Hopkins Center to Promote resilience in persons and families living with multiple chronic conditions (the PROMOTE Center)

霍普金斯促进患有多种慢性病的个人和家庭的复原力中心（PROMOTE 中心）

• 批准号: 10214696
• 负责人: HAE-RA HAN
• 金额: $ 45.9万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-08-22 至 2023-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10214696
• 关键词: Address; Adoption; Adult; Affective; Age; Area; Attention; Behavior Therapy; Biological Markers; Businesses; Caregivers; Caring; Cells; Cessation of life; Chronic; Communication; Communities; Community Health Systems; Consultations; Development; Discipline of Nursing; Elderly; Environment; Evaluation; Family; Family Caregiver; Fatigue; Fostering; Generations; Genomics; Goals; Habits; Health; Healthcare; Home; Individual; Infrastructure; Insurance; Interdisciplinary Study; Intervention; Intervention Studies; Knowledge; Lead; Life; Logic; Measures; Mentorship; Methodology; Methods; Modeling; Nurses; Pain; Participant; Persons; Phase; Physiological; Physiological Processes; Pilot Projects; Policies; Population; Positioning Attribute; Process; Provider; Quality of life; Research; Research Personnel; Resource Development; Resources; Risk; Science; Scientist; Societies; Testing; Translations; United States; Work; base; biobehavior; career; contextual factors; cytokine; design; disability; evidence base; experience; frailty; health care service utilization; improved; informal caregiver; innovation; member; multidisciplinary; multiple chronic conditions; preference; resilience; skills; social health determinants; theories; therapy development; uptake

Developing feasible, effective and scalable interventions to improve health among people with multiple chronic conditions is urgent. However, research gaps hinder intervention development. Most interventions do not consider co-occurring functional limitations, family caregivers' perspectives or contextual factors that define social determinants of health. Moreover, interventions commonly focus on deficits rather than strengths. These limitations are compounded by lack of communication among practitioners and people experiencing multiple chronic conditions about their goals, values, and preferences. The proposed Hopkins Center to Promote resilience in persons and families living with multiple chronic conditions (the PROMOTE Center) is poised to address these gaps. The PROMOTE Center will leverage a unique combination of interdisciplinary expertise in 1) behavioral intervention research 2) research and statistical methodology and 3) physiological processes including cytokines found in sweat. Early, mid-career and senior researchers, persons and families experiencing multiple chronic conditions, and key translational stakeholders will work together to advance the science of improving health among those with multiple chronic conditions using our innovative ecological resilience framework. This framework conceptualizes resilience as a life-long process impacted by cumulative interaction of multiple inter-related factors, such as society, community, and family, individual, physiologic and genomic factors. The PROMOTE Center will advance science to improve health and care of adults with multiple chronic conditions by providing expertise, mentorship and resources for the development, implementation and evaluation of theory-driven interdisciplinary research through three Aims. Aim 1: Establish a community-informed, sustainable infrastructure with dedicated resources to advance interdisciplinary nursing science that improves the health of vulnerable adults with multiple chronic conditions and their family caregivers: Aim 2: Foster a new generation of nursing scholars with skills to lead interdisciplinary research that improves the resilience of adults with multiple chronic conditions. Aim 3: Leverage unique environmental strengths to enhance dissemination and translation of evidence-based multiple chronic condition interventions through established partnerships with key stakeholders. Key innovations of the PROMOTE Center include: 1) Use of Society to Cells Resilience Framework that supports focus on health phases in which people are most likely to be open to new information and habits; 2) Integration of exploratory aims in pilot studies measuring bio- markers of resilience with non-invasive sweat measures developed at NINR; and 3) User-centered strengths- based co-design approaches at each phase of pilot development leading to enhanced participant uptake and higher likelihood of sustainability and translation to other settings.

制定可行、有效和可扩展的干预措施，以改善多种慢性病患者的健康状况 条件紧迫。然而，研究差距阻碍了干预措施的发展。大多数干预措施并不 考虑共同发生的功能限制，家庭照顾者的观点或背景因素， 健康的社会决定因素。此外，干预措施通常侧重于缺陷而不是优势。这些 由于从业人员和经历多种疾病的人之间缺乏沟通， 慢性病患者的目标、价值观和偏好。拟议中的霍普金斯促进中心 生活在多种慢性疾病中的个人和家庭的恢复力（PROMOTE中心）已经准备好 来弥补这些差距。PROMOTE中心将利用跨学科专业知识的独特组合 在1）行为干预研究2）研究和统计方法和3）生理过程 包括汗液中的细胞因子早期、中期和高级研究人员，经历过 多种慢性疾病，关键的转化利益相关者将共同努力，推动科学的发展， 利用我们创新的生态恢复力改善患有多种慢性疾病的人的健康状况 框架.该框架将复原力概念化为受累积相互作用影响的终身过程 社会、社区、家庭、个体、生理、基因组等多种因素相互作用的结果 因素PROMOTE中心将推进科学，以改善患有多种慢性疾病的成年人的健康和护理。 通过为发展、实施和评价提供专门知识、指导和资源， 通过三个目标的理论驱动的跨学科研究。目标1：建立一个社区知情、 可持续的基础设施与专用资源，以推进跨学科的护理科学，提高 患有多种慢性病的脆弱成年人及其家庭照顾者的健康：目标2： 一代护理学者，具有领导跨学科研究的技能，可提高成年人的复原力 患有多种慢性病目标3：利用独特的环境优势加强传播和 通过与关键的合作伙伴建立伙伴关系， 持份者PROMOTE中心的主要创新包括： 1)使用社会对细胞复原力框架，支持关注人们最需要的健康阶段 可能对新的信息和习惯持开放态度; 2）将探索性目标纳入测量生物- 在NINR开发的非侵入性汗液测量的弹性标记;以及3）以用户为中心的优势- 在试点开发的每个阶段采用基于共同设计的方法，从而提高参与者的接受程度， 更高的可持续性和转换到其他环境的可能性。