Young Men of Color Who Have Sex with Men Cohort Study
与男性发生性关系的年轻有色人种男性队列研究
基本信息
- 批准号:9317454
- 负责人:
- 金额:$ 186.94万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2015
- 资助国家:美国
- 起止时间:2015-08-15 至 2020-07-31
- 项目状态:已结题
- 来源:
- 关键词:AIDS preventionAIDS/HIV problemAddressAdherenceAffordable Care ActAfrican AmericanAgeAlcohol consumptionAlcohol or Other Drugs useAssessment toolAwarenessBehavior TherapyBiologicalCaringClinicCohort StudiesColorContinuity of Patient CareDataDevelopmentDiagnosisDiffusionDiseaseDisease ProgressionDisease-Free SurvivalDrug UtilizationDrug usageEnsureEpidemicFundingFutureGoalsHIVHIV InfectionsHIV SeropositivityHIV diagnosisHealthHuman immunodeficiency virus testIllicit DrugsIncidenceInfectionInsurance CoverageInterventionIntervention StudiesLatinoLos AngelesMeasuresMedicalMethodsModelingMonitorNational Institute of Drug AbuseParticipantPatientsPopulationPredispositionPreventionPrevention approachPrevention strategyPrimary Health CareProbabilityProphylactic treatmentQuality of lifeRandomizedRecruitment ActivityResearchResearch DesignResearch PriorityRiskSamplingServicesSexually Transmitted DiseasesSiteSpecimenSubstance abuse problemTestingTimeUnited States National Institutes of HealthViralViral Load resultVirusYouthantiretroviral therapyblack men who have sex with mencare seekingclinical practicecohortdesignexperiencehealth care availabilityhealth care service utilizationhigh riskhuman leukocyte antigen testingimprovedmembermenmen who have sex with menmicrobicidemobile computingmotivational enhancement therapypreventprevention servicepublic health relevanceresponseretention ratesexsocial mediatheoriestherapy designtransmission processtreatment adherenceuptakeyoung manyoung men who have sex with men
项目摘要
DESCRIPTION: U01 - Cohort Study with Young Men of Color who have Sex with Men In this fourth decade of the HIV epidemic, we continue to see 50,000 new infections annually in the U.S., particularly among Black/African American and Latino young men who have sex with men (YMSM of color), who now account for 60% of new infections among Black/African American MSM and 45% of new infections among Latino MSM. Black/African American YMSM remain five times more likely to be HIV seropositive, seven times more likely to have an undiagnosed HIV infection, and 45% more likely to be diagnosed with an STI than other YMSM. YMSM of color are also the least likely to seek and remain in HIV/AIDS care, and when they do seek care, they typically already have advanced HIV disease. Among youth who initiate antiretroviral therapy (ART), 54% will achieve viral suppression; unfortunately 57% will not be retained in care and less than 6% will remain virally suppressed. Changing the course of this epidemic is going to require a dramatically different approach to prevention. We are therefore proposing to conduct longitudinal research with a large and diverse cohort of 450 YMSM of color in order to prevent new HIV infections, reduce transmission, and reduce HIV/AIDS-related disparities by focusing on successful engagement in care. Building on the HIV Continuum of Care and Prevention paradigm (i.e., seek, test, treat, and retain in care) and the Syndemic Theory of Risk, we will use a mixed-methods study design to collect and analytically triangulate quantitative, qualitative, and biological measures at baseline and every six months. Participants will be recruited from public venues, HIV test sites, and HIV/AIDS clinics using randomized probability and purposeful sampling designs. All participants will be tracked to ensure a retention rate of 90% or better, which is a feasible target given our retention rates of 94% in the Healthy Young Men's (HYM) Study. The specific aims are to 1) better understand and operationally define what linkage, engagement, retention to care (both primary health and HIV/AIDS treatment) and adherence means to HIV- and HIV+ YMSM of color; 2) characterize and monitor over time YMSM of color's use of alcohol and illicit drugs; utilization of HIV testing and prevention services; incidence of HIV and STIs; insurance status and access to health care services, including primary care and HIV/AIDS treatment services; engagement in and utilization of health care and HIV/AIDS treatment services; retention in HIV/AIDS care and adherence to ART; and utilization of biomedical interventions, such as PrEP and PEP; and 3) identify barriers/facilitator of engagement along the HIV Continuum of Care and Prevention. The proposed research builds on close to two decades of NIH-funded research by our team focused on this and other high-risk youth populations.
