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The Long-Term Benefits of Interventions to Improve T2D Outcomes

改善 T2D 结局的干预措施的长期益处

基本信息

批准号：
9321379
负责人：
DANA P GOLDMAN
金额：
$ 65.95万
依托单位：
UNIVERSITY OF SOUTHERN CALIFORNIA
依托单位国家：
美国
项目类别：
财政年份：
2016
资助国家：
美国
起止时间：
2016-07-22 至 2020-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9321379
关键词：
Accounting Adherence Admission activity Affect Amputation Blindness Body Weight decreased Cardiovascular system Clinical Clinical Trials Control Groups Data Data Linkages Dementia Diabetes Mellitus Direct Costs Disability Insurance Disease Disease Management Disease remission Economics Education Employment Enrollment Epidemiologist Etiology Goals Guidelines Health Health Care Costs Health Services Accessibility Health Status Healthcare Systems Heart Diseases Hospitals Hypertension Income Intervention Investments Kidney Failure Knowledge Lead Life Link Measures Medicare Medicare claim Methodology Modeling Morbidity - disease rate Non-Insulin-Dependent Diabetes Mellitus Outcome Participant Patients Physicians Population Public Assistance Public Health Quality of life Randomized Records Regimen Research Retirement Running Sleep Apnea Syndromes Societies Socioeconomic Status Source Stroke United States Social Security Administration Weight Work cardiovascular risk factor data modeling design diabetes control diabetes management diet and exercise disability economic impact economic implication economic outcome experience follow-up functional status health care service utilization health economics health related quality of life improved intervention effect lifestyle intervention mortality multidisciplinary social successful intervention weight loss intervention

项目摘要

Project Summary/ Abstract Diabetes is a mounting public health concern, with millions of new cases each year. Poor control of diabetes is associated with serious health complications, including heart disease, blindness, and amputation. Control of diabetes can be achieved through adherence to diet, exercise, and treatment guidelines, but compliance with prescribed regimens can be complicated and difficult. The Look AHEAD study randomized an intensive lifestyle intervention focused on weight reduction among over 5,000 patients with type 2 diabetes in 2001. Participants in the intervention lost weight and improved their diabetes control over the 11 years of the intervention relative to the control group. Weight reductions and improvements in diabetes outcomes may lead to broader benefits for patients in terms of functional status, ability to work, and fewer health complications. We propose research linking Look AHEAD participants with data from Medicare and the Social Security Administration to determine the effect of the intervention on long-term health care utilization (e.g. hospital admissions), employment, earnings, retirement, and severe disability (as measured by enrollment in disability insurance). In addition, we will simulate the long-term fiscal impacts of a broader, national expansion of the intensive lifestyle intervention. Finally, we will compare health and disability measures collected by the Look AHEAD study to overlapping measures in Medicare and the Social Security Administration data, to evaluate the use of administrative data as a source of health information in clinical trials. The results of this study will provide important evidence on the broader benefits of successful lifestyle interventions for diabetes. In addition, the results will indicate the impact of improved diabetes control on functional status and economic outcomes.

项目摘要/摘要