UCLA Older Americans Independence Center

加州大学洛杉矶分校克劳德·佩珀老年美国人独立中心（OAIC）旨在促进旨在保持和恢复老年人独立性的研究。通过其主题的翻译研究，以保持独立性，加州大学洛杉矶分校OAlC的研究范围从T1到T2翻译研究的全方位。在这个主题中，UCLA OAIC的一个重要重点是开发和理解减少炎症的干预措施。 为了实现其目标，UCLA OAIC已经建立了4个研究核心（招募和保留，研究运营，分析和成本效益，以及炎症生物学）和一个新的信息传播核心，这将促进OAIC相关研究的每一步（招募，测量，数据管理，分析，解释和采用结果）。研究核心在4个层面提供支持： 咨询（例如，提供长达数小时的建议，阅读论文或提案） 短期（例如，长达几天的咨询，进行分析） 持续或长期支持（例如，正在进行，项目小组的一部分） 关于新提案的伙伴关系 此外，加州大学洛杉矶分校的OAIC试点和探索性研究核心和研究职业发展核心通过初级研究人员和试点奖励的管道刺激新的研究，并招募成功的研究人员进入OAIC相关的研究。该中心的一个具体目标是创建翻译研究人员团队，并在进行研究的原则，桥梁基础，临床和卫生服务/传播研究培训初级教师。领导/行政核心确保完成这些具体活动，并以最佳方式实现UCLA OAIC的目标。 通过OAIC集中精力和资源，可以加快研究开发、测试和传播有前途的创新以保持独立性的时间轴。在5年周期结束时，UCLA OAIC将成为从基础科学延伸到临床实践和政策的转化研究的典范计划，并将创造出一代新的研究人员，他们可以开始在这一主题中发挥领导作用。

The UCLA Claude Pepper Older Americans Independence Center (OAIC) is designed to promote research aimed at maintaining and restoring the independence of older persons. Through its theme of Translational Research to Maintain Independence, the UCLA OAlC's research extends across the full spectrum from T1 to T2 translational research. Within this theme, an important focus of the UCLA OAIC is on developing and understanding interventions that reduce inflammation. To accomplish its goals, the UCLA OAIC has established 4 Research Cores (Recruitment and Retention, Research Operations, Analysis and Cost Effectiveness, and Inflammatory Biology) and a new Information Dissemination Core that will facilitate OAlC-related research at every step (recruitment, measurement, data management, analysis, interpretation, and adoption of findings). Research cores provide support at 4 levels: Consultation (e.g., providing up to several hours of advice, reading a paper or a proposal) Short-term (e.g., up to a couple days of consultation, performing assays) Ongoing or long-term support (e.g., ongoing, part of the project team) Partnership on new proposals In addition, the UCLA OAIC Pilot and Exploratory Studies Core and Research Career Development Core stimulate new research via a pipeline of junior investigators and pilot awards and recruit successful investigators into OAlC-related research. A specific goal of the Center is to create teams of translational researchers and to train junior faculty in the principles of conducting research that bridges basic, clinical, and health services/dissemination research. The Leadership/Administrative Core ensures that these specific activities are accomplished and the goals of the UCLA OAIC are optimally achieved. By focusing efforts and resources through the OAIC, the timeline for research to develop, test, and disseminate promising innovations to maintain independence can be accelerated. At the end ofthe 5-year cycle, the UCLA OAIC will be a model program for translational research extending from basic science to clinical practice and policy and will have created a generation of new researchers who can begin to assume leadership in this theme.