Accounting for measured and unmeasured heterogeneity in host populations

考虑宿主群体中可测量和不可测量的异质性

• 批准号: 8796418
• 负责人: Caroline O'Flaherty Buckee
• 金额: $ 17.26万
• 依托单位: HARVARD SCHOOL OF PUBLIC HEALTH
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8796418
• 关键词: Accounting; Antimicrobial Resistance; Cholera; Communicable Diseases; Data; Dependence; Dose; Heterogeneity; Incidence; Infection; Malaria; Measures; Methods; Modeling; Population; Population Heterogeneity; Predisposition; Prevalence; Route; Source; Treatment outcome; Vaccines; Vibrio cholerae; Viral; Virus; Work; antimicrobial; pathogen; respiratory virus; response; transmission process

Project III: Accounting for Measured and Unmeasured Heterogeneity in Host Populations proposes a variety of studies to assess the contribution of host heterogeneity to model parameter estimation for infections with different transmission routes and creates models incorporating two key sources of such heterogeneity: virus interference and dose-response relationships.

项目三：解释宿主群体中可测量和不可测量的异质性提出了各种研究来评估宿主异质性对不同传播途径感染的模型参数估计的贡献，并创建了包含这种异质性的两个关键来源的模型：病毒干扰和剂量-反应关系。