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中文摘要
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职业发展计划(CDP)是杜克大学孢子课程的关键组成部分 有助于识别、支持和指导有希望的新的和早期的脑癌 翻译神经肿瘤学的研究人员。将鼓励项目广泛协作,并 测试新的范例,将进一步扩大脑肿瘤的诊断、预防和治疗的范围 管理层。DRP将专门针对有很大可能性成功的项目,并 独立研究项目或具有很高发展潜力的全孢子项目 孢子内进展不令人满意的项目。CDP的具体目标是: 1)确定并支持由NIH牵头的有价值的翻译项目-指定的新阶段或早期阶段 极有可能影响诊断、治疗或预防的调查人员 脑肿瘤; 2)招聘和留住有前途的妇女和少数族裔新的和早期的调查员 转化性神经肿瘤学研究的职业重点; 3)促进获得领导力培训计划和非常成功的赠款计划 写作,包括对早期和新的调查人员进行指导,以使这些教员能够 成员取得独立教员地位,重点是神经肿瘤学研究;以及 4)持续评价受资助项目的进展情况,并促进其演变为 全孢子项目或独立资助项目。 这个应用程序建立在之前杜克大学脑癌孢子非常成功的CDP基础上 导致了几位早期科学家的成功发展,包括一些妇女和 少数族裔调查员。此应用程序通过集成 孢子CDP拥有非常先进的教师发展计划,提供广泛的短期课程 使年轻教员能够学习与领导力、科学写作、人事管理、补助金有关的技能 管理层和其他人。CDP与学院发展办公室的这种整合将确保 CDP奖获得者在我们医疗机构任职期间的纵向指导和发展 中间。我们期待着在神经肿瘤学领域成功招聘优秀的新人才。 研究,就像我们过去所做的那样,通过这个高知名度的奖项计划。
英文摘要
The Career Development Program (CDP) is a critical and integral component of the Duke SPORE in Brain Cancer that facilitates the identification, support, and mentoring of promising new and early-stage investigators in translational neuro-oncology. Projects will be encouraged to be broadly collaborative and to test novel paradigms that will further expand the scope of the brain tumor diagnosis, prevention, and management. The DRP will specifically target projects having a strong likelihood of becoming successful and independent research projects or having a high potential of developing into full SPORE projects that replace projects within the SPORE that are not progressing satisfactorily. The Specific Aims of the CDP are to: 1) Identify and support meritorious translational projects led by NIH-designated new or early stage investigators that have a high probability of impacting the diagnosis, treatment or prevention of brain tumors; 2) Recruit and retain promising women and minority new and early-stage investigators with a career focus in translational neuro-oncology research; 3) Facilitate access to programs for leadership training and a highly successful program for grant writing that includes mentoring of early-stage and new investigators to enable such faculty members to achieve independent faculty status with emphasis on neuro-oncology research; and 4) Provide continuing evaluation of progress on funded projects and facilitate their evolution into full SPORE projects or independently funded projects. This application builds upon the highly successful CDP of the previous Duke Brain Cancer SPORE that resulted in the successful development of several early-stage scientists, including a number of women and minority investigators. This application builds upon and extends this success through the integration of the SPORE CDP with a highly advanced faculty development program, which offers a wide range of short courses to enable young faculty to learn skills related to leadership, scientific writing, personnel management, grants management and others. This integration of the CDP with the Office of Faculty Development will ensure longitudinal mentorship and development of CDP award recipients throughout their tenure at our medical center. We anticipate the successful recruitment of outstanding new talent to the field of neuro-oncology research, as we have done in the past, through this highly visible awards program.
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ATRX mutations, innate immune activation and therapeutic vulnerability in malignant gliomas
  • 批准号:
    10375084
  • 项目类别:
  • 资助金额:
    $42.23万
  • 财政年份:
    2022
  • 负责人:
    David M. Ashley
  • 依托单位:
ATRX mutations, innate immune activation and therapeutic vulnerability in malignant gliomas
  • 批准号:
    10666347
  • 项目类别:
  • 资助金额:
    $37.7万
  • 财政年份:
    2022
  • 负责人:
    David M. Ashley
  • 依托单位:
Administrative Core
  • 批准号:
    10488238
  • 项目类别:
  • 资助金额:
    $12.35万
  • 财政年份:
    2021
  • 负责人:
    David M. Ashley
  • 依托单位:
6-thio-2'-deoxyguanosine in GBM: Pre-clinical Evaluation of Mechanism of action, Efficacy and Biomarker identification
  • 批准号:
    10488242
  • 项目类别:
  • 资助金额:
    $52.22万
  • 财政年份:
    2021
  • 负责人:
    David M. Ashley
  • 依托单位:
海外基金