Neurological Emergencies Treatment Trials (NETT) Network Clinical Site Hubs (U10)
神经急症治疗试验 (NETT) 网络临床站点中心 (U10)
基本信息
- 批准号:7924227
- 负责人:
- 金额:$ 19.41万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2007
- 资助国家:美国
- 起止时间:2007-09-30 至 2012-08-31
- 项目状态:已结题
- 来源:
- 关键词:Accident and Emergency departmentAcuteAdultAmbulancesCaringCessation of lifeClinical ResearchClinical TrialsCollaborationsCommunicationCommunity HospitalsComplementConduct Clinical TrialsElementsEmergency CareEmergency MedicineEmergency SituationEmergency medical serviceEmergency treatmentEnvironmentEpilepsyEvaluation ResearchEvolutionFutureGrantHealthcareHelicopterHospitalizationHospitalsHuman ResourcesInjuryInstitutesInstitutionInternetIntubationJointsKnowledgeLawsLeadLeadershipLearningLicensingLinkMarylandMedicalMedical centerMedicineMethodsMissionNational Institute of Neurological Disorders and StrokeNerve TissueNervous system structureNeurologicNeurological emergenciesNeurologistNeurologyNeurosurgeonPatient CarePatient RecruitmentsPatientsPediatricsPhase III Clinical TrialsPhysical MedicinePhysiciansPrevention programPrincipal InvestigatorProtocols documentationRecording of previous eventsRecoveryRegulationRelative (related person)Request for ApplicationsResearchResearch InfrastructureResourcesRuralSeizuresServicesStrokeStructureSystemTechnologyTrainingTransportationTraumaUniversitiesVisionWorkclinical research sitedisabilityinterestmedical specialtiesmultidisciplinarynervous system disorderneurosurgerynovel strategiesoperationpediatric traumaprogramspublic educationresponsesuburbsuccesstreatment trial
项目摘要
DESCRIPTION (provided by applicant): The specific objectives of this application are to: (1) create a clinical research network of emergency medicine physicians, neurologists, and neurosurgeons that will work together to develop in an efficient manner more and better treatments for patients with acute neurological disorders through execution of NINDS-sponsored clinical trials. And (2) conduct two large, streamlined phase III clinical trials involving neurological emergencies to demonstrate the capability of the Network and to stimulate general interest in the NETT Network regarding future collaborations. We have brought together an interdisciplinary group expert in clinical trials management and neurologic emergencies from the robust expertise available at the University of Maryland and the Johns Hopkins University and have created a partnership with 9 community hospitals in rural, urban, and suburban settings. Our Clinical Site (consortium) Hub (CSH) leadership includes a neurologist and 3 emergency medicine physicians. Representation in the CSH includes experts in epilepsy, adult and pediatric trauma medicine, stroke, neurosurgery, neurointensive care, Neuroradiology, physiatry, and pediatrics. In the future, depending on the clinical trials in progress, representation in the CSH can vary as to the experts involved and relative effort on behalf of network activities. The CSH leadership will also work closely with the Maryland Institute for Emergency Medical Services Systems (MIEMSS) to effect pre-hospital protocols, as needed for the clinical trials to be conducted. The CSH is partnering with emergency medicine spoke principal investigators. The CSH leadership will support the hub and spoke research teams in their patient recruitment and management efforts as well as for their administrative needs. Communication amongst the hubs and spokes of our network will be promoted using a variety of methods, including efforts to fully utilize the internet and related broadband technologies. CSH leadership will work diligently to complement the activities of the NETT Network leadership to create a State of Maryland emergency research enterprise that will contribute to the objectives and success of the NETT Network and benefit our clinical trial patients. Ultimately the delivery of day to day emergent neurological care throughout the State will be enhanced and the lessons learned from the NETT Network research enterprise may benefit the delivery of emergency care statewide.
