A Novel Mobile Health Fitness Program for AYA Childhood Cancer Survivors

针对 AYA 儿童癌症幸存者的新型移动健康健身计划

• 批准号: 9195700
• 负责人: Katie A Devine
• 金额: $ 16.49万
• 依托单位: RBHS -CANCER INSTITUTE OF NEW JERSEY
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-02-14 至 2019-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9195700
• 关键词: Accelerometer; Address; Adolescent; Adolescent and Young Adult; Advisory Committees; Area; Award; Behavior; Behavior Therapy; Behavioral Sciences; Biological; Cancer Control; Cancer Survivorship; Cardiovascular Diseases; Cardiovascular system; Cellular Phone; Cessation of life; Chronic; Clinical; Complement; Control Groups; Data; Development; Development Plans; Doctor of Philosophy; Effectiveness; Enhancement Technology; Exercise; Exercise Physiology; Fatigue; Feedback; Generic Drugs; Goals; Growth; Hand; Health; Health Technology; Instruction; Internet; Intervention; K-Series Research Career Programs; Late Effects; Life Style; Malignant Childhood Neoplasm; Malignant Neoplasms; Measures; Mentors; Methods; Mission; Monitor; Motivation; Obesity; Participant; Patient Care; Patient Self-Report; Physical Fitness; Physical activity; Population; Premature Mortality; Public Health; Publishing; Quality of life; Randomized; Randomized Clinical Trials; Reporting; Research; Research Personnel; Research Project Grants; Risk; Risk Factors; Running; Science; Site; Social Network; Specificity; Survivors; Testing; Training; Validation; Waiting Lists; Walking; Work; base; behavior change; cancer care; cancer therapy; cardiorespiratory fitness; career development; childhood cancer survivor; design; efficacy trial; exercise program; experience; fitbit; fitness; fitness intervention; grasp; group intervention; health related quality of life; innovation; interest; mHealth; mobile application; mobile computing; multidisciplinary; muscle strength; novel; physical inactivity; pilot trial; post intervention; premature; primary outcome; programs; prototype; psychosocial; public health relevance; secondary outcome; social cognitive theory; social networking website; survivorship; therapy design; tool; treatment effect; usability; web site

DESCRIPTION (provided by applicant): Advances in treatment have fortunately led to a growth in the number of childhood cancer survivors in the US. Unfortunately, these survivors are at-risk for negative late effects from treatment, including cardiovascular disease and early death. Physical inactivity can exacerbate these risks. Adolescent survivors of childhood cancers in particular have reported significant declines in physical activity that persist following treatment Katie Devine Recuay, PhD, seeks this career development award to become an independent investigator in pediatric cancer survivorship, specializing in the concerns of adolescent and young adult (AYA) survivors. Her long-term goals are to promote healthy behaviors and enhance quality of life for AYA survivors of childhood cancers. Short-term goals include specialized training in: (1) the use of mobile health "mHealth" technology for implementing behavioral interventions, (2) biological and clinical aspects of AYA cancer survivorship, (3) the conduct of multi-site randomized clinical trials (RCTs) using behavioral interventions, and (4) exercise physiology and methods of assessment. Along with her mentors and advisory team, she has developed a training plan with specific activities to reach these goals through a combination of formal coursework, seminars, hands-on training in the assessment of cardiovascular and physical fitness, and a research project mentored by a multidisciplinary team of experts in cancer control, behavioral sciences, and exercise science. The proposed research project involves the creation of a cancer-specific mobile application (app) that complements a group-based weekly fitness program, and pilot testing of the effectiveness of this technology- enhanced program. The app will be developed based on input from AYA survivors and preliminary work she has done in this area. In the pilot RCT, 88 AYA survivors will be randomized to either the technology-enhanced fitness program or waitlist control. The primary outcome is objectively measured cardiovascular fitness. Secondary outcomes include muscle strength, health-related quality of life, and fatigue. We hypothesize that participants in the intervention group will demonstrate greater improvement across primary and secondary outcomes compared with the waitlist control. This project is innovative in its use of mHealth technology and the specificity of the intervention to AYA survivors of childhood cancers. The proposed career development plan will facilitate Dr. Devine's transition to an independent investigator with expertise in AYA survivorship concerns and the use of mHealth technology in behavioral interventions.

描述（由申请人提供）：幸运的是，治疗的进展导致了美国儿童癌症幸存者的数量增长。不幸的是，这些幸存者对治疗产生负面影响，包括心血管疾病和早期死亡。 身体上的不活动会加剧这些风险。尤其是儿童癌症的青春期幸存者报告说，在治疗后，凯蒂·迪维恩（Katie Devine Recuay）博士持续存在的体育活动下降了大幅下降，该博士寻求这一职业发展奖，以成为儿科癌症幸存者的独立研究者，专门研究青少年和年轻成人（AYA）幸存者的担忧。她的长期目标是促进健康的行为并提高儿童癌症幸存者的生活质量。短期目标包括：（1）使用移动健康“ MHealth”技术来实施行为干预措施，（2）AYA癌症幸存者的生物学和临床方面，（3）使用行为干预措施的多站点随机临床试验（RCT）的进行，以及（4）锻炼生理学和评估方法。与她的导师和咨询团队一起，她制定了一项培训计划，其中包含特定的活动，通过正式课程，研讨会，心血管和身体健康评估的动手培训以及由癌症控制专家的多学科团队指导的研究项目，以实现这些目标，以实现这些目标。拟议的研究项目涉及创建针对基于小组的每周健身计划的癌症特异性移动应用程序（APP），并对该技术增强计划的有效性进行了试点测试。该应用程序将根据AYA幸存者和她在该领域所做的初步工作的意见而开发。在Pilot RCT中，88位AYA幸存者将被随机分配到技术增强的健身计划或候补控制程序。主要结果是客观测量的心血管健康。次要结果包括肌肉力量，与健康相关的生活质量和疲劳。我们假设干预组的参与者将表现出与候补名单对照相比，主要和次要结果的改善。该项目在使用MHealth技术以及对童年癌症AY幸存者的干预特异性方面具有创新性。拟议的职业发展计划将促进Devine博士向具有AYA生存问题专业知识的独立调查员的过渡，并在行为干预中使用MHealth技术。