Pilot Project Core

试点项目核心摘要 本土酒精研究和教育中心(NCARE)的目标是培育创新研究 关于美国印第安人和阿拉斯加原住民(AI/ANS)由于酒精使用障碍(AUD)而造成的健康不平等， 包括他们的预防、诊断、治疗和一生中的后果。一项关键战略 实现这一目标是为了资助试点项目，这些项目将开发新的方法来改善人工智能/人工智能人口 健康。试点项目提供了一种方式来播种新兴研究领域，探索新的方法，并追求 新的区域和国家合作可能演变为独立资助的研究或示范 项目。现有的基于大学的试点资金方案提供的金额有限(例如，5,000-10,000美元)， 往往不足以进行基于社区的研究，通常仅限于家中的调查人员 机构。NCARE的试点项目核心旨在确定并分配大量资金用于支持 试点项目，严格测试实践、治疗、教育努力和政策，以实现可持续、 由于AUDS，AI/AN健康差距普遍缩小。我们将招募范围广泛的调查人员 来自NCARE和外部机构，他们可以在试点项目的支持下开始或加强他们的研究 核心。鉴于对由美国国家科学院资助的科学劳动力老龄化的严重关切 健康，以及同样令人担忧的少数族裔首席调查人员的缺乏，我们将鼓励来自 初级教员和人工智能/人工智能调查人员。试点项目核心将提供无数的研究可能性，包括 但不限于AUDS的病因学、生物学、遗传学、诊断、治疗和预防的研究 他们的生物医学、心理社会和经济后果。我们的具体目标是：1)创建试点项目 核心资金用于资助对AUDS和相关健康不平等具有重大影响的创新试点项目 AI/AN社区；2)将科学审查过程作为初级调查人员的学习机会 希望回顾经验的NCARE成员；以及3)开发集中的研究服务，以支持 领导NCARE试点项目的调查人员，包括对酒精有浓厚兴趣的初级调查人员 研究。我们还将利用我们在其他小额赠款计划方面的成功经验，提供资金、 向那些建议符合我们严格标准的研究人员提供后勤、科学资源。通过创建一个 集中研究支持服务并为NCARE试点项目分配大量财政资源，这 方法将培育一个创新和严谨研究的生态系统。试点项目核心的活动 将支持全国范围内的研究人员，从而为发展新的科学方法做出贡献， 国家范围内与创新的、以目标为导向的联合技术开发研究相关的技术和方法。

PILOT PROJECT CORE ABSTRACT The goal of the Native Center for Alcohol Research and Education (NCARE) is to nurture innovative research on health inequities among American Indians and Alaska Natives (AI/ANs) due to alcohol use disorders (AUDs), including their prevention, diagnosis, treatment, and consequences across the lifespan. One critical strategy for achieving this goal is to fund pilot projects that will develop novel approaches to improving AI/AN population health. Pilot projects provide a way to seed emerging research areas, explore new methodologies, and pursue new regional and national collaborations that could evolve into independently funded research or demonstration projects. Existing university-based options for pilot funding provide limited sums (e.g., $5,000-$10,000) that are often inadequate to conduct community-based research and are typically restricted to investigators at the home institution. The Pilot Project Core of NCARE is designed to identify and allocate substantial funding to support pilot projects that rigorously test practices, treatments, educational efforts, and policies that can effect sustained, widespread reductions in AI/AN health disparities due to AUDs. We will recruit a broad range of investigators from NCARE and outside institutions who can begin or augment their research with support from the Pilot Project Core. Given serious concerns about the aging of the scientific workforce funded by the National Institutes of Health, and the equally worrisome dearth of minority Principal Investigators, we will encourage applications from junior faculty and AI/AN investigators. The Pilot Project Core will offer myriad possibilities for research, including but not limited to studies of the etiology, biology, genetics, diagnosis, treatment, and prevention of AUDs and their biomedical, psychosocial, and economic consequences. Our Specific Aims are to: 1) Create a Pilot Project Core to fund innovative Pilot Projects with meaningful implications for AUDs and related health inequities in AI/AN communities; 2) Use the scientific review process as a learning opportunity for junior investigators and NCARE members who desire reviewing experience; and 3) Develop centralized research services that support the investigators who lead NCARE Pilot Projects, including junior investigators with a strong interest in alcohol research. We will also leverage our successful experience with other small grant programs to offer financial, logistical, and scientific resources to researchers whose proposals meet our rigorous criteria. By creating a centralized research support service and allocating substantial financial resources for NCARE Pilot Projects, this approach will foster an ecosystem of innovative and rigorous research. The activities of the Pilot Project Core will support investigators nationwide, thereby contributing to the development of new scientific methods, technologies, and approaches pertinent to innovative, goal-directed AUD research on a national scale.