Establishing the GWAS Catalog as a resource for large-scale association studies

作为EMBL-EBI与 NHGRI，将作为下一个五年计划的一部分继续实施。菲奥娜坎宁安加入现有的PI海伦 Parkinson和Paul Flicek，他们将共同完成目录开发的下一阶段。的 目录的传播将通过图形用户界面、下载功能、API 功能，访问目录的代码库，跟踪器，出版物和由 目录团队。外联活动将继续服务于现有的用户群体，并旨在扩大 通过使用社交媒体、与数据生成器的交互、 与遗传学的科学会议，并通过信息学用户社区和出版商。新 与工具开发商和出版商合作，使用社区批准的工具促进作者沉积 标准格式将支持资源生产和资源信息学活动， 使用这些工具。目录用户的培训将通过网上培训课程提供， EMBL-EBI的培训在线平台。还将根据要求提供社区讲习班， 申请将提交给与Ensembl合作的主要会议，以最大限度地提高 访问用户。“培训培训员”模式将用于确定将担任培训员的个人， 我们将免费向他们提供所有培训材料和目录流程。EMBL-EBI 行业计划和开放目标合作将被利用，以获得国际制药 用户，以确保培训具有最大的可能范围。目录科学顾问委员会 (SAB)将代表用户社区，并为PI和EMBL-EBI/NHGRI合作者提供论坛 以富有成效和投入的方式讨论进展情况。SAB将在ASHG之前每年举行一次会议 会议，并将提供有关GWAS领域新兴技术和挑战的建议，以支持 该目录包括复杂疾病的最新发现和研究所用的基本知识 和药物开发社区，以造福人类健康。SAB还将在以下方面发挥作用： Catalog的社区参与战略。

The GWAS Catalog has been successfully delivered as an ongoing collaboration between EMBL-EBI and NHGRI, which will continue as part of the next five-year plan. Fiona Cunningham joins existing PIs Helen Parkinson and Paul Flicek and together they will deliver the next phase of the Catalog’s development. The Catalog’s dissemination will take place via the graphical user interface, the download function, the API function, access to the Catalog’s codebase, tracker, publications and the outreach activities performed by the Catalog team. The outreach activities will continue to serve the existing user community and aim to grow the user base by targeting specific user groups via use of social media, interactions with data generators, at scientific meetings with the genetics and via the informatics user communities and publishers. New engagement with tools developers and publishers to promote author deposition using community approved standard formats will support the Resource Production and Resource Informatics activities which will implement these tools. Training for the Catalog’s users will be provided via an online training course hosted on the EMBL-EBI’s train online platform. Community workshops will also be offered on request and workshop applications will be submitted to major conferences in conjunction with Ensembl to maximise the ability to access users. The ‘train the trainer’ model will be used to identify individuals who will act as trainers for the Catalog and we will make all training materials and Catalog processes freely available to them. EMBL-EBI’s Industry Program and Open Targets Collaboration will be leveraged to access international pharmaceutical users to ensure that the training has the greatest possible reach. The Catalog‘s Scientific Advisory Board (SAB) will represent the user community and provide a forum for the PIs and EMBL-EBI/NHGRI collaborators to discuss progress in a productive and invested manner. The SAB will meet yearly, prior to the ASHG meeting, and will provide advice on emerging technologies and challenges in the GWAS domain, to support the Catalog in including the latest findings on complex diseases and fundamental knowledge used by research and drug development communities for the benefit of human health. The SAB will also play a role in the Catalog’s community engagement strategy.