Mentoring Behavioral Scientists for Career Development in Pediatric T1D Research

描述（由申请人提供）：为响应RFA-DK-028“行为科学家糖尿病研究职业发展计划（K12）”，并考虑到目前在1型糖尿病（T1D）研究中缺乏资深行为科学家来指导年轻的研究人员，结合贝勒医学院（BCM）儿科无与伦比的教师、研究和患者资源，我们热情地将此提案提交给BCM指导行为科学家在儿科1型糖尿病（T1D）研究中的职业发展。这个职业发展项目的目的是为博士后和早期职业行为研究者（“学者”）创建一个跨学科和基于证据的项目。我们建议3名学者（2名博士后水平和1名早期职业水平），他们将在T1D行为研究中获得2- 3年的全面，教学指导的职业发展经验。该计划围绕三个目标建立：1)学者必须了解青少年和家庭的T1D“生活经验”，以促进临床知情的行为研究；2)学者将了解T1D的神经生物学，血糖波动与行为之间的密切相互作用，以及神经认知风险和弹性因素如何影响行为，执行功能和依从性；3)学者将展示基本的论文写作技巧。该计划要求掌握T1D神经生物学的核心教学和健康行为改变的理论/方法。根据学者之前的培训，映射到教学有机会在附近的优秀学术机构高级课程-德克萨斯大学公共卫生学院和休斯顿大学。学者将在资深行为科学家和资深儿科内分泌学家团队的指导下进行以下3个研究途径中的一个：1)神经心理学和风险因素筛查；2)基于家庭和系统的干预措施，优化血糖控制、依从性和生活质量，重点关注过渡年龄青年T1D患者；3)基于交互式技术的干预措施，以改善依从性和血糖控制。一个由贝勒大学高级教师组成的咨询委员会将评估该项目，并根据既定基准监督个别学者的进展。一个由资深科学家组成的外部顾问委员会也将提供反馈。我们的长期目标是创建一个全国认可的项目，培养在T1D行为研究领域获得成功和资助的科学家，他们最终将有能力在行为糖尿病研究中继承这一遗产。

DESCRIPTION (provided by applicant): In response to RFA-DK-028 "Career Development Programs in Diabetes Research for Behavioral Scientists (K12)" and given that currently there is a documented lack of senior behavioral scientists in type 1 diabetes (T1D) research to mentor younger investigators, combined with the unparalleled faculty, research, and patient resources in Pediatrics at Baylor College of Medicine (BCM), we enthusiastically submit this proposal for Mentoring Behavioral Scientists for Career Development in Pediatric Type 1 Diabetes (T1D) Research at BCM. The purpose of this career development program is to create an interdisciplinary and evidence-based program for postdoctoral and early-career behavioral investigators ["Scholars"]. We propose an initial program for 3 Scholars (two postdoctoral level and one early career level) who will receive a 2-to 3-year comprehensive, didactic mentored career development experience in T1D behavioral research. The program is built around three objectives: 1) Scholars must understand the 'lived experience' of T1D for youth and families to foster clinically-informed behavioral research; 2) Scholars will understand the neuro-biology of T1D, the close interplay between blood glucose fluctuations and behavior, and how neurocognitive risk and resilience factors impact behavior, executive functioning, and adherence; and 3) Scholars will demonstrate basic grant writing skills. The program requires mastery of core didactics in neuro-biology of T1D and theories/methods of health behavior change. Depending on Scholars' prior training, mapped on to the didactics are opportunities for advanced courses at outstanding academic institutions nearby--the University of Texas School of Public Health and the University of Houston. Scholars will be mentored by a team of senior behavioral scientist and senior pediatric endocrinologist in 1 of 3 research pathways: 1) neuropsychology and risk-factor screening; 2) family- and systems-based interventions to optimize glycemic control, adherence and quality of life outcomes with a focus on transition-age youth with T1D; and 3) interactive technology-based interventions to improve adherence and glycemic control. An Advisory Committee of Senior Baylor faculty will evaluate the program and monitor the progress of the individual Scholars against established benchmarks. An External Advisory Board of senior scientists will also provide feedback. Our long-term goal is to create a nationally-recognized program that produces scientists with successful and funded careers in T1D behavioral research, who will eventually be well-positioned to carry on this legacy of mentoring in behavioral diabetes research.