Improving Adherence to Recommended Surveillance in Breast Cancer Survivors

提高乳腺癌幸存者对建议监测的遵守率

• 批准号: 7989522
• 负责人: REBECCA A SHELBY
• 金额: $ 15.54万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-01 至 2015-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7989522
• 关键词: Address; Adherence; African American; Aftercare; Behavior; Behavioral; Breast; Cancer Control; Cancer Survivor; Caring; Cognition; Cognitive; Communication; Communities; Community Hospitals; Cues; Data; Development Plans; Distress; Early Diagnosis; Educational Materials; Educational workshop; Effectiveness; Emotional; Emotions; Endometrial Carcinoma; Focus Groups; Fright; Funding; Goals; Gynecologic; Health Professional; Health education; Informal Social Control; Intervention; Interview; Malignant Neoplasms; Mammography; Manuals; Medical; Medical Records; Modification; Participant; Patients; Physical Examination; Pilot Projects; Printing; Procedures; Process; Protocols documentation; Provider; Psychological reinforcement; Questionnaires; Randomized; Recruitment Activity; Recurrence; Reporting; Research; Research Training; Risk; Schedule; Screening for cancer; Self Efficacy; Tamoxifen; Testing; Time; Training; Woman; base; cancer recurrence; career development; design; dissemination research; efficacy testing; evidence based guidelines; follow-up; improved; innovation; literacy; malignant breast neoplasm; mortality; outreach; programs; protocol development; randomized trial; skills; social; survivorship; therapy development; treatment as usual

DESCRIPTION (provided by applicant): Evidence-based guidelines recommend four cancer surveillance procedures for breast cancer survivors: physical examination, mammography, breast self-exam (BSE), and gynecologic follow-up. The early detection of recurrent and new cancers can best be achieved through the combined, on schedule use of these four key surveillance procedures. Yet, data suggest that up to 55% of breast cancer survivors do not undergo these four procedures as recommended. This application proposes a program of research and training focused on improving adherence to recommended surveillance in breast cancer survivors, with an emphasis on the recruitment and retention of African American breast cancer survivors. The proposed research includes two studies. Study 1 will develop an Improving Adherence intervention protocol that targets the cognitive, emotional, and behavioral factors that contribute to sustained adherence for each of the four recommended cancer surveillance procedures. Study 1 also seeks to develop the assessment protocol that will be used to evaluate this intervention. Study 2 will test the Improving Adherence intervention protocol developed in Study 1 in a pilot randomized trial. Participants will be recruited from four community hospitals. In Study 1, cognitive interviews will be conducted with 30 breast cancer survivors to pilot and refine the assessment materials. To develop the Improving Adherence intervention protocol, eight focus groups will be conducted with breast cancer survivors (8 women per group), two focus groups with health professionals (8 per group), and one focus group with eight African American women who conduct cancer-related educational outreach in the community. Focus groups will be used to develop the intervention manual and accompanying participant materials. Study 2 will conduct a pilot randomized test of the Improving Adherence protocol; 106 breast cancer survivors who have been non-adherent to physical exam, mammography, or gynecologic follow-up will be randomly assigned to: 1) the Improving Adherence protocol, or 2) usual care with printed educational materials. Assessments will be conducted pre- and post-treatment. Subsequent adherence to surveillance will be assessed via medical record review 15 months after the intervention. The proposed studies have the potential to provide valuable, new information that can aid in selecting strategies for helping breast cancer survivors better adhere to recommended surveillance. The career development plan proposed in this application focuses on training in cancer control and survivorship, intervention development and testing, and effectiveness and dissemination research. Through a combination of coursework, seminars, and workshops, the applicant will develop the necessary skills for building an independently funded program of research focused on rigorously evaluating and disseminating interventions that can increase adherence to recommended care in cancer survivors.

描述（由申请人提供）：基于证据的指南建议对乳腺癌幸存者进行四种癌症监测程序：体检、乳房X光检查、乳房自检（BSE）和妇科随访。通过按计划联合使用这四种关键监测程序，可以最好地实现复发性癌症和新发癌症的早期发现。然而，数据表明，高达 55% 的乳腺癌幸存者没有按照建议接受这四种手术。该申请提出了一项研究和培训计划，重点是提高乳腺癌幸存者对建议监测的依从性，重点是招募和保留非裔美国乳腺癌幸存者。拟议的研究包括两项研究。研究 1 将制定一项改善依从性干预方案，该方案针对有助于持续依从四种推荐的癌症监测程序中的每一种的认知、情感和行为因素。研究 1 还寻求制定用于评估这种干预措施的评估方案。研究 2 将在一项试点随机试验中测试研究 1 中开发的改善依从性干预方案。参与者将从四家社区医院招募。在研究 1 中，将对 30 名乳腺癌幸存者进行认知访谈，以试点和完善评估材料。为了制定改善依从性干预方案，将由八个由乳腺癌幸存者（每组 8 名女性）组成的焦点小组、由卫生专业人员组成的两个焦点小组（每组 8 名）以及由 8 名非裔美国妇女组成的焦点小组组成，她们在社区中开展与癌症相关的教育外展活动。将利用焦点小组来制定干预手册和随附​​的参与者材料。研究2将对改善依从性方案进行试点随机测试； 106 名不遵守体检、乳房 X 光检查或妇科随访的乳腺癌幸存者将被随机分配到：1) 改善依从性方案，或 2) 使用印刷教育材料进行常规护理。将在治疗前和治疗后进行评估。随后的监测依从性将通过干预后 15 个月的病历审查进行评估。拟议的研究有可能提供有价值的新信息，有助于选择帮助乳腺癌幸存者更好地遵守建议的监测的策略。本申请中提出的职业发展计划侧重于癌症控制和生存、干预开发和测试以及有效性和传播研究方面的培训。通过课程作业、研讨会和讲习班的结合，申请人将培养建立独立资助的研究计划所需的技能，该计划的重点是严格评估和传播可以提高癌症幸存者对推荐护理的依从性的干预措施。