课题基金 / 基金详情

Understanding the context-dependent roles of mutations in lymphoma.

Understanding the context-dependent roles of mutations in lymphoma.
了解突变在淋巴瘤中的背景依赖性作用。
批准号：
9336685
负责人：
Sandeep Dave
金额：
$28.62万
依托单位：
DUKE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
项目状态：
已结题
起止时间：
2009-02-18 至 2019-08-31
来源：
https://reporter.nih.gov/project-details/9336685
关键词：
AccountingB-LymphocytesBiological ProcessBiologyCRISPR/Cas technologyClinicalComputing MethodologiesDNA Sequence AlterationDataData QualityDiseaseEmployee StrikesEventExclusionGene ExpressionGene Expression ProfileGene Expression ProfilingGene MutationGenerationsGenesGeneticGenetic HeterogeneityGoalsHeterogeneityHigh-Throughput Nucleotide SequencingHumanIn VitroIndividualInvestmentsKnockout MiceKnowledgeLinkLymphomaMalignant NeoplasmsMethodsModelingMolecularMolecular ProfilingMutateMutationOncogenicOutcomePathway interactionsPatient-Focused OutcomesPatientsPatternPhenotypeRecurrenceResearchRoleStructure of germinal center of lymph nodeSubgroupSystemTherapeuticTumor BiologyWorkbaseclinical phenotypeexome sequencinggenetic makeupimprovedin vivolarge cell Diffuse non-Hodgkin&aposs lymphomanext generation sequencingnovelnovel strategiesnovel therapeuticspublic health relevancescreeningtargeted sequencingtherapeutic targettranscriptometranscriptome sequencingtumor

项目摘要

项目成果

Sandeep Dave的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
DESCRIPTION (provided by applicant): Recent work from our group and others has provided a wealth of information regarding the genetic makeup of lymphomas and other tumors. However, it is unclear how these genetic mutations actually cause the disease and the degree to which they are associated with known biological processes and outcome. In this proposal, we seek to study how different genetic mutations are associated with known lymphoma phenotypes and the context-dependent roles of genetic mutations.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Genetic Origins of Adverse Outcomes in African Americans with Lymphoma
  • 批准号：
    10587289
  • 项目类别：
  • 资助金额：
    $48.57万
  • 财政年份：
    2023
  • 负责人：
    Sandeep Dave
  • 依托单位：
    DUKE UNIVERSITY
Clinical and Genetic Origins of Monomorphic Epitheliotropic Intestinal T Cell Lymphoma
  • 批准号：
    10566317
  • 项目类别：
  • 资助金额：
    $41.66万
  • 财政年份：
    2023
  • 负责人：
    Sandeep Dave
  • 依托单位：
    DUKE UNIVERSITY
Targeting histone methylation in PTCL
  • 批准号：
    10477033
  • 项目类别：
  • 资助金额：
    $29.22万
  • 财政年份：
    2019
  • 负责人：
    Sandeep Dave
  • 依托单位：
    DANA-FARBER CANCER INST
Targeting histone methylation in PTCL
  • 批准号：
    9791868
  • 项目类别：
  • 资助金额：
    $31.76万
  • 财政年份：
    2019
  • 负责人：
    Sandeep Dave
  • 依托单位：
    DANA-FARBER CANCER INST
海外基金