HIV- and ART-ASSOCIATED CARDIOMETABOLIC RESEARCH TRAINING IN RWANDA

卢旺达艾滋病毒和艺术相关的心脏代谢研究培训

• 批准号: 9256558
• 负责人: Eugene Mutimura
• 金额: $ 30.64万
• 依托单位: RASD RWANDA
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-04-06 至 2021-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9256558
• 关键词: African; Biochemistry; Biometry; Blood Vessels; Cardiac; Cardiovascular system; Caring; Communities; Comorbidity; Custom; Data Set; Diabetes Mellitus; Education; Educational workshop; Endocrinology; Epidemiology; Faculty; Fellowship; Funding; Future; Goals; Grant; HIV; Health; Health Sciences; Investigation; Kinetics; Laboratories; Laboratory Research; Leadership; Master' s Degree; Measures; Medicine; Mentors; Mentorship; Metabolic; Methodology; Obesity; Postdoctoral Fellow; Public Health; Publications; Publishing; Research; Research Infrastructure; Research Personnel; Research Project Grants; Research Training; Rwanda; Scientist; Sustainable Development; Tracer; Training; Universities; Washington; Writing; career; career development; clinical investigation; college; design; experience; flexibility; global health; improved; medical schools; meetings; novel; nursing technique; nutrition; programs; skills; stable isotope

 DESCRIPTION (provided by applicant): The overall goal of this training strategy is to develop scientific leadership in HIV- and ART-associated cardiometabolic (CM) research in Rwanda through developing a dynamic team of scholars to implement well- designed contextually relevant studies, publish and present results at scientific meetings, and for networking, and develop expertise for independent research funding. Regional Alliance for Sustainable Development (RASD Rwanda) and University of Rwanda (UR) College of Medicine and Health Sciences (UR-CMHS) propose to collaborate with Washington University School of Medicine in St. Louis, MO, USA (WUSTL) to implement a mélange of long-, medium-, and short-term tailored didactic and hands-on training, balanced for Master's (MS) degree and non-degree face-to-face mentorships. We will provide MS in Clinical investigation training to postdoctoral scholars, followed by 3-months Mentored Career Development Fellowships, MS in Biostatistics, and MS in Biochemistry Laboratory Medicine. Research training in Endocrinology and Metabolism and advanced nursing techniques will be provided, plus technical training in stable isotope tracer methodologies for substrate kinetics measures, and echocardiographic measures of vascular and cardiac function. WUSTL Faculty assisted by previously trained mid-career Rwandan co-mentors will provide 4-weeks hands-on intensive didactic training to 15 mid-career investigators in Advanced Epidemiology & Biostatistics in Year 1, using existing Ministry of Health HIV datasets, resulting into publications. In Year 2, 4-week intensive workshop training to develop Grant Writing Skills will occur followed by post-training mentorships. Promising young and mid-career scientists will benefit from regular, custom-tailored and flexible mentoring from senior WUSTL Faculty and Rwandan co-mentors (the "mentored become mentors") to enhance the research culture at UR-CMHS, while Rwandan co-mentors will gain a breadth of skills from more experienced Faculty to train junior scientists- a pool of future mentors. We envision that 4 WUSTL Faculty will mentor 4 young scientists each, resulting in 16 successful mentorships annually, with up to 80 mentorships in 5 years. Trainees' unique HIV research projects will be supported to accelerate novel findings. Furthermore, WUSTL Summer Fellowships (8 weeks) in the Public Health Advanced Summer Education Program for Research in Global Health, and Bench Fundamentals for Translational Laboratory Research course will each accept 2 trainees/year. Upon return to Rwanda, all trainees will be integrated into the vibrant HIV research infrastructure to contribute to rigorous investigations, and to eventually enable UR to become an African scientific leader in cardiovascular and metabolic research associated with HIV, nutrition, obesity, diabetes and other related co- morbidities, with improved independent scientific capacity to attract and manage grants, and ability to inform global community on HIV care and practice.

 描述（由申请人提供）：该培训策略的总体目标是通过发展一个充满活力的学者团队，在卢旺达发展HIV和ART相关心脏代谢（CM）研究的科学领导力，以实施精心设计的背景相关研究，在科学会议上发表和展示结果，并建立网络，并为独立研究资金发展专业知识。区域可持续发展联盟（RASD卢旺达）和卢旺达大学（UR）医学与健康科学学院（UR-CMHS）提议与美国密苏里州圣路易斯的华盛顿大学医学院（WUSTL）合作，实施长期，中期和短期定制教学和实践培训，平衡硕士（MS）学位和非学位面对面指导。我们将为博士后学者提供临床研究培训MS，然后是3个月的指导职业发展奖学金，生物统计学MS和生物化学实验室医学MS。将提供内分泌学和代谢学方面的研究培训以及高级护理技术，此外还将提供用于底物动力学测量的稳定同位素示踪方法以及血管和心脏功能的超声心动图测量方面的技术培训。WUSTL教师由以前受过培训的职业中期卢旺达共同导师的协助下，将提供为期4周的动手强化教学培训，以15个职业中期调查员在先进的流行病学和生物统计学在第一年，使用现有的卫生部艾滋病毒数据集，导致出版物。在第二年，为期4周的强化研讨会培训，以发展赠款写作技能将发生培训后的辅导。有前途的年轻和中期职业科学家将受益于高级WUSTL教师和卢旺达共同导师（“指导成为导师”）的定期，定制和灵活的指导，以加强UR-CMHS的研究文化，而卢旺达共同导师将从更有经验的教师那里获得广泛的技能，以培训初级科学家-未来的导师库。我们设想，4个WUSTL教师将指导4名年轻科学家，每年有16个成功的导师，5年内有多达80个导师。将支持学员独特的艾滋病毒研究项目，以加快新的发现。此外，WUSTL夏季奖学金（8周）在公共卫生高级夏季教育计划的研究在全球健康，和实验室研究的基本原理转化课程将每年接受2名学员。返回卢旺达后，所有受训人员将被纳入充满活力的艾滋病毒研究基础设施，为严格的调查作出贡献，并最终使乌拉圭成为非洲与艾滋病毒、营养、肥胖、糖尿病和其他相关并发症有关的心血管和代谢研究的科学领导者，提高吸引和管理赠款的独立科学能力，以及向全球社会通报艾滋病毒护理和实践的能力。