2017 Amygdala Function in Emotion, Cognition and Disease Gordon Research Conference and Gordon Research Seminar

2017年项目摘要杏仁核在情绪、认知和疾病中的功能GRC/GRS 杏仁核在情绪、认知和疾病中的作用戈登研究会议(GRC)是第六届 为期五天的会议定于2017年8月6日至11日在伊斯顿石山学院举行，每两年举行一次 马萨诸塞州，由安德鲁·霍姆斯和凯·泰担任主席。杏仁核被认为是一种中枢 大脑系统内的节点，从属于在不同精神状态下受到干扰的一系列较高级别的行为 精神错乱。因此，会议的重点反映了精神病学正在向框架研究的方向转变 神经回路功能异常的精神疾病。目标是1)促进跨领域的互动 学科(从基础发现研究到翻译研究)与理解 杏仁核在调节高级行为和精神疾病状态中的作用，特别是那些 成瘾和焦虑，2)突出重要的新工具和技术，可以应用于研究 杏仁核，希望打开新的科学问题和研究途径，以及3)指导 新一代科学家和科学家-临床医生，特别是妇女和其他代表性不足的少数群体 在一种高度支持和包容的环境中，各团体之间的合作。 会议将以神经科学先驱们的三次全体演讲为主旨会议开始。 (George Koob，BJ Casey和Joseph LeDoux)，选择将他们独特和权威的观点带到 该领域的状态。GRC之前将举行戈登研究研讨会(GRS)，这是一个独特的为期两天的会议 为研究生、博士后和其他初级科学家提供和交流新数据和 尖端的想法。 对杏仁核的兴趣，这是一种已知在情绪和奖励过程中发挥关键作用的大脑结构 近几年有相当大的增长。事实上，杏仁核的可塑性有明显的重叠。 例如，在药物滥用和焦虑的模型中，机制被发现是不适应的。除此之外，还有一个 令人信服的临床证据表明杏仁核与创伤后应激障碍有关 精神障碍、自闭症和物质使用障碍以及其他成瘾。出于这些原因，世界银行的一个主要目标是 会议的目的是进一步将成瘾领域的调查人员及其研究纳入这个GRC的框架中。 这将通过一位领先的成瘾调查员(Koob)的主题演讲来实现，并包括 通过NIDA和NIAAA的演讲明确关注成瘾和相关主题的多个会议 资助药物滥用和成瘾科学领域的领导者。我们希望这些演示文稿能够展示 研究药物滥用中的杏仁核和刺激交叉受精的创新研究方法 在成瘾研究和杏仁核其他方面的工作之间。

PROJECT SUMMARY 2017 Amygdala Function in Emotion, Cognition & Disease GRC/GRS The Amygdala Function in Emotion, Cognition & Disease Gordon Research Conference (GRC) is the sixth biennial installment of a five-day meeting scheduled for August 6-11 2017 at Stonehill College, Easton, Massachusetts, to be chaired by Andrew Holmes and Kay Tye. The amygdala has been identified as a central node within brain systems subserving an array of higher-order behaviors that are disturbed in various mental disorders. Thus, the focus of the meeting reflects an ongoing shift in psychiatry towards framing the study of mental illness in terms of aberrant neural circuit functions. The aims are 1) to foster interactions across disciplines (from basic discovery research to translational research) related to understanding the role of the amygdala in mediating higher-order behaviors and mental disease states, particularly those characterized by addiction and anxiety, 2) to highlight important new tools and techniques that may be applied to the study of the amygdala, with the hope of opening new scientific questions and avenues of research, and 3) to mentor a new generation of scientists and scientist-clinicians, particularly women and other underrepresented minority groups, in a highly supportive and inclusive setting. The meeting will open with a Keynote session consisting of three plenary lectures by pioneers in neuroscience (George Koob, BJ Casey and Joseph LeDoux), selected to bring their unique and authoritative perspectives on the state of the field. The GRC will be preceded by a Gordon Research Seminar (GRS) is a unique two-day forum for graduate students, post-docs and other junior scientists to present and exchange new data and cutting edge ideas. Interest in the amygdala, a brain structure known to play a pivotal role in emotional and reward processes, has increased considerably in recent years. Indeed, there is marked overlap in the amygdala plasticity mechanisms found to be maladaptive in models of, for example, drug abuse and anxiety. Added to this is a compelling body of clinical evidence implicating the amygdala in disorders ranging from post-traumatic stress disorder, autism and substance use disorders and other addictions. For these reasons, a central goal of the meeting is to further integrate investigators in the addiction field, and their research, into the fabric of this GRC. This will be achieved via a keynote lecture from a leading addiction investigator (Koob) and the inclusion of multiple sessions that explicitly focus on addiction and related themes through talks from NIDA and NIAAA funded leaders in the science of drug abuse and addiction. We expect these presentations to showcase innovative research approaches to studying the amygdala in drug abuse, and to stimulate cross-fertilization between addiction research and other aspects of work on the amygdala.