Pittsburgh Intensive Training in Hematology Research

匹兹堡血液学研究强化培训

• 批准号: 9494640
• 负责人: Gregory J Kato
• 金额: $ 7.65万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-08-15 至 2020-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9494640
• 关键词: Advisory Committees; Affect; Africa; Applications Grants; Area; Basic Science; Biology; Birth; Blood; Blood Vessels; Center for Translational Science Activities; Cessation of life; Child; Clinical; Clinical Research; Clinical Sciences; Coagulation Process; Competence; Country; Coupled; Diagnosis; Discipline; Disease; Doctor of Philosophy; Dyspnea; Education Projects; Environment; Faculty; Fellowship; Ghana; Goals; Hematological Disease; Hematology; Hematopoietic stem cells; Heme Iron; Hemoglobin; Hemolysis; Hemostatic Agents; Hospitalization; Human; Immersion Investigative Technique; Income; Individual; Institution; Internships; Laboratories; Learning; Malaria; Medicine; Mendelian disorder; Mentors; Methodology; Molecular Biology; Morbidity - disease rate; Mus; Patients; Pharmacology; Phenotype; Population Growth; Postdoctoral Fellow; Process; Pulmonary Hypertension; Regenerative Medicine; Research; Research Personnel; Research Project Grants; Research Training; Resources; Risk; Science; Scientist; Sickle Cell; Sickle Cell Anemia; Signal Transduction; Tanzania; Techniques; Thalassemia; Therapeutic; Thrombosis; Time; Training; Training Programs; Training and Education; Transfusion; Translational Research; United States; United States National Institutes of Health; Universities; Vascular Diseases; beta Thalassemia; burden of illness; career; career development; cohort; experience; graduate student; induced pluripotent stem cell; innovative technologies; interest; iron metabolism; lectures; man; medical specialties; member; mortality; novel therapeutic intervention; oncology; patient oriented; patient population; programs; skill acquisition; trend

 DESCRIPTION (provided by applicant): The goal of this application is to enrich the hematology research workforce through the provision of a six-month educational and training experience in innovative technologies and conceptual paradigms related to blood science, in particular hemolysis-related vascular biology, at the University of Pittsburgh. The focus of the Pittsburgh Intensive Training in Hematology Research Program is training in experimental and translational hematology for graduate students, postdoctoral scientists, and junior faculty investigators. Its objective is to enhance skills development at key stages of the training of bloo scientists through a mentored didactic and hands-on practical course in experimental and translational hematology coupled with a pilot research project. It is intended primarily for graduate students pursuing PhD degrees who need to learn a specialized hematologic technique, early-stage postdocs interested in blood science who need an intensive course to catalyze a career switch to hematological research, and junior faculty investigators with a strong interest in developing a career in basic and translational sickle cell disease research. A total of 23 University of Pittsburgh academic core faculty from the broad disciplines of hematology/oncology, vascular biology, molecular biology, pharmacology, coagulation and thrombosis, transfusion medicine, and regenerative medicine at the University of Pittsburgh are available to provide a broad array of basic and translational research topics and study patient populations to carry out this project. The program is focused on multiple areas of hematology research including hemolysis-related vascular disorders, sickle cell disease, heme and iron metabolism and signaling, hematopoietic stem cell and iPS. Training will incorporate the learning of cutting edge hematologic methodologies that is applied to a clinical problem, leading to potentially novel therapeutic approaches or clinical studies in patients. Trainees will choose from a variety of advanced research hematology techniques and will have the option to pursue internship in thrombosis, and a patient-oriented sickle cell internship in Africa working on large patient cohorts. (End of Abstract)

 描述(申请人提供)：该申请的目标是通过在匹兹堡大学提供为期六个月的与血液科学相关的创新技术和概念范例的教育和培训经验，特别是与溶血相关的血管生物学，来丰富血液学研究队伍。匹兹堡血液学研究强化培训计划的重点是为研究生、博士后科学家和初级教职调查人员提供实验和翻译血液学方面的培训。它的目标是通过实验和翻译血液学的指导性和动手实践课程以及一个试点研究项目，在BLOO科学家培训的关键阶段加强技能发展。它主要面向需要学习专门血液学技术的攻读博士学位的研究生，对血液科学感兴趣的早期博士后，他们需要强化课程来催化职业生涯向血液学研究的转变，以及对发展基础和转化性镰状细胞疾病研究事业有浓厚兴趣的初级教研员。总计 23匹兹堡大学学术核心教员来自匹兹堡大学血液学/肿瘤学、血管生物学、分子生物学、药理学、凝血和血栓形成、输血医学和再生医学等广泛学科，可提供广泛的基础和转化性研究课题，并研究患者群体，以实施这一项目。该计划专注于多个血液学研究领域，包括溶血相关的血管疾病、镰状细胞疾病、血红素和铁代谢与信号、造血干细胞和iPS。培训将结合应用于临床问题的尖端血液学方法的学习，导致潜在的新的治疗方法或患者的临床研究。受训人员将从各种先进的血液学研究技术中进行选择，并可以选择在血栓形成方面进行实习，以及在非洲进行以患者为导向的镰状细胞实习，在大的患者队列中工作。(摘要结束)