9th International Podocyte Conference
9th International Podocyte Conference
批准号:
8317085
负责人:
Stuart James Shankland
金额:
$1.3万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2012
资助国家:
美国
项目状态:
已结题
起止时间:
2012-04-05 至 2013-03-31
关键词:
AccountingActininActinsAdherens JunctionAdultAlbuminsApplications GrantsBasement membraneBiologyBlood capillariesBowman&aposs spaceCD29 AntigenCaliberCardiovascular DiseasesCellsCharacteristicsChargeChildChronicClinicalClinical ResearchComplexContractile ProteinsContractile SystemDetectionDevelopmentDiabetes MellitusDiagnosisDiseaseEndothelial CellsEpithelial CellsEpitheliumFibroblastsFinancial SupportFocal AdhesionsFocal Segmental GlomerulosclerosisFoot ProcessGlomerular capsule structureGlycocalyxGoalsIncidenceInjuryInjury to KidneyIntercellular JunctionsInternationalKidneyKidney DiseasesKnowledgeLeftLiteratureMembranous GlomerulonephritisMicrofilamentsMinorMorbidity - disease rateMyosin Type IINPHS2 proteinNephrotic SyndromeP-CadherinParietalPatientsPericytesPhenotypePrevalenceProteinsProteinuriaRenal glomerular diseaseReportingResearchRisk FactorsSeveritiesSeverity of illnessShapesStructureSyndromeTalinUnited States National Institutes of HealthVinculinVisceralWritingburden of illnesscapillarycell typeglomerular basement membraneimprovedinjury and repairkidney epithelial cellmacromoleculemeetingsmesangial cellmortalitynephrinneuronal cell bodyoutcome forecastpodocytepreventrepairedslit diaphragmsymposiumsynaptopodin
中文摘要
点击翻译按钮获取中文摘要
英文摘要
DESCRIPTION (provided by applicant): The glomerular podocyte is a terminally differentiated and highly specialized kidney epithelial cell. In addition to providing structural support to the glomerulus, its main function is to limit the passage of protein from the intravascular space to the urinary space. Thus, the clinical signature of injury to podocytes is proteinuria. Injury occur in diabetes, membranous nephropathy, focal segmental glomerulosclerosis and minimal change disease. This R13 applicant application is written to support the the 9th International Podocyte Conference, the major goal of which is to substantially advance the clinical and research aspects of podocyte diseases.
PUBLIC HEALTH RELEVANCE: Injury to kidney podocytes is the leading cause of proteinuria, which is an independent risk factor for cardiovascular disease. Improving our understanding of injury and repair will reduce the overall burden of disease.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
The Intersection of Podocyte Disease and Aging
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批准号:10733868
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项目类别:
-
资助金额:$76.29万
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财政年份:2023
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负责人:Stuart James Shankland
-
依托单位:
Targeting Podocyte-Endothelial Cell Crosstalk as a FSGS Therapy
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批准号:10635547
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项目类别:
-
资助金额:$77.52万
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财政年份:2023
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负责人:Stuart James Shankland
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依托单位:
Autocrine and paracrine podocyte signals decrease glomerular function/health in aged kidneys
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批准号:10698100
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项目类别:
-
资助金额:$73.57万
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财政年份:2022
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负责人:Stuart James Shankland
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依托单位:
Kidney Aging Impairs Progenitor and Endocrine Function
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批准号:10549835
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项目类别:
-
资助金额:$60.87万
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财政年份:2020
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负责人:Stuart James Shankland
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依托单位:
Kidney Aging Impairs Progenitor and Endocrine Function
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批准号:10341118
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项目类别:
-
资助金额:$61.83万
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财政年份:2020
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负责人:Stuart James Shankland
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依托单位:
Cell specific delivery of novel therapies to enhance glomerular regeneration and repair
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批准号:10675681
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项目类别:
-
资助金额:$81.62万
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财政年份:2020
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负责人:Stuart James Shankland
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依托单位:
Cell specific delivery of novel therapies to enhance glomerular regeneration and repair
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批准号:10247521
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项目类别:
-
资助金额:$81.62万
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财政年份:2020
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负责人:Stuart James Shankland
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依托单位:
Cell specific delivery of novel therapies to enhance glomerular regeneration and repair
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批准号:10414816
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项目类别:
-
资助金额:$81.62万
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财政年份:2020
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负责人:Stuart James Shankland
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依托单位:
Reduced Glomerular Progenitors Impair Regeneration in Aged Kidney
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批准号:9329346
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项目类别:
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资助金额:$47.2万
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财政年份:2016
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负责人:Stuart James Shankland
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依托单位:
Rebuilding the glomerular filtration barrier by regenerating adult podocytes
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批准号:9564892
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项目类别:
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资助金额:$42.92万
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财政年份:2015
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负责人:Stuart James Shankland
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依托单位:
Juxta-glomerular cells serve as glomerular epithelial cell progenitors in glomerular disease
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批准号:10436216
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项目类别:
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资助金额:$59.33万
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财政年份:2014
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负责人:Stuart James Shankland
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依托单位:
Juxta-glomerular cells serve as glomerular epithelial cell progenitors in glomerular disease
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批准号:9816246
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项目类别:
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资助金额:$62.07万
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财政年份:2014
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负责人:Stuart James Shankland
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依托单位:
Juxta-glomerular cells serve as glomerular epithelial cell progenitors in glomerular disease
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批准号:10189566
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项目类别:
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资助金额:$59.67万
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财政年份:2014
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负责人:Stuart James Shankland
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依托单位:
Pericyte-endothelial cross talk in vascular stability after kidney injury
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批准号:8705506
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项目类别:
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资助金额:$49.92万
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财政年份:2012
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负责人:Stuart James Shankland
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依托单位:
Pericyte-endothelial cross talk in vascular stability after kidney injury
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批准号:8539599
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项目类别:
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资助金额:$49.34万
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财政年份:2012
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负责人:Stuart James Shankland
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依托单位:
Pericyte-endothelial cross talk in vascular stability after kidney injury
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批准号:8890141
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项目类别:
-
资助金额:$49.67万
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财政年份:2012
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负责人:Stuart James Shankland
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依托单位:
The role of Macrophage Delivered WNT Signaling in kidney injury and repair
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批准号:8466959
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项目类别:
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资助金额:$34.15万
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财政年份:2009
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负责人:Stuart James Shankland
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依托单位:
Cell Cycle and Podocyte Apoptosis
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批准号:7921100
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项目类别:
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资助金额:$8.58万
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财政年份:2009
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负责人:Stuart James Shankland
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依托单位:
New Thoughts on Parietal Epithelial Cells
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批准号:7739904
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项目类别:
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资助金额:$23.4万
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财政年份:2009
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负责人:Stuart James Shankland
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依托单位:
New Thoughts on Parietal Epithelial Cells
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批准号:7912886
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项目类别:
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资助金额:$19.5万
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财政年份:2009
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负责人:Stuart James Shankland
-
依托单位:
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