Integrative Training in Oncogenic Signaling

致癌信号综合培训

• 批准号: 9312769
• 负责人: Philip H Howe
• 金额: $ 31.8万
• 依托单位: MEDICAL UNIVERSITY OF SOUTH CAROLINA
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-07-08 至 2021-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9312769
• 关键词: Oncogenic; Signal Transduction; Training

PROJECT SUMMARY/ABSTRACT This proposal seeks National Cancer Institute (NCI) support for an exciting new Integrative Training in Oncogenic Signaling (ITOS) Program that has been developed by a select group of cancer scientists affiliated with the Hollings Cancer Center (HCC) at the Medical University of South Carolina (MUSC). The ITOS Program takes place in this active and growing medical center environment with state-of-the-art facilities, a vibrant NCI-designated cancer center, and an active Office of Postdoctoral Affairs. Led by a Program Director with an exceptionally strong cancer research background and leadership experience, the ITOS Program will select and support the placement of trainees in experienced, well-funded, productive laboratories led by the Program Faculty who reside in an interactive, multi-departmental research environment with extensive resources. Each trainee will have a primary mentor and one or two secondary mentors with complementary expertise to ensure distinct and valuable perspectives that will enhance the overall cancer-related research training experience. The objectives of this training program are to provide proactive mentoring and oversight and research training in cutting-edge methodology; to develop useful academic and essential career development skills; to foster collaborative, interdisciplinary interactions with faculty and other trainees; and to provide exposure to current cancer research discoveries and how these are being translated into novel approaches to prevention, diagnosis, and treatment of cancer. Slated to train five postdoctoral trainees each year for five years, this robust training opportunity has seven programmatic components essential in obtaining the aforementioned objectives. These include the following components: 1) 33 Program Faculty who share common interests in cancer research and will provide the essential mentoring for trainees; 2) one to two year experiences in Program Faculty laboratories found within the vibrant HCC research environment; 3) an ITOS Program Research Club providing an engaging community forum for the trainees and Program Faculty to discuss work in progress as well as the latest discoveries in cancer science; 4) shared research resource workshops and tailored training with experts in cutting-edge biotechnologies; 5) interdisciplinary engagement with trainees in HCC-sponsored thematic research retreats, symposia, work in progress meetings, and seminars; 6) career development workshops and courses that will equip trainees for independent success; and 7) opportunities to network nationally at a minimum of two professional conferences each year. In summary, the ITOS Program will offer distinct experiences and opportunities only afforded to the selected ITOS Fellows, and the program, led by an outstanding cadre of Program Faculty, is anticipated to be highly attractive to emerging junior investigators locally and nationally.

项目总结/摘要 该提案寻求国家癌症研究所（NCI）支持一项令人兴奋的新的综合培训， 致癌信号（ITOS）计划，已由一组选定的癌症科学家附属 与南卡罗来纳州医科大学的霍林斯癌症中心合作。关于ITOS 计划发生在这个活跃和不断发展的医疗中心环境与国家的最先进的设施， 充满活力的NCI指定的癌症中心，以及活跃的博士后事务办公室。由项目总监领导 ITOS计划拥有非常强大的癌症研究背景和领导经验， 选择并支持将受训人员安置在由国家实验室领导的经验丰富、资金充足、富有成效的实验室， 计划教师谁居住在一个互动的，多部门的研究环境与广泛的 资源每名学员将有一名初级导师和一至两名二级导师， 专业知识，以确保独特和有价值的观点，将加强整体癌症相关的研究 培训经验。该培训计划的目标是提供积极的指导和监督 和研究前沿方法的培训;发展有用的学术和基本职业 发展技能;促进与教师和其他学员的合作，跨学科的互动;以及 提供接触目前的癌症研究发现，以及这些发现如何被转化为新的 预防、诊断和治疗癌症的方法。 计划在五年内每年培养五名博士后，这个强大的培训机会有七个 实现上述目标所必需的方案组成部分。这些包括以下内容 组成部分：1）33名在癌症研究方面有共同兴趣的计划教师，并将提供 为学员提供必要的指导; 2）在项目学院实验室工作一到两年的经验， 充满活力的HCC研究环境; 3）ITOS计划研究俱乐部提供了一个引人入胜的社区 论坛的学员和计划教师讨论正在进行的工作，以及最新的发现， 癌症科学; 4）共享研究资源研讨会，并与前沿领域的专家进行量身定制的培训 生物技术; 5）在HCC赞助的主题研究务虚会中与学员进行跨学科接触， 专题讨论会、工作进展会议和研讨会; 6）职业发展讲习班和课程， 使受训者具备独立取得成功的能力;以及7）有机会在全国范围内建立网络， 每年的专业会议。总之，ITOS计划将提供独特的经验， 机会只提供给选定的ITOS研究员，和该计划，由一个优秀的干部， 计划教师，预计将是非常有吸引力的新兴初级研究人员在当地和全国。