Establishing the GWAS Catalog as a resource for large-scale association studies

作为EMBL-EBI和EMBL-EBI之间的持续合作，已成功交付Gwas目录 NHGRI，这将继续作为下一个五年计划的一部分。菲奥娜·坎宁安加盟现有的PI海伦 帕金森和保罗·弗利切克，他们将共同完成目录开发的下一阶段。这个 目录的分发将通过图形用户界面、下载功能、API 功能、使用目录的代码库、追踪器、出版物以及 目录组。外展活动将继续服务于现有的用户社区，并旨在扩大 用户基础，通过使用社交媒体、与数据生成器的交互、通过使用社交媒体瞄准特定用户群体、 与遗传学以及通过信息学用户社区和出版商的科学会议。新的 与工具开发人员和出版商合作，使用社区批准的方式促进作者沉积 标准格式将支持资源生产和资源信息学活动，这将 实施这些工具。对目录用户的培训将通过以下网站上的在线培训课程提供 EMBL-EBI的列车在线平台。还将应要求提供社区研讨会和研讨会 申请将与EnSembl一起提交给主要会议，以最大限度地提高 访问用户。“培训培训者”模型将用于确定将作为培训者的个人 目录，我们将向他们免费提供所有培训材料和目录流程。Embl-EBI‘s 行业计划和开放目标合作将被利用来获取国际制药 以确保培训具有最大可能的覆盖面。该目录的科学顾问委员会 (SAB)将代表用户社区，并为PIS和EMBL-EBI/NHGRI协作者提供论坛 以富有成效和投入的方式讨论进展。SAB将在ASHG之前每年召开一次会议 会议，并将就全球气候变化领域的新兴技术和挑战提供建议，以支持 该目录包括关于复杂疾病的最新发现和研究使用的基本知识 和药物开发社区，以造福人类健康。国安局也将在 Catalog的社区参与战略。

The GWAS Catalog has been successfully delivered as an ongoing collaboration between EMBL-EBI and NHGRI, which will continue as part of the next five-year plan. Fiona Cunningham joins existing PIs Helen Parkinson and Paul Flicek and together they will deliver the next phase of the Catalog’s development. The Catalog’s dissemination will take place via the graphical user interface, the download function, the API function, access to the Catalog’s codebase, tracker, publications and the outreach activities performed by the Catalog team. The outreach activities will continue to serve the existing user community and aim to grow the user base by targeting specific user groups via use of social media, interactions with data generators, at scientific meetings with the genetics and via the informatics user communities and publishers. New engagement with tools developers and publishers to promote author deposition using community approved standard formats will support the Resource Production and Resource Informatics activities which will implement these tools. Training for the Catalog’s users will be provided via an online training course hosted on the EMBL-EBI’s train online platform. Community workshops will also be offered on request and workshop applications will be submitted to major conferences in conjunction with Ensembl to maximise the ability to access users. The ‘train the trainer’ model will be used to identify individuals who will act as trainers for the Catalog and we will make all training materials and Catalog processes freely available to them. EMBL-EBI’s Industry Program and Open Targets Collaboration will be leveraged to access international pharmaceutical users to ensure that the training has the greatest possible reach. The Catalog‘s Scientific Advisory Board (SAB) will represent the user community and provide a forum for the PIs and EMBL-EBI/NHGRI collaborators to discuss progress in a productive and invested manner. The SAB will meet yearly, prior to the ASHG meeting, and will provide advice on emerging technologies and challenges in the GWAS domain, to support the Catalog in including the latest findings on complex diseases and fundamental knowledge used by research and drug development communities for the benefit of human health. The SAB will also play a role in the Catalog’s community engagement strategy.