描述(由申请人提供):本申请的具体目标是:(1)建立一个由急诊内科医生、神经科医生和神经外科医生组成的临床研究网络,通过执行nind资助的临床试验,共同努力,以有效的方式为急性神经系统疾病患者开发更多更好的治疗方法。(2)开展两项涉及神经紧急情况的大型精简III期临床试验,以证明该网络的能力,并激发人们对NETT网络未来合作的普遍兴趣。我们汇集了来自马里兰大学和约翰霍普金斯大学的临床试验管理和神经急救方面的跨学科专家,并与农村、城市和郊区的9家社区医院建立了合作关系。我们的临床中心(联盟)中心(CSH)领导包括一名神经科医生和三名急诊医生。CSH的代表包括癫痫、成人和儿童创伤医学、中风、神经外科、神经重症监护、神经放射学、物理学和儿科方面的专家。在未来,根据正在进行的临床试验,CSH中的代表可能会因参与的专家和代表网络活动的相对努力而有所不同。CSH的领导层还将与马里兰紧急医疗服务系统研究所(MIEMSS)密切合作,根据临床试验的需要,制定院前协议。CSH正在与急诊医学首席研究人员合作。CSH领导将支持中心和辐条研究团队的患者招募和管理工作以及他们的行政需求。我们将通过多种方式促进网络枢纽和辐条之间的通信,包括努力充分利用互联网和相关宽带技术。CSH领导层将努力补充NETT网络领导层的活动,以创建马里兰州紧急研究企业,这将有助于NETT网络的目标和成功,并使我们的临床试验患者受益。最终,在全州范围内提供的日常紧急神经系统护理将得到加强,从全国神经网络研究事业中吸取的经验教训可能有利于在全州范围内提供紧急护理。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Barney Joel Stern其他文献
Barney Joel Stern的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Barney Joel Stern', 18)}}的其他基金
Neurological Emergencies Treatment Trials (NETT) Network Clinical Site Hubs (U10)
神经急症治疗试验 (NETT) 网络临床站点中心 (U10)
- 批准号:
7676770 - 财政年份:2007
- 资助金额:
$ 19.41万 - 项目类别:
Neurological Emergencies Treatment Trials (NETT) Network Clinical Site Hubs (U10)
神经急症治疗试验 (NETT) 网络临床站点中心 (U10)
- 批准号:
8130581 - 财政年份:2007
- 资助金额:
$ 19.41万 - 项目类别:
Neurological Emergencies Treatment Trials (NETT) Network Clinical Site Hubs (U10)
神经急症治疗试验 (NETT) 网络临床站点中心 (U10)
- 批准号:
7255236 - 财政年份:2007
- 资助金额:
$ 19.41万 - 项目类别:
Neurological Emergencies Treatment Trials (NETT) Network Clinical Site Hubs (U10)
神经急症治疗试验 (NETT) 网络临床站点中心 (U10)
- 批准号:
7503417 - 财政年份:2007
- 资助金额:
$ 19.41万 - 项目类别:
相似海外基金
Un/kindness, shame & resistance: the care of inpatients in NHS adult acute mental health units and how it might be improved
Un/善良,羞耻
- 批准号:
2885806 - 财政年份:2023
- 资助金额:
$ 19.41万 - 项目类别:
Studentship
Post-Acute Care Transitions for Older Adult Medicare Beneficiaries with Serious Mental Illness
患有严重精神疾病的老年医疗保险受益人的急性后护理过渡
- 批准号:
10772386 - 财政年份:2023
- 资助金额:
$ 19.41万 - 项目类别:
Paving The Way to a Canadian Standard of Care with CAR-T Cellular Therapy: Phase II Trial of CD19 CAR-T for Relapsed/Refractory Adult Acute Lymphoblastic Leukemia (CLIC-01A)
通过 CAR-T 细胞疗法为加拿大护理标准铺平道路:CD19 CAR-T 治疗复发/难治性成人急性淋巴细胞白血病的 II 期试验 (CLIC-01A)
- 批准号:
474619 - 财政年份:2022
- 资助金额:
$ 19.41万 - 项目类别:
Operating Grants
Investigating the impact acute inhalation of cannabis with a high content of delta-9-tetrahydrocannabinol has on myelination and microglia in adult and aged mice
研究急性吸入高含量 delta-9-四氢大麻酚的大麻对成年和老年小鼠髓鞘形成和小胶质细胞的影响
- 批准号:
485965 - 财政年份:2022
- 资助金额:
$ 19.41万 - 项目类别:
Studentship Programs
Paving The Way to a Canadian Standard of Care with CAR-T Cellular Therapy: Phase II Trial of CD19 CAR-T for Relapsed/Refractory Adult Acute Lymphoblastic Leukemia (CLIC-01A)
通过 CAR-T 细胞疗法为加拿大护理标准铺平道路:CD19 CAR-T 治疗复发/难治性成人急性淋巴细胞白血病的 II 期试验 (CLIC-01A)
- 批准号:
466358 - 财政年份:2022
- 资助金额:
$ 19.41万 - 项目类别:
Operating Grants
Metabolomics for prediction of cisplatin mediated acute kidney injury: a Canadian multi-centre adult and pediatric study
预测顺铂介导的急性肾损伤的代谢组学:加拿大多中心成人和儿童研究
- 批准号:
402040 - 财政年份:2019
- 资助金额:
$ 19.41万 - 项目类别:
Operating Grants
Study of pathogenic mechanism of age-dependent chromosome translocation in adult acute lymphoblastic leukemia
成人急性淋巴细胞白血病年龄依赖性染色体易位发病机制研究
- 批准号:
18K16103 - 财政年份:2018
- 资助金额:
$ 19.41万 - 项目类别:
Grant-in-Aid for Early-Career Scientists
Causal effect of time-varying driving pressures on mortality in mechanically ventilated, adult patients with acute respiratory distress syndrome
时变驱动压力对机械通气成年急性呼吸窘迫综合征患者死亡率的因果影响
- 批准号:
377313 - 财政年份:2017
- 资助金额:
$ 19.41万 - 项目类别:
Studentship Programs
Role of SETBP1 in adult Ph+ acute lymphoblastic leukemia
SETBP1 在成人 Ph 急性淋巴细胞白血病中的作用
- 批准号:
9315111 - 财政年份:2016
- 资助金额:
$ 19.41万 - 项目类别:
Acute Inhibition of Adult-born Granule Cells and its Effect on Antidepressant Act
成体颗粒细胞的急性抑制及其抗抑郁作用
- 批准号:
8734273 - 财政年份:2013
- 资助金额:
$ 19.41万 - 项目类别: