FASEB SRC on Liver Biology: Fundamental Mechanisms and Translational Applications

FASEB SRC 肝脏生物学：基本机制和转化应用

• 批准号: 8720321
• 负责人: GEORGE K MICHALOPOULOS
• 金额: $ 2.6万
• 依托单位: FEDERATION OF AMER SOC FOR EXPER BIOLOGY
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-06-01 至 2015-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8720321
• 关键词: American; Area; Basic Science; Biology; Clinical; Clinical Treatment; Collaborations; Colorado; Development; Diagnostic; Differentiation and Growth; Disease; Education; Ensure; Environment; Fostering; Gene Expression; Goals; Growth; Health; Hepatic; Hepatic Tissue; Hepatobiliary; Hepatocyte; International; Liver; Liver Fibrosis; Liver Stem Cell; Liver diseases; Malignant neoplasm of liver; Minority; Molecular Abnormality; Natural regeneration; Organogenesis; Participant; Patient Care; Regenerative Medicine; Regulation; Research; Research Personnel; Science; Scientist; Societies; Solutions; Staging; Therapeutic; Tissue Engineering; Translational Research; Translations; Transplantation; Woman; abstracting; career; liver injury; liver metabolism; meetings; novel; posters; preference; programs; public health relevance; success; symposium; tumor metabolism

DESCRIPTION (provided by applicant): The current application seeks partial support for the Federation of American Societies for Experimental Biology (FASEB) summer research conference on "Liver Biology: Fundamental Mechanisms and Translational Applications". For the past 20 years, this meeting has been held biennially and is now recognized as the world's premier conference covering all aspects of basic science research involving the liver. The conference will be held from July 6-11, 2014, in Keystone, Colorado. The main goals of the conference are to i) integrate the research advances offered by disparate areas of liver biology in order to foster new collaborative projects on both national and international scale, ii) encourage junior and early stage investigators, women and minority scientists to pursue liver research to ensure that the study of hepatic disease and biology remains vigorous and iii) accelerate translation of fundamental advances in liver biology into novel clinical treatments through the interactions of basic and clinical researchers. These goals will be achieved through specific programmatic strategies. The program is divided into nine major sessions and includes presentations from forty-seven invited speakers. In addition, these sessions will accommodate multiple short 'late-breaking' talks that will be chosen to represent the most significant and timey research advances in liver research. Preference will be given to junior, minority and women investigators. The program also provides two poster sessions for one-on-one dialogue and several additional opportunities for informal, yet intimate scientific exchange among speakers and attendees throughout the stay. Specific session topics include liver differentiation and organogenesis, regulation of hepatobiliary gene expression in health and disease, liver growth and regeneration, liver metabolism in health and disease, liver injury and hepatic fibrosis, liver disease due to genetic abnormalities, liver cancer, liver stem cells and implications in regenerative medicine and development, hepatocyte transplantation and hepatic tissue engineering and recent advances in basic and translational liver pathobiology. Emphasis is given to translational application of recent and current discoveries. Thus, the program integrates the most relevant and timely topics in basic and applied aspects of liver health and disease to promote scientific exchange, dissemination, education and collaboration and translation to patient care.

描述（由申请人提供）：目前的申请寻求对美国实验生物学学会联合会（FASEB）夏季研究会议“肝脏生物学：基础机制和转化应用”的部分支持。在过去的20年里，该会议每两年举行一次，现在被公认为世界上首屈一指的会议，涵盖涉及肝脏的基础科学研究的各个方面。会议将于2014年7月6日至11日在科罗拉多的Keystone举行。会议的主要目标是i）整合肝脏生物学不同领域提供的研究进展，以促进国家和国际规模的新合作项目，ii）鼓励初级和早期研究人员，妇女和少数民族科学家进行肝脏研究，以确保肝病和生物学研究保持活力，以及iii）通过基础和临床研究人员的相互作用，加速将肝脏生物学的基本进展转化为新的临床治疗方法。这些目标将通过具体的方案战略来实现。该计划分为九个主要会议，包括来自47位受邀演讲者的演讲。此外，这些会议将容纳多个简短的“最新”会谈，这些会谈将被选择代表肝脏研究中最重要和最及时的研究进展。将优先考虑初级、少数民族和妇女调查员。该计划还提供了两个海报会议，一对一的对话和几个额外的机会，非正式的，但亲密的科学交流之间的发言者和与会者在整个逗留。具体的会议主题包括肝脏分化和器官形成，健康和疾病中肝胆基因表达的调节，肝脏生长和再生，健康和疾病中的肝脏代谢，肝损伤和肝纤维化，遗传异常引起的肝病，肝癌，肝干细胞和再生医学和发展的影响，肝细胞移植和肝组织工程以及基础和转化肝脏病理学的最新进展。重点是最近和当前发现的翻译应用。因此，该计划整合了肝脏健康和疾病的基础和应用方面最相关和最及时的主题，以促进科学交流，传播，教育和合作以及转化为患者护理。