CAP - Consortium to Alleviate PTSD - STVHCS Project 7

项目#7-创伤后认知行为疗法的随机临床试验 这项研究的目的是为人性化的行为建立第一个证据基础 PTHA的管理协议。主要的研究目标是评估一种 对患有以下疾病的服役人员进行基于临床的非药物认知行为干预(CBT) PTHA经历过与爆炸相关的创伤事件，导致创伤后应激障碍和mTBI症状。 目的：进行3组随机临床试验，观察(1)临床认知功能障碍的疗效。 行为疗法(CCBT)；(2)最小治疗师接触认知行为疗法(MCCBT)； 和(3)6周治疗师监测(TM)控制条件，用于治疗慢性创伤后 现役军人和退伍军人令人头疼。目的2：评价人与人之间的关系 脑震荡后认知症状和创伤后应激症状的初步治疗 结果。目标3(探索性)：检查生物标记物和成像数据对 阐明影响PTHA慢性化和治疗反应的因素。

Project #7 - Randomized Clinical Trial of Cognitive-Behavior Therapy for Posttraumatic The purpose of this study is to establish the first basis of evidence for a manualized behavioral management protocol for PTHA. The primary study objective is to evaluate the effectiveness of a non-medication, clinic-based cognitive-behavioral intervention (CBT) for service members with PTHA who have experienced a blast-related traumatic event resulting in PTSD and mTBI symptoms. Aim 1: To conduct a 3-group randomized clinical trial of the efficacy of (1) clinic-based cognitive- behavioral therapy (CCBT); (2) minimal therapist-contact cognitive-behavioral therapy (MCCBT); and (3) a 6-week therapist monitored (TM) control condition for treatment of chronic posttraumatic headache within active-duty military personal and veterans. Aim 2: To evaluate the relationship of post-concussive cognitive symptoms and posttraumatic stress symptoms to primary treatment outcomes. Aim 3 (Exploratory): To examine the contribution of biomarker and imaging data to illuminate factors that contribute to PTHA chronicity and treatment response.