Public Health. The amount of biological information available today, such as human genome sequences and health statistics, is increasing exponentially. The computational and quantitative sciences are therefore playing an increasingly important role in disease prevention and treatment. The proposed project will produce a future generation of scientists with the quantitative skills required for biomedical research in the 21st century. PERFORMANCE