UT Southwestern Center for Translational Medicine

德州大学西南转化医学中心

• 批准号: 10349047
• 负责人: Keith Edward Argenbright
• 金额: $ 130.63万
• 依托单位: UT SOUTHWESTERN MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-05-26 至 2026-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10349047
• 关键词: Academy; Acceleration; Address; Applications Grants; Award; Awareness; Basic Science; Career Choice; Clinical Research; Collaborations; Communities; Community Health; Competence; Cost Sharing; Custom; Development; Discipline; Educational Curriculum; Elements; Ensure; Evaluation; Exposure to; Faculty; Fostering; Frequencies; Funding; Future; Gender; Generations; Goals; Grant; Health; Incubators; Individual; Informatics; Institution; K-Series Research Career Programs; Manuscripts; Medicine; Mentors; Mentorship; Modeling; Modernization; NCI Scholars Program; Physicians; Program Development; Program Evaluation; Research; Research Personnel; Research Project Grants; Research Training; Resources; Role; Science; Scientist; Secure; Series; Structure; Team Process; Technology; Texas; Thinking; Time; TimeLine; Training; Training Programs; Training and Infrastructure; Translational Research; Translations; Vocational Guidance; Woman; base; career; career development; community engagement; design; empowered; ethnic minority population; externship; improved; innovation; interdisciplinary collaboration; peer; peer coaching; pre-clinical research; programs; racial and ethnic; recruit; success; theories; tool; translational medicine; translational pipeline

The UT Southwestern Center for Translational Medicine's (CTM) KL2 Scholars Program already has a proven track record for growing a new generation of Scholars who have become leaders in clinical and translational research (CTR). Our KL2 program, with an ethos of continuous improvement based on metrics and changing needs, has been a model of unique and centralized CTR training in our Hub. Our training curriculum has been streamlined and modernized, and the diversity of our Scholars across all important domains has greatly increased. In the new grant cycle, we will elevate our KL2 program to the next level through innovative programming and cost sharing of CTSA, institutional and hub resources. We will appoint three new KL2 Scholars per year for a two-year term (ongoing total of six/year). KL2 Scholars will engage in mentored research training, take formal coursework and short nanocourses on emerging CTR topics, and submit manuscripts and grant proposals to secure individual career development and/or research grants (K2K and K2R conversion, respectively) in a timely manner, to minimize the career-disrupting “K-cliff.” Careful program evaluation will guide us to restructure elements further to increase the diversity of those we train and broaden the disciplines and institutions from which the Scholars are recruited. The new KL2 plan proposed here is significant and innovative. We will strategically leverage CTSA core and institutional resources to broaden the KL2 program's impact and provide CTR training to an expanding pool of biomedical workforce. The four Aims are integrated through our unique culturally-aware Tiered Mentorship Model, which includes mentorship by primary and secondary research mentors, program directors, near-peer mentors, and Scholar self-mentoring. We propose: Aim 1. Ensure personalized research career development, with customization by a faculty-level Curriculum Navigator and a longitudinal training roadmap; Aim 2. Catalyze collaboration and innovation by launching team science, community engagement, innovator studios and women in technology programs; Aim 3. Promote K2R conversion to independent investigators by strengthening longitudinal K2R progression along the K2R roadmap, creating an Interdiscipinary Sandwich Junior Mentor-in- Training Program and a CTR-Scientific Management program to address unique needs of junior CTR PIs; Aim 4. Expand and strengthen the diverse CTR investigator pipeline by providing CTR training to existing underrepresented trainee career development programs. Impact: Institutional resources will be leveraged to expand the KL2's footprint and enlarge the CTR Scholar community. Rigorous evaluation metrics will be used to enable us to improve our program iteratively. Our forward-thinking and integrated training paradigm will greatly expand the number of Scholars armed with the tools for success and empowered to anticipate and adapt effectively to become CTR leaders of the future.

德克萨斯大学西南转化医学中心(CTM)的KL2奖学金计划已经有一个经过验证的 培养成为临床和翻译领域领导者的新一代学者的记录 研究(CTR)。我们的KL2计划，本着基于指标和不断变化的持续改进的精神 根据我们的需求，CTR培训已成为我们中心独特的集中式CTR培训模式。我们的培训课程一直是 精简和现代化，我们学者在所有重要领域的多样性大大 增加了。在新的赠款周期中，我们将通过创新的方式将我们的KL2计划提升到下一个水平 CTSA、机构和中心资源的规划和费用分担。我们将委任三名新的九龙二期 每年一次，为期两年(目前共六人/年)。KL2学者将参与指导 研究培训，参加关于新出现的CTR主题的正式课程和短期纳米课程，并提交 手稿和赠款建议，以确保个人职业发展和/或研究补助金(K2K和 分别为K2R转换)，及时将打乱职业生涯的“K-克里夫”降至最低。精心制作的节目 评估将指导我们进一步重组要素，以增加我们培训和扩大的要素的多样性 奖学金获得者的学科和机构。这里提出的新的九龙线二期计划是 具有重大意义和创新性。我们将战略性地利用CTSA的核心和机构资源，以扩大 KL2计划的影响，并为不断扩大的生物医学劳动力池提供CTR培训。四个 AIMS通过我们独特的文化意识分层导师模式进行整合，该模式包括 由主要和次要研究导师、项目主任、近同行导师和学者提供的指导 自我辅导。我们建议：目标1.确保个性化的研究职业发展，并进行定制 通过教职员工级课程导航器和纵向培训路线图；目标2.促进协作 通过推出团队科学、社区参与、创新者工作室和妇女在 技术方案；目标3.通过加强以下方面促进K2R向独立调查人员转变 沿着K2R路线图纵向推进K2R，创建跨学科三明治初级导师- 培训计划和CTR-科学管理计划，以满足初级CTR PI的独特需求；目标 4.通过向现有CTR调查员提供CTR培训，扩大和加强多样化的CTR调查员渠道 代表不足的实习生职业发展计划。影响：机构资源将被利用来 扩大九龙仓S足迹，扩大华侨华人学者社区。将使用严格的评估指标 使我们能够迭代地改进我们的计划。我们的前瞻性思维和综合培训模式将 大大增加拥有成功工具的学者的数量，并使其能够预见和 有效地适应，成为未来的CTR领导者。