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Peer Approaches to Lupus Self-Management (PALS)

狼疮自我管理的同伴方法 (PALS)

基本信息

批准号：
9794139
负责人：
Edith Marie Williams
金额：
$ 50.57万
依托单位：
MEDICAL UNIVERSITY OF SOUTH CAROLINA
依托单位国家：
美国
项目类别：
财政年份：
2018
资助国家：
美国
起止时间：
2018-09-26 至 2023-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9794139
关键词：
Address Affect African American Age Arthritis Caring Caucasians Chronic Chronic Disease Clinical Control Groups Data Diabetes Mellitus Disease Disease Outcome Goals HIV Health Health Care Costs Health education Intervention Kidney Diseases Laboratories Lead Lupus Measures Mediator of activation protein Mental Depression Mentors Mentorship Minority Modeling Morbidity - disease rate Outcome Patients Physicians Prevalence Psychological reinforcement Public Health Quality of life Quality-Adjusted Life Years Questionnaires Randomized Reporting Risk Role Self Management Social support Support Groups Systemic Lupus Erythematosus Testing Time Trust United States Woman Work chronic autoimmune disease community setting cost effective cost effectiveness design disability disparity reduction effective intervention evidence base experience health related quality of life high risk population improved improved functioning improved outcome indexing innovation mortality pain reduction peer peer coaching programs study population success

项目摘要

PROJECT SUMMARY/ABSTRACT The goal of the proposed project is to test an innovative, manualized peer mentorship program for African American women with systemic lupus erythematosus (SLE). The Peer Approaches to Lupus Self- management (PALS) study is designed to provide modeling and reinforcement by peers (mentors) to other African American women with SLE (mentees) to encourage them to engage in activities that promote disease self-management. This study builds on three decades of work conducted in the field of arthritis self- management but differs in that the intervention mode (peer mentoring), the disease (SLE), and the study population (African Americans) are unstudied or understudied. Through a randomized, controlled design, we will assess the efficacy and mechanism(s) of this intervention on self-management and health related quality of life (HRQOL). This program has three specific aims. The first aim seeks to determine the efficacy of a peer mentorship intervention in African American women with SLE on disease self-management and HRQOL. The second aim is to determine the impact of a peer mentorship intervention on patient-reported and clinical indicators of disease activity. The third aim is to determine the cost effectiveness of a peer mentorship intervention on disease self-management, disease activity, and HRQOL, in African American women with SLE. An exploratory aim will be to determine the role of mediators and moderators of a peer mentorship intervention on disease activity and HRQOL outcomes in African American women with SLE, to include disease self- management, depression, trust, and social support. The immediate goal of proposed work is to determine the efficacy of the program in a randomized design. The long-term goal is to disseminate this potentially cost- effective intervention in diverse clinical and community settings in an effort to improve disease outcomes in African American women with SLE and reduce morbidity and mortality in this high risk group. This effort could result in a model for other programs that aim to improve disease self-management, disease activity, and HRQOL in African American women suffering from chronic illness.

项目总结/摘要拟议项目的目标是测试一个创新的，手工化的非洲同侪导师计划，美国女性系统性红斑狼疮（SLE）。狼疮自我的同伴方法- 管理（帕尔斯）研究旨在通过同行（导师）向其他患有SLE的非裔美国妇女（学员），鼓励她们参与促进疾病的活动自我管理这项研究建立在关节炎自我治疗领域三十年的工作基础上，管理，但不同之处在于干预模式（同伴指导），疾病（SLE）和研究非裔美国人（African Americans）是未被研究或研究不足的。通过随机对照设计，我们将评估这种干预措施对自我管理和健康相关质量的效果和机制，生活质量（HRQOL）。该方案有三个具体目标。第一个目标是确定一个同伴的效能非裔美国女性SLE患者疾病自我管理和HRQOL的指导干预。的第二个目的是确定同伴指导干预对患者报告和临床的影响。疾病活动的指标。第三个目标是确定同伴指导的成本效益对非裔美国SLE妇女疾病自我管理、疾病活动和HRQOL干预一个探索性的目标将是确定调解人和主持人的作用，同侪辅导干预非裔美国女性SLE患者的疾病活动性和HRQOL结局，包括疾病自身管理、抑郁、信任和社会支持。拟议工作的近期目标是确定在一个随机设计的程序的有效性。长期目标是传播这种潜在的成本- 在不同的临床和社区环境中进行有效干预，以改善疾病结局，非裔美国女性SLE和降低发病率和死亡率，在这个高风险群体。这项工作可以为其他旨在改善疾病自我管理、疾病活动和患有慢性疾病的非裔美国妇女的HRQOL。