Medical Marijuana, Emerging Adults, and Community: Connecting Health and Policy

项目总结/摘要 越来越多的人法律的获得大麻用于医疗和/或娱乐用途， 考虑到对公众的潜在影响，这可以说是过去20年来毒品政策最深刻的变化。 健康加州是自1996年以来批准大麻用于医疗用途的28个州之一，成为第八个州 医用大麻国家合法化大麻娱乐用途后，成人使用的通过， 2016年《海事法》（AUMA）。没有研究研究过从医疗到医疗的实时过渡。 娱乐环境及其对年轻成人大麻使用者的影响，因为国家开始合法化 2012年用于娱乐的大麻此外，没有研究探讨合法化对 18至20奥尔兹的娱乐用途-符合医疗用途但禁止娱乐用途的群体 在所有法律的州。我们对当前R 01进行更新的长期目标是为公共政策提供调查结果 在大麻法律的环境中， 用于娱乐用途。我们的目标是确定合法化对青少年大麻的影响 使用者（18至30奥尔兹）通过继续研究一组年轻人- 210医用大麻 2014-15年在加利福尼亚州洛杉矶招募了156名非患者大麻使用者（NPU）， 还招募了150名18至20岁的大麻使用者。我们的核心假设是， 将大麻合法化用于娱乐用途将导致大麻使用增加，其他药物使用和风险增加 年轻人的行为，但这种增加将因患者状态（MMP与NPU）和取向而异 大麻的使用，即，药用vs.娱乐我们提出这项研究的理由是， 更新当前的R 01将提供独特的机会：分析大麻使用，其他药物使用和风险 一组年轻的成年大麻使用者的行为， 在加州合法化;并招募一个新的未成年大麻使用者群体进行比较。 在当前R 01的初步数据的指导下，将通过以下三个方面来检验中心假设： 具体目标：1）确定大麻合法化对大麻使用轨迹的影响，包括 高效形式，例如，在MMP和NPU（21至30岁）中， 大麻合法化对其他药物使用模式和医疗和娱乐之间的风险行为 使用者（21至30岁）;和3）确定大麻合法化对态度和模式的影响， 在新招募的未成年年轻人（18至20岁）中使用大麻。该方法是 创新，因为它使用中断的时间序列设计来研究大麻合法化对 年轻成人，包括法律的和非法律的娱乐使用者，包括 在完全法律的背景下在娱乐用户中使用大麻。这项研究意义重大，因为 年轻人娱乐用大麻合法化对公共卫生的影响尚不清楚。

PROJECT SUMMARY/ABSTRACT The rising number of individuals with legal access to marijuana for medical and/or recreational use is arguably the most profound change in drug policy in the past 20 years given the potential impact on public health. California, one of 28 states that authorized marijuana for medical use since 1996, became the eighth medical marijuana state to legalize marijuana for recreational use following the passage of the Adult Use of Marijuana Act (AUMA) in 2016. No research has studied the real-time transition from a medical to a recreational environment and its impact on young adult marijuana users since states began legalizing marijuana for recreational use in 2012. Furthermore, no study has examined the impact of legalization for recreational use on 18 to 20 year olds – a group eligible for medical use but prohibited from recreational use in all legal states. Our long-term goal in this renewal of a current R01 is to inform public policy with findings on safer and controlled use of marijuana among young adults in an environment where marijuana is legal for recreational use. Our objective here is to determine the impact of legalization on young adult marijuana users (18 to 30 year olds) by continuing the study of a cohort of young adults – 210 medical marijuana patients (MMP), 156 non-patient marijuana users (NPU) - recruited in Los Angeles, CA in 2014-15 while also enrolling a new cohort of 150 18 to 20 year old marijuana users. Our central hypothesis is that legalizing marijuana for recreational use will result in increased marijuana use, other drug use, and risk behaviors among young adults, but this increase will vary by patient status (MMP vs. NPU) and orientation towards marijuana use, i.e., medicinal vs. recreational. Our rationale for the proposed research is that renewing a current R01 will offer the unique opportunity to: analyze marijuana use, other drug use, and risk behaviors on a cohort of young adult marijuana users continuously collected both before and after legalization in California; and recruit a new underage cohort of marijuana users for comparative purposes. Guided by preliminary data from the current R01, the central hypothesis will be tested by pursuing three specific aims: 1) Determine the impact of marijuana legalization on trajectories of marijuana use, including high-potency forms, e.g., dabs, edibles, among MMP and NPU (aged 21 to 30); 2) Determine the impact of marijuana legalization on patterns of other drug use and risk behaviors among medicinal and recreational users (aged 21 to 30); and 3) Determine the impact of marijuana legalization on attitudes and patterns of marijuana use among a newly recruited cohort of underage young adults (aged 18 to 20). The approach is innovative because it uses an interrupted time series design to study the effects of legalizing marijuana on young adults, includes both legal and non-legal recreational users, and includes medicinal orientation of marijuana use among recreational users in a fully legal context. The proposed research is significant since the public health impact of legalizing marijuana for recreational use among young adults is unknown.