产品说明:U 01-对与男性发生性关系的有色人种年轻男性的队列研究在艾滋病毒流行的第四个十年里,我们继续看到美国每年有5万例新感染,特别是在黑人/非洲裔美国人和拉丁裔男男性行为者(有色人种的YMSM)中,他们现在占黑人/非洲裔美国人MSM新感染的60%,占拉丁裔MSM新感染的45%。黑人/非洲裔美国青年男男性接触者艾滋病毒血清反应阳性的可能性仍然是其他青年男男性接触者的五倍,未确诊艾滋病毒感染的可能性是其他青年男男性接触者的七倍,被诊断患有性传播感染的可能性是其他青年男男性接触者的45%。有色人种的YMSM也是最不可能寻求和留在艾滋病毒/艾滋病护理,当他们寻求护理时,他们通常已经患有晚期艾滋病毒疾病。在开始抗逆转录病毒疗法(ART)的青年中,54%的人将实现病毒抑制;不幸的是,57%的人将无法继续接受治疗,只有不到6%的人将保持病毒抑制。改变这一流行病的发展趋势将需要采取截然不同的预防方法。因此,我们建议对450名YMSM有色人种进行大型和多样化的纵向研究,以预防新的艾滋病毒感染,减少传播,并通过专注于成功参与护理来减少艾滋病毒/艾滋病相关的差异。在艾滋病毒连续护理和预防模式的基础上(即,寻求,测试,治疗,并保留在照顾)和Syndemic理论的风险,我们将使用混合方法的研究设计,收集和分析三角定量,定性和生物措施在基线和每六个月。参与者将从公共场所、艾滋病毒检测点和艾滋病毒/艾滋病诊所招募,使用随机概率和有目的的抽样设计。将跟踪所有参与者,以确保留存率达到90%或更高,鉴于我们在健康青年男性(HYM)研究中的留存率为94%,这是一个可行的目标。具体目标是:1)更好地理解和操作定义什么联系,参与,保留护理(初级卫生和艾滋病毒/艾滋病治疗)和坚持手段艾滋病毒-和艾滋病毒+有色人种YMSM; 2)表征和监测随着时间的推移YMSM的颜色的酒精和非法药物的使用;利用艾滋病毒检测和预防服务;艾滋病毒和性传播感染的发病率;保险状况和获得保健服务的机会,包括初级保健和艾滋病毒/艾滋病治疗服务;参与和利用保健和艾滋病毒/艾滋病治疗服务;继续接受艾滋病毒/艾滋病护理和坚持抗逆转录病毒疗法;以及利用生物医学干预措施,如PrEP和PEP;和3)确定参与沿着艾滋病毒连续护理和预防的障碍/促进因素。这项拟议的研究建立在近20年的NIH资助的研究基础上,我们的团队专注于这一人群和其他高危青年人群。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Michele D. Kipke其他文献
Inflammation and minority stress: A moderated mediation model of childhood adversity and mental health in young men who have sex with men
炎症与少数群体压力:男男性行为青年童年逆境与心理健康的有调节的中介模型
- DOI:
10.1016/j.socscimed.2025.118119 - 发表时间:
2025-07-01 - 期刊:
- 影响因子:5.000
- 作者:
Laura H. Dosanjh;Cynthia Franklin;Yessenia Castro;Bridget Goosby;Fiona N. Conway;Frances A. Champagne;Luis A. Parra;Jeremy T. Goldbach;Michele D. Kipke - 通讯作者:
Michele D. Kipke
Reliability and construct validity of the needle sharing inventory.
针共享库存的可靠性和结构有效性。
- DOI:
10.3109/10826088909081833 - 发表时间:
1989 - 期刊:
- 影响因子:0
- 作者:
Michele D. Kipke;Ernest Drucker - 通讯作者:
Ernest Drucker
An evaluation of an AIDS risk reduction education and skills training (ARREST) program.
对降低艾滋病风险教育和技能培训 (ARREST) 计划的评估。
- DOI:
- 发表时间:
1993 - 期刊:
- 影响因子:7.6
- 作者:
Michele D. Kipke;Michele D. Kipke;C. Boyer;C. Boyer;Karen Hein - 通讯作者:
Karen Hein
Childrens Hospital Los Angeles: a model of integrated care for HIV-positive and very high-risk youth.
洛杉矶儿童医院:为艾滋病毒阳性和高危青少年提供综合护理的典范。
- DOI:
10.1016/s1054-139x(98)00054-8 - 发表时间:
1998 - 期刊:
- 影响因子:0
- 作者:
A. Schneir;Michele D. Kipke;L. Melchior;G. Huba - 通讯作者:
G. Huba
Risks and Opportunities: Synthesis of Studies on Adolescence. Forum on Adolescence.
风险与机遇:青春期研究综述。
- DOI:
10.1037//0022-3514.65.2.360 - 发表时间:
1999 - 期刊:
- 影响因子:7.6
- 作者:
Michele D. Kipke - 通讯作者:
Michele D. Kipke
Michele D. Kipke的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Michele D. Kipke', 18)}}的其他基金
Y2Prevent: Preventing Drug Use and HIV through Empowerment, Social Support and Mentorship
Y2Prevent:通过赋权、社会支持和指导预防吸毒和艾滋病毒
- 批准号:
9973159 - 财政年份:2018
- 资助金额:
$ 186.94万 - 项目类别:
Y2Prevent: Preventing Drug Use and HIV through Empowerment, Social Support and Mentorship
Y2Prevent:通过赋权、社会支持和指导预防吸毒和艾滋病毒
- 批准号:
9757740 - 财政年份:2018
- 资助金额:
$ 186.94万 - 项目类别:
Using Longitudinal Research to Engage African American and Latinx Sexual- and Gender-Minority Youth in the HIV Prevention and Care Continua and Reduce HIV/AIDS-Related Disparities
利用纵向研究让非裔美国人和拉丁裔性少数群体青年参与艾滋病毒预防和护理工作并减少与艾滋病毒/艾滋病相关的差距
- 批准号:
10200724 - 财政年份:2015
- 资助金额:
$ 186.94万 - 项目类别:
Young Men of Color Who Have Sex with Men Cohort Study
与男性发生性关系的年轻有色人种男性队列研究
- 批准号:
9126516 - 财政年份:2015
- 资助金额:
$ 186.94万 - 项目类别: