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中文摘要
翻译
职业发展计划(CDP)是杜克SPORE的重要组成部分, 脑癌,有利于识别,支持和指导有前途的新的和早期阶段 转化神经肿瘤学的研究者。将鼓励项目广泛合作, 测试新的范例,将进一步扩大脑肿瘤诊断,预防和治疗的范围。 管理DRP将专门针对有很大成功可能性的项目, 独立的研究项目或具有发展成为完整的SPORE项目的高潜力, 在项目中,没有取得令人满意的进展。发展政策委员会的具体目标是: 1)识别和支持由NIH指定的新的或早期阶段领导的有价值的翻译项目 有很大可能影响诊断、治疗或预防的研究者 脑肿瘤; 2)招聘和留住有前途的妇女和少数民族新的和早期的调查人员, 专注于转化神经肿瘤学研究; 3)促进获得领导力培训计划和一个非常成功的赠款计划 写作,包括指导早期阶段和新的调查人员,使这样的教师 成员实现独立的教师地位,重点是神经肿瘤学研究; 4)持续评估资助项目的进展情况,并促进其发展成为 完全的SPORE项目或独立资助的项目。 该应用程序建立在之前杜克脑癌孢子的高度成功的CDP基础上, 成功培养了几位早期科学家,其中包括一些女性, 少数民族调查员此应用程序构建在此成功的基础上,并通过集成 SPORE CDP拥有高度先进的教师发展计划,提供广泛的短期课程 使年轻的教师能够学习与领导力,科学写作,人事管理,赠款 管理及其他。CDP与教师发展办公室的整合将确保 CDP奖获得者在我们的医疗机构任职期间的纵向指导和发展 中心我们期待在神经肿瘤学领域成功招募优秀的新人才 研究,就像我们过去所做的那样,通过这个高度可见的奖项计划。
英文摘要
The Career Development Program (CDP) is a critical and integral component of the Duke SPORE in Brain Cancer that facilitates the identification, support, and mentoring of promising new and early-stage investigators in translational neuro-oncology. Projects will be encouraged to be broadly collaborative and to test novel paradigms that will further expand the scope of the brain tumor diagnosis, prevention, and management. The DRP will specifically target projects having a strong likelihood of becoming successful and independent research projects or having a high potential of developing into full SPORE projects that replace projects within the SPORE that are not progressing satisfactorily. The Specific Aims of the CDP are to: 1) Identify and support meritorious translational projects led by NIH-designated new or early stage investigators that have a high probability of impacting the diagnosis, treatment or prevention of brain tumors; 2) Recruit and retain promising women and minority new and early-stage investigators with a career focus in translational neuro-oncology research; 3) Facilitate access to programs for leadership training and a highly successful program for grant writing that includes mentoring of early-stage and new investigators to enable such faculty members to achieve independent faculty status with emphasis on neuro-oncology research; and 4) Provide continuing evaluation of progress on funded projects and facilitate their evolution into full SPORE projects or independently funded projects. This application builds upon the highly successful CDP of the previous Duke Brain Cancer SPORE that resulted in the successful development of several early-stage scientists, including a number of women and minority investigators. This application builds upon and extends this success through the integration of the SPORE CDP with a highly advanced faculty development program, which offers a wide range of short courses to enable young faculty to learn skills related to leadership, scientific writing, personnel management, grants management and others. This integration of the CDP with the Office of Faculty Development will ensure longitudinal mentorship and development of CDP award recipients throughout their tenure at our medical center. We anticipate the successful recruitment of outstanding new talent to the field of neuro-oncology research, as we have done in the past, through this highly visible awards program.
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ATRX mutations, innate immune activation and therapeutic vulnerability in malignant gliomas
  • 批准号:
    10375084
  • 项目类别:
  • 资助金额:
    $42.23万
  • 财政年份:
    2022
  • 负责人:
    David M. Ashley
  • 依托单位:
ATRX mutations, innate immune activation and therapeutic vulnerability in malignant gliomas
  • 批准号:
    10666347
  • 项目类别:
  • 资助金额:
    $37.7万
  • 财政年份:
    2022
  • 负责人:
    David M. Ashley
  • 依托单位:
Administrative Core
  • 批准号:
    10488238
  • 项目类别:
  • 资助金额:
    $12.35万
  • 财政年份:
    2021
  • 负责人:
    David M. Ashley
  • 依托单位:
6-thio-2'-deoxyguanosine in GBM: Pre-clinical Evaluation of Mechanism of action, Efficacy and Biomarker identification
  • 批准号:
    10488242
  • 项目类别:
  • 资助金额:
    $52.22万
  • 财政年份:
    2021
  • 负责人:
    David M. Ashley
  • 依托单位:
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