Administrative Core

行政核心

• 批准号: 9282694
• 负责人: YOSHIHIRO KAWAOKA
• 金额: $ 51.53万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至 2020-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9282694
• 关键词: Attention; Biological; Budgets; Cells; Collaborations; Communicable Diseases; Communication; Communication Methods; Communities; Computer Analysis; Computer Simulation; Computer software; Congresses; Data; Data Analyses; Databases; Deposition; Development; Diamond; Disease; Ebola virus; Educational workshop; Electronic Mail; Elements; Ensure; Event; Fostering; Funding; Funding Opportunities; Goals; Grant; Hand; Human; Human Resources; Immune response; Infection; Instruction; Journals; Knockout Mice; Laboratories; Lead; Leadership; Learning; Link; Management Information Systems; Modeling; Monitor; National Institute of Allergy and Infectious Disease; Outcome; Output; Participant; Pathogenicity; Peer Review; Persons; Pilot Projects; Principal Investigator; Proteomics; Publications; Research; Research Activity; Research Infrastructure; Research Personnel; Research Project Grants; Resource Sharing; Resources; Scheme; Scholarship; Scientist; Services; Systems Biology; Technology; Teleconferences; Therapeutic; TimeLine; Training Programs; Universities; Virus; Virus Diseases; Water; West Nile virus; Wisconsin; cost; data management; data mining; data portal; data resource; data sharing; design; improved; in vivo; influenzavirus; innovation; meetings; member; metabolomics; new technology; parent project; programs; repository; response; skills; symposium; time use; validation studies; web portal

The Administrative Core for the project entitled "Modeling Host Responses to Understand Severe Human Virus Infections" will provide support to the Research projects (RPI: Influenza and Ebola virus research; RP2: West Nile virus research project) and the other project cores (Core A: Proteomics, Metabolomics and Lipidomics Core; Core B: Computational Modeling Core; Core C: Data Dissemination and Resource Sharing Core) and coordinate project activities. The overall objective of the project is to characterize host cell responses that determine the outcome of potentially lethal viral infections. As Principal Investigator and Leader of the Administrative Core, Dr. Yoshihiro Kawaoka will be responsible for the overall project and for meeting the objectives outlined. The Administrative Core will (1) assemble the staff needed to meet the objectives outlined in the project proposal, ensuring the expertise and commitment is commensurate with project goals; (2) identify milestones and establish timelines which will be reviewed frequently to keep the project on target; (3) oversee budget resources to. optimize outputs and ensure spending is appropriate; (4) foster good communications among members of the projects and cores via regular webcasts, in-person meetings and frequent email contact, and provide regular interaction with the NIAID Project Scientist and the Steering Committee; (5) support the data management and resource sharing objectives, curate the Laboratory Information Management System (LIMS), ensure data sharing within the project is optimized, and that data and resources are shared promptly via a public web portal for data and public repositories for data, analyses, software, models and biological resources; (6) develop a Training Program to help other infectious disease researchers learn about OMICs approaches and (7) establish a Pilot Research Program to fund short-term innovative projects relevant to the project.

题为“模拟宿主反应以了解严重人类免疫缺陷综合征”的项目的行政核心 病毒感染”将为研究项目提供支持（RPI：流感和埃博拉病毒研究; RP 2：西尼罗河病毒研究项目）和其他项目核心（核心A：蛋白质组学、代谢组学和 脂质组学核心;核心B：计算建模核心;核心C：数据传播和资源共享 核心）和协调项目活动。该项目的总体目标是表征宿主细胞 决定潜在致命病毒感染结果的反应。作为主要研究者， 行政核心的领导人，川冈义弘博士将负责整个项目， 达到所列目标。行政核心将（1）召集所需的工作人员， 项目建议书中概述的目标，确保专业知识和承诺与 项目目标;（2）确定里程碑，并建立时间表，将经常审查，以保持 项目目标;（3）监督预算资源。优化产出，确保支出适当;（4） 通过定期网络直播，促进项目成员和核心成员之间的良好沟通， 会议和频繁的电子邮件联系，并提供与NIAID项目科学家和 指导委员会;（5）支持数据管理和资源共享目标， 实验室信息管理系统（LIMS），确保项目内的数据共享得到优化，以及 通过公共数据门户网站和公共数据储存库迅速分享数据和资源， 分析，软件，模型和生物资源;（6）制定培训计划，以帮助其他传染病 疾病研究人员了解OMIC的方法和（7）建立一个试点研究计划，以资助 与项目相关的短期创新项目。