The PDX Integrator- Re-purposing KOMP2 informatics to widely disseminate data from Patient Derived Xenografts
PDX Integrator - 重新利用 KOMP2 信息学来广泛传播来自患者来源的异种移植物的数据
基本信息
- 批准号:9260869
- 负责人:
- 金额:$ 38.35万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2016
- 资助国家:美国
- 起止时间:2016-04-15 至 2021-03-31
- 项目状态:已结题
- 来源:
- 关键词:American Association of Cancer ResearchArchivesAtlasesAutomobile DrivingBiologicalBiological AssayCancer BiologyCancer ModelCancer PatientCommon Data ElementCommunitiesCommunity OutreachComplexComputer softwareDataData SetData SourcesDatabasesDevelopmentDisease ProgressionEducational workshopEnd Point AssayEngraftmentEnvironmentFeedbackFundingGene ExpressionGrantGraphHumanImageImageryImmunocompromised HostInformaticsInternationalIntuitionKnockout MiceKnowledgeLearningLibrariesLinkLocationMapsMeasuresMetadataModelingMolecular Classification of TumorsMouse StrainsMusMutant Strains MiceMutationNCI ThesaurusOncogenicPatientsPharmaceutical PreparationsPharmacotherapyPhysiologicalProceduresPublicationsResearchResearch InfrastructureResearch PersonnelResourcesScientistSecureSiteStandardizationTestingTherapeuticTo specifyTrainingTransplantationTumor BiologyWorkXenograft ModelXenograft procedureanticancer researchdata acquisitiondata modelingdata resourcedata visualizationexperiencegenomic dataimplantationinformatics infrastructuremeetingsmouse modelneoplasm resourceoncologyphenomepreventprototypepublic health relevancerepositoryresponsesocial mediasoftware developmentsuccesstooltreatment responsetumortumor growthtumor progressionuser-friendly
项目摘要
DESCRIPTION (provided by applicant): Patient Derived Xenografts are a critical and growing resource for cancer biology. They inform the understanding of cancer progression, treatment and represent a valuable and under integrated resource. These data consist of complex Meta data related to the tumor and its progression in mouse model. Omics, drug, assay and image data provide rich characterization of PDXs and offer integration potential with existing tools, dat archives and analysis platforms. The PDX Integrator will build on existing infrastructure developed for the Knockout Mouse Project 2 and has four tasks: 1) Identify key determinants in PDX models, map to existing data standards and work with the community to define, extend and where necessary modify existing standards 2) Extend the existing KOMP2 data acquisition software to acquire, validate and load PDX associated data 3) Deploy the PDX Integrator to provide user friendly overviews of PDX data including biological image data and graphical visualization of end-point data by adapting the KOMP2 resource data visualization and presentation tools. 4) Targeted community outreach during all stages of the project to determine and prioritize requirements, guide development and promote the PDX Integrator.
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Helen Elizabeth Parkinson的其他文献
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{{ truncateString('Helen Elizabeth Parkinson', 18)}}的其他基金
Patient Derived Cancer Model (PDCM) Finder
患者衍生癌症模型 (PDCM) 查找器
- 批准号:
10260591 - 财政年份:2020
- 资助金额:
$ 38.35万 - 项目类别:
Patient Derived Cancer Model (PDCM) Finder
患者衍生癌症模型 (PDCM) 查找器
- 批准号:
10058856 - 财政年份:2020
- 资助金额:
$ 38.35万 - 项目类别:
Patient Derived Cancer Model (PDCM) Finder
患者衍生癌症模型 (PDCM) 查找器
- 批准号:
10456865 - 财政年份:2020
- 资助金额:
$ 38.35万 - 项目类别:
Patient Derived Cancer Model (PDCM) Finder
患者衍生癌症模型 (PDCM) 查找器
- 批准号:
10672210 - 财政年份:2020
- 资助金额:
$ 38.35万 - 项目类别:
The PDX Integrator- Re-purposing KOMP2 informatics to widely disseminate data from Patient Derived Xenografts
PDX Integrator - 重新利用 KOMP2 信息学来广泛传播来自患者来源的异种移植物的数据
- 批准号:
9458368 - 财政年份:2016
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10218234 - 财政年份:2014